PRESIDENTIAL ADDRESS:

TCR Signal Transduction: Opening the Black Box

Arthur Weiss
J Immunol 2009 183: 4821-4827; doi:10.4049/jimmunol.0990083 [Full Text] [PDF]  

IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2009 183: 4829-4830; doi:10.4049/jimmunol.0990084 [Full Text] [PDF] ImmunoCast  

LETTERS TO THE EDITOR:

Comment on "Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients"

Olga Krysko, Thibaut Van Zele, Sofie Claeys, and Claus Bachert
J Immunol 2009 183: 4831-4832; doi:10.4049/jimmunol.0990081 [Full Text] [PDF]  

Response to Comment on "Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients"

Franciso García-Río, Carlos del Fresno, Pablo Fuentes-Prior, and Eduardo López-Collazo
J Immunol 2009 183: 4831-4832; doi:10.4049/jimmunol.0990082 [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Importance of IL-6 and Cooperation between Innate and Adaptive Immune Receptors in Cellular Vaccination with B Lymphocytes

Tony J. Vanden Bush, Claire M. Buchta, Jennifer Claudio, and Gail A. Bishop
J Immunol 2009 183: 4833-4837; doi:10.4049/jimmunol.0900968 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Extracellular Signal-Related Kinase Is Not Required for Negative Selection of Developing T Cells

Maureen A. McGargill, Irene L. Ch'en, Carol D. Katayama, Gilles Pagès, Jacques Pouysségur, and Stephen M. Hedrick
J Immunol 2009 183: 4838-4842; doi:10.4049/jimmunol.0902208 [Abstract] [Full Text] [PDF]  

Cutting Edge: Responder T Cells Regulate Human DR⁺ Effector Regulatory T Cell Activity via Granzyme B

Charles W. Ashley and Clare Baecher-Allan
J Immunol 2009 183: 4843-4847; doi:10.4049/jimmunol.0900845 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: Tumor-Specific CD8⁺ T Cells Infiltrating Prostatic Tumors Are Induced to Become Suppressor Cells

Kimberly A. Shafer-Weaver, Michael J. Anderson, Katherine Stagliano, Anatoli Malyguine, Norman M. Greenberg, and Arthur A. Hurwitz
J Immunol 2009 183: 4848-4852; doi:10.4049/jimmunol.0900848 [Abstract] [Full Text] [PDF] Data Supplement  

Cutting Edge: OX40 Agonists Can Drive Regulatory T Cell Expansion if the Cytokine Milieu Is Right

Carl E. Ruby, Melissa A. Yates, Daniel Hirschhorn-Cymerman, Peter Chlebeck, Jedd D. Wolchok, Alan N. Houghton, Halina Offner, and Andrew D. Weinberg
J Immunol 2009 183: 4853-4857. Published online September 28, 2009; doi:10.4049/jimmunol.0901112 [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Functionally Mature CD4 and CD8 TCRβ Cells Are Generated in OP9-DL1 Cultures from Human CD34⁺ Hematopoietic Cells

Stefanie Van Coppernolle, Greet Verstichel, Frank Timmermans, Imke Velghe, David Vermijlen, Magda De Smedt, Georges Leclercq, Jean Plum, Tom Taghon, Bart Vandekerckhove, and Tessa Kerre
J Immunol 2009 183: 4859-4870; doi:10.4049/jimmunol.0900714 [Abstract] [Full Text] [PDF] Data Supplement  

Evidence for Local Expansion of IgA Plasma Cell Precursors in Human Ileum

Saravanan Yuvaraj, Gerard Dijkstra, Johannes G. M. Burgerhof, Peter M. Dammers, Maaike Stoel, Annie Visser, Frans G. M. Kroese, and Nicolaas A. Bos
J Immunol 2009 183: 4871-4878. Published online September 28, 2009; doi:10.4049/jimmunol.0901315 [Abstract] [Full Text] [PDF] Data Supplement  

Essential Roles for Dok2 and RasGAP in CD200 Receptor-Mediated Regulation of Human Myeloid Cells

Robin Mihrshahi, A. Neil Barclay, and Marion H. Brown
J Immunol 2009 183: 4879-4886. Published online September 28, 2009; doi:10.4049/jimmunol.0901531 [Abstract] [Full Text] [PDF]  

PU.1 Regulates TCR Expression by Modulating GATA-3 Activity

Hua-Chen Chang, Ling Han, Rukhsana Jabeen, Sebastian Carotta, Stephen L. Nutt, and Mark H. Kaplan
J Immunol 2009 183: 4887-4894; doi:10.4049/jimmunol.0900363 [Abstract] [Full Text] [PDF]  

Dominant Role of Antigen Dose in CD4⁺Foxp3⁺ Regulatory T Cell Induction and Expansion

Michael S. Turner, Lawrence P. Kane, and Penelope A. Morel
J Immunol 2009 183: 4895-4903; doi:10.4049/jimmunol.0901459 [Abstract] [Full Text] [PDF] Data Supplement  

In Vivo Expansion of Activated Naive CD8⁺ T Cells and NK Cells Driven by Complexes of IL-2 and Anti-IL-2 Monoclonal Antibody As Novel Approach of Cancer Immunotherapy

Jakub Tomala, Helena Chmelova, Tomas Mrkvan, Blanka Rihova, and Marek Kovar
J Immunol 2009 183: 4904-4912; doi:10.4049/jimmunol.0900284 [Abstract] [Full Text] [PDF] Data Supplement  

Autoimmunity during Thymectomy-Induced Lymphopenia: Role of Thymus Ablation and Initial Effector T Cell Activation Timing in Nonobese Diabetic Mice

Marie-Claude Gagnerault, Olivia Lanvin, Virginie Pasquier, Corinne Garcia, Diane Damotte, Bruno Lucas, and Françoise Lepault
J Immunol 2009 183: 4913-4920; doi:10.4049/jimmunol.0901954 [Abstract] [Full Text] [PDF]  

Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells

Mattias Carlsten, Håkan Norell, Yenan T. Bryceson, Isabel Poschke, Kjell Schedvins, Hans-Gustaf Ljunggren, Rolf Kiessling, and Karl-Johan Malmberg
J Immunol 2009 183: 4921-4930; doi:10.4049/jimmunol.0901226 [Abstract] [Full Text] [PDF] Data Supplement  

Recombination Signal Sequence-Associated Restriction on TCR Gene Rearrangement Affects the Development of Tissue-Specific T Cells

Uzodinma N. Uche, Christopher R. Huber, David H. Raulet, and Na Xiong
J Immunol 2009 183: 4931-4939; doi:10.4049/jimmunol.0901859 [Abstract] [Full Text] [PDF] Data Supplement  

SH2 Domain-Containing Phosphatase-2 Protein-Tyrosine Phosphatase Promotes FcRI-Induced Activation of Fyn and Erk Pathways Leading to TNF Release from Bone Marrow-Derived Mast Cells

Victor A. McPherson, Namit Sharma, Stephanie Everingham, Julie Smith, Helen H. Zhu, Gen-Sheng Feng, and Andrew W. B. Craig
J Immunol 2009 183: 4940-4947. Published online September 28, 2009; doi:10.4049/jimmunol.0900702 [Abstract] [Full Text] [PDF]  

Dendritic Cells Support the In Vivo Development and Maintenance of NK Cells via IL-15 Trans-Presentation

Eliseo F. Castillo, Spencer W. Stonier, Loredana Frasca, and Kimberly S. Schluns
J Immunol 2009 183: 4948-4956. Published online September 28, 2009; doi:10.4049/jimmunol.0900719 [Abstract] [Full Text] [PDF]  

Differential Effect of IL-27 on Developing versus Committed Th17 Cells

Mohamed El-behi, Bogoljub Ciric, Shuo Yu, Guang-Xian Zhang, Denise C. Fitzgerald, and Abdolmohamad Rostami
J Immunol 2009 183: 4957-4967. Published online September 28, 2009; doi:10.4049/jimmunol.0900735 [Abstract] [Full Text] [PDF] Data Supplement  

CD94 Defines Phenotypically and Functionally Distinct Mouse NK Cell Subsets

Jianhua Yu, Min Wei, Hsiaoyin Mao, Jianying Zhang, Tiffany Hughes, Takeki Mitsui, Il-kyoo Park, Christine Hwang, Shujun Liu, Guido Marcucci, Rossana Trotta, Don M. Benson, Jr., and Michael A. Caligiuri
J Immunol 2009 183: 4968-4974; doi:10.4049/jimmunol.0900907 [Abstract] [Full Text] [PDF] Data Supplement  

The E3 Ubiquitin Ligase Cbl-b Regulates Expansion but Not Functional Activity of Self-Reactive CD4 T Cells

Marie-Clare St. Rose, Harry Z. Qui, Suman Bandyopadhyay, Marianne A. Mihalyo, Adam T. Hagymasi, Robert B. Clark, and Adam J. Adler
J Immunol 2009 183: 4975-4983; doi:10.4049/jimmunol.0901243 [Abstract] [Full Text] [PDF]  

Costimulatory Pathways in Multiple Sclerosis: Distinctive Expression of PD-1 and PD-L1 in Patients with Different Patterns of Disease

Daria Trabattoni, Marina Saresella, Michela Pacei, Ivana Marventano, Laura Mendozzi, Marco Rovaris, Domenico Caputo, Manuela Borelli, and Mario Clerici
J Immunol 2009 183: 4984-4993. Published online September 30, 2009; doi:10.4049/jimmunol.0901038 [Abstract] [Full Text] [PDF]  

TCR Down-Regulation Controls T Cell Homeostasis

Lasse Boding, Charlotte Menné Bonefeld, Bodil L. Nielsen, Jens Peter H. Lauritsen, Marina Rode von Essen, Ann Kathrine Hansen, Jeppe Madura Larsen, Morten Milek Nielsen, Niels Ødum, and Carsten Geisler
J Immunol 2009 183: 4994-5005; doi:10.4049/jimmunol.0901539 [Abstract] [Full Text] [PDF] Data Supplement  

CD8⁺ Cell Depletion of SHIV89.6P-Infected Macaques Induces CD4⁺ T Cell Proliferation that Contributes to Increased Viral Loads

Yvonne M. Mueller, Duc H. Do, Jean D. Boyer, Muhamuda Kader, Joseph J. Mattapallil, Mark G. Lewis, David B. Weiner, and Peter D. Katsikis
J Immunol 2009 183: 5006-5012. Published online September 28, 2009; doi:10.4049/jimmunol.0900141 [Abstract] [Full Text] [PDF]  

Acquisition of T Regulatory Function in Cathepsin L-Inhibited T Cells by Eye-Derived CTLA-2 during Inflammatory Conditions

Sunao Sugita, Shintaro Horie, Orie Nakamura, Kazuichi Maruyama, Hiroshi Takase, Yoshihiko Usui, Masaru Takeuchi, Kazumi Ishidoh, Masato Koike, Yasuo Uchiyama, Christoph Peters, Yoshimi Yamamoto, and Manabu Mochizuki
J Immunol 2009 183: 5013-5022; doi:10.4049/jimmunol.0901623 [Abstract] [Full Text] [PDF]  

Eosinophils Oxidize Damage-Associated Molecular Pattern Molecules Derived from Stressed Cells

Ramin Lotfi, Gloria Isabelle Herzog, Richard Anthony DeMarco, Donna Beer-Stolz, James Joseph Lee, Anna Rubartelli, Hubert Schrezenmeier, and Michael Thomas Lotze
J Immunol 2009 183: 5023-5031. Published online September 30, 2009; doi:10.4049/jimmunol.0900504 [Abstract] [Full Text] [PDF]  

CD11c^high Dendritic Cells Are Essential for Activation of CD4⁺ T Cells and Generation of Specific Antibodies following Mucosal Immunization

Linda Fahlén-Yrlid, Tobias Gustafsson, Jessica Westlund, Anna Holmberg, Anna Strömbeck, Margareta Blomquist, Gordon G. MacPherson, Jan Holmgren, and Ulf Yrlid
J Immunol 2009 183: 5032-5041. Published online September 28, 2009; doi:10.4049/jimmunol.0803992 [Abstract] [Full Text] [PDF]  

Lessons from Thymic Epithelial Heterogeneity: FoxN1 and Tissue-Restricted Gene Expression by Extrathymic, Endodermally Derived Epithelium

James Dooley, Matthew Erickson, and Andrew G. Farr
J Immunol 2009 183: 5042-5049. Published online September 28, 2009; doi:10.4049/jimmunol.0901371 [Abstract] [Full Text] [PDF]  

Elevated Levels of Select Gangliosides in T Cells from Renal Cell Carcinoma Patients Is Associated with T Cell Dysfunction

Soumika Biswas, Kaushik Biswas, Amy Richmond, Jennifer Ko, Sankar Ghosh, Matthew Simmons, Patricia Rayman, Brian Rini, Inderbir Gill, Charles S. Tannenbaum, and James H. Finke
J Immunol 2009 183: 5050-5058; doi:10.4049/jimmunol.0900259 [Abstract] [Full Text] [PDF]  

Long-Lived Colitogenic CD4⁺ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis

Yasuhiro Nemoto, Takanori Kanai, Kaori Kameyama, Tamako Shinohara, Naoya Sakamoto, Teruji Totsuka, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Tetsuo Sudo, Satoshi Matsumoto, and Mamoru Watanabe
J Immunol 2009 183: 5059-5068. Published online September 28, 2009; doi:10.4049/jimmunol.0803684 [Abstract] [Full Text] [PDF]  

Enhanced Dendritic Cell-Induced Immune Responses Mediated by the Novel C-Type Lectin Receptor mDCAR1

Stefan A. Kaden, Stefanie Kurig, Katrin Vasters, Kay Hofmann, Kurt S. Zaenker, Juergen Schmitz, and Gregor Winkels
J Immunol 2009 183: 5069-5078. Published online September 28, 2009; doi:10.4049/jimmunol.0900908 [Abstract] [Full Text] [PDF] Data Supplement  

The Survival of Memory CD4⁺ T Cells within the Gut Lamina Propria Requires OX40 and CD30 Signals

David R. Withers, Elin Jaensson, Fabrina Gaspal, Fiona M. McConnell, Bertus Eksteen, Graham Anderson, William W. Agace, and Peter J. L. Lane
J Immunol 2009 183: 5079-5084. Published online September 28, 2009; doi:10.4049/jimmunol.0901514 [Abstract] [Full Text] [PDF]  

Langerhans Cells Suppress Contact Hypersensitivity Responses Via Cognate CD4 Interaction and Langerhans Cell-Derived IL-10

Botond Z. Igyarto, Matthew C. Jenison, Jan C. Dudda, Axel Roers, Werner Müller, Pandelakis A. Koni, Daniel J. Campbell, Mark J. Shlomchik, and Daniel H. Kaplan
J Immunol 2009 183: 5085-5093; doi:10.4049/jimmunol.0901884 [Abstract] [Full Text] [PDF] Data Supplement  

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

David Préfontaine, Stéphane Lajoie-Kadoch, Susan Foley, Séverine Audusseau, Ron Olivenstein, Andrew J. Halayko, Catherine Lemière, James G. Martin, and Qutayba Hamid
J Immunol 2009 183: 5094-5103; doi:10.4049/jimmunol.0802387 [Abstract] [Full Text] [PDF]  

Phospholipase D Promotes Lipid Microdomain-Associated Signaling Events in Mast Cells

Felipe A. Lisboa, Ze Peng, Christian A. Combs, and Michael A. Beaven
J Immunol 2009 183: 5104-5112. Published online September 30, 2009; doi:10.4049/jimmunol.0802728 [Abstract] [Full Text] [PDF]  

Vascular Endothelial Growth Factor Is a Key Mediator in the Development of T Cell Priming and Its Polarization to Type 1 and Type 17 T Helper Cells in the Airways

You-Sun Kim, Sung-Wook Hong, Jun-Pyo Choi, Tae-Seop Shin, Hyung-Geun Moon, Eun-Jung Choi, Seong Gyu Jeon, Sun-Young Oh, Yong Song Gho, Zhou Zhu, and Yoon-Keun Kim
J Immunol 2009 183: 5113-5120. Published online September 28, 2009; doi:10.4049/jimmunol.0901566 [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Drosophila Glycoprotein 93 Is an Ortholog of Mammalian Heat Shock Protein gp96 (grp94, HSP90b1, HSPC4) and Retains Disulfide Bond-Independent Chaperone Function for TLRs and Integrins

Crystal Morales, Shuang Wu, Yi Yang, Bing Hao, and Zihai Li
J Immunol 2009 183: 5121-5128. Published online September 28, 2009; doi:10.4049/jimmunol.0900811 [Abstract] [Full Text] [PDF]  

Lymphoid Enhancer Binding Factor 1 Regulates Transcription through Gene Looping

Kangsun Yun, Jae-Seon So, Arijita Jash, and Sin-Hyeog Im
J Immunol 2009 183: 5129-5137. Published online September 25, 2009; doi:10.4049/jimmunol.0802744 [Abstract] [Full Text] [PDF] Data Supplement  

Novel Roles of Lysines 122, 125, and 58 in Functional Differences between Human and Murine MD-2

Jozica Vasl, Alja Oblak, Theresa L. Gioannini, Jerrold P. Weiss, and Roman Jerala
J Immunol 2009 183: 5138-5145. Published online September 25, 2009; doi:10.4049/jimmunol.0901544 [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Genetic Evidence That the Differential Expression of the Ligand-Independent Isoform of CTLA-4 Is the Molecular Basis of the Idd5.1 Type 1 Diabetes Region in Nonobese Diabetic Mice

Manabu Araki, Denise Chung, Sue Liu, Daniel B. Rainbow, Giselle Chamberlain, Valerie Garner, Kara M. D. Hunter, Lalitha Vijayakrishnan, Laurence B. Peterson, Mohamed Oukka, Arlene H. Sharpe, Raymond Sobel, Vijay K. Kuchroo, and Linda S. Wicker
J Immunol 2009 183: 5146-5157. Published online September 25, 2009; doi:10.4049/jimmunol.0802610 [Abstract] [Full Text] [PDF] Data Supplement  

A cis-Acting Regulatory Variant in the IL2RA Locus

Hui-Qi Qu, Dominique J. Verlaan, Bing Ge, Yang Lu, Kevin C. L. Lam, Rosemarie Grabs, Eef Harmsen, Thomas J. Hudson, Hakon Hakonarson, Tomi Pastinen, and Constantin Polychronakos
J Immunol 2009 183: 5158-5162. Published online September 30, 2009; doi:10.4049/jimmunol.0901337 [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

De Novo Recruitment of Antigen-Experienced and Naive T Cells Contributes to the Long-Term Maintenance of Antiviral T Cell Populations in the Persistently Infected Central Nervous System

Jingxian Zhao, Jincun Zhao, and Stanley Perlman
J Immunol 2009 183: 5163-5170. Published online September 28, 2009; doi:10.4049/jimmunol.0902164 [Abstract] [Full Text] [PDF]  

CCR7 Deficiency on Dendritic Cells Enhances Fungal Clearance in a Murine Model of Pulmonary Invasive Aspergillosis

Adam J. Hartigan, John Westwick, Gabor Jarai, and Cory M. Hogaboam
J Immunol 2009 183: 5171-5179. Published online September 25, 2009; doi:10.4049/jimmunol.0901027 [Abstract] [Full Text] [PDF]  

Essential Impact of NF-B Signaling on the H5N1 Influenza A Virus-Induced Transcriptome

Mirco Schmolke, Dorothee Viemann, Johannes Roth, and Stephan Ludwig
J Immunol 2009 183: 5180-5189. Published online September 28, 2009; doi:10.4049/jimmunol.0804198 [Abstract] [Full Text] [PDF] Data Supplement  

Binding of DC-HIL to Dermatophytic Fungi Induces Tyrosine Phosphorylation and Potentiates Antigen Presenting Cell Function

Jin-Sung Chung, Tatsuo Yudate, Mizuki Tomihari, Hideo Akiyoshi, Ponciano D. Cruz, Jr., and Kiyoshi Ariizumi
J Immunol 2009 183: 5190-5198. Published online September 30, 2009; doi:10.4049/jimmunol.0901319 [Abstract] [Full Text] [PDF]  

The Effects of Host Age on Follicular Dendritic Cell Status Dramatically Impair Scrapie Agent Neuroinvasion in Aged Mice

Karen L. Brown, Gwennaelle J. Wathne, Jill Sales, Moira E. Bruce, and Neil A. Mabbott
J Immunol 2009 183: 5199-5207. Published online September 28, 2009; doi:10.4049/jimmunol.0802695 [Abstract] [Full Text] [PDF] Data Supplement  

Pure Hemozoin Is Inflammatory In Vivo and Activates the NALP3 Inflammasome via Release of Uric Acid

Jason W. Griffith, Tiffany Sun, Michael T. McIntosh, and Richard Bucala
J Immunol 2009 183: 5208-5220. Published online September 25, 2009; doi:10.4049/jimmunol.0713552 [Abstract] [Full Text] [PDF]  

Identification of Mycobacterial -Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

Jeroen Geurtsen, Sunita Chedammi, Joram Mesters, Marlène Cot, Nicole N. Driessen, Tounkang Sambou, Ryo Kakutani, Roy Ummels, Janneke Maaskant, Hiroki Takata, Otto Baba, Tatsuo Terashima, Nicolai Bovin, Christina M. J. E. Vandenbroucke-Grauls, Jérôme Nigou, Germain Puzo, Anne Lemassu, Mamadou Daffé, and Ben J. Appelmelk
J Immunol 2009 183: 5221-5231. Published online September 25, 2009; doi:10.4049/jimmunol.0900768 [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Ethanol-Induced Expression of ET-1 and ET-BR in Liver Sinusoidal Endothelial Cells and Human Endothelial Cells Involves Hypoxia-Inducible Factor-1 and MicroRNA-199

Samantha Yeligar, Hidekazu Tsukamoto, and Vijay K. Kalra
J Immunol 2009 183: 5232-5243. Published online September 25, 2009; doi:10.4049/jimmunol.0901084 [Abstract] [Full Text] [PDF]  

Role of Endothelial TLR4 for Neutrophil Recruitment into Central Nervous System Microvessels in Systemic Inflammation

Hong Zhou, Graciela Andonegui, Connie H. Y. Wong, and Paul Kubes
J Immunol 2009 183: 5244-5250. Published online September 28, 2009; doi:10.4049/jimmunol.0901309 [Abstract] [Full Text] [PDF]  

Antigen-Induced Increases in Pulmonary Mast Cell Progenitor Numbers Depend on IL-9 and CD1d-Restricted NKT Cells

Tatiana G. Jones, Jenny Hallgren, Alison Humbles, Timothy Burwell, Fred D. Finkelman, Pilar Alcaide, K. Frank Austen, and Michael F. Gurish
J Immunol 2009 183: 5251-5260. Published online September 25, 2009; doi:10.4049/jimmunol.0901471 [Abstract] [Full Text] [PDF]  

IL-4R, a New Member that Associates with Syk Kinase: Implication in IL-4-Induced Human Neutrophil Functions

Jamila Ennaciri and Denis Girard
J Immunol 2009 183: 5261-5269. Published online September 25, 2009; doi:10.4049/jimmunol.0900109 [Abstract] [Full Text] [PDF]  

Prevention of Inflammatory Activation of Human Gestational Membranes in an Ex Vivo Model Using a Pharmacological NF-B Inhibitor

Jeffrey A. Keelan, Sadiqa Khan, Francisca Yosaatmadja, and Murray D. Mitchell
J Immunol 2009 183: 5270-5278. Published online September 25, 2009; doi:10.4049/jimmunol.0802660 [Abstract] [Full Text] [PDF] Data Supplement  

Recognition of Borrelia burgdorferi, the Lyme Disease Spirochete, by TLR7 and TLR9 Induces a Type I IFN Response by Human Immune Cells

Mary M. Petzke, Andrew Brooks, Michelle A. Krupna, Dana Mordue, and Ira Schwartz
J Immunol 2009 183: 5279-5292. Published online September 30, 2009; doi:10.4049/jimmunol.0901390 [Abstract] [Full Text] [PDF]  

Development of Allergen-Induced Airway Inflammation in the Absence of T-bet Regulation Is Dependent on IL-17

Douglas M. Durrant, Sarah L. Gaffen, Erik P. Riesenfeld, Charles G. Irvin, and Dennis W. Metzger
J Immunol 2009 183: 5293-5300. Published online September 25, 2009; doi:10.4049/jimmunol.0803109 [Abstract] [Full Text] [PDF] Data Supplement  

Critical Role of IL-17RA in Immunopathology of Influenza Infection

Christopher R. Crowe, Kong Chen, Derek A. Pociask, John F. Alcorn, Cameron Krivich, Richard I. Enelow, Ted M. Ross, Joseph L. Witztum, and Jay K. Kolls
J Immunol 2009 183: 5301-5310. Published online September 25, 2009; doi:10.4049/jimmunol.0900995 [Abstract] [Full Text] [PDF] Data Supplement  

Involvement of Innate and Adaptive Immunity in a Murine Model of Coronary Arteritis Mimicking Kawasaki Disease

Danica J. Schulte, Atilla Yilmaz, Kenichi Shimada, Michael C. Fishbein, Emily L. Lowe, Shuang Chen, Michelle Wong, Terence M. Doherty, Thomas Lehman, Timothy R. Crother, Rosalinda Sorrentino, and Moshe Arditi
J Immunol 2009 183: 5311-5318. Published online September 28, 2009; doi:10.4049/jimmunol.0901395 [Abstract] [Full Text] [PDF]  

Receptor-Mediated and Lectin-Like Activities of Carp (Cyprinus carpio) TNF-

Maria Forlenza, Stefan Magez, Jörn P. Scharsack, Adrie Westphal, Huub F. J. Savelkoul, and Geert F. Wiegertjes
J Immunol 2009 183: 5319-5332. Published online September 28, 2009; doi:10.4049/jimmunol.0901780 [Abstract] [Full Text] [PDF]  

Anti-Siglec-F Antibody Reduces Allergen-Induced Eosinophilic Inflammation and Airway Remodeling

Dae Jin Song, Jae Youn Cho, Sang Yeub Lee, Marina Miller, Peter Rosenthal, Pejman Soroosh, Michael Croft, Mai Zhang, Ajit Varki, and David H. Broide
J Immunol 2009 183: 5333-5341. Published online September 25, 2009; doi:10.4049/jimmunol.0801421 [Abstract] [Full Text] [PDF]  

Malaria-Induced Murine Pregnancy Failure: Distinct Roles for IFN- and TNF

Jayakumar S. Poovassery, Demba Sarr, Geoffrey Smith, Tamas Nagy, and Julie M. Moore
J Immunol 2009 183: 5342-5349. Published online September 25, 2009; doi:10.4049/jimmunol.0901669 [Abstract] [Full Text] [PDF]  

Role of TL1A in the Pathogenesis of Rheumatoid Arthritis

Jun Zhang, Xuehai Wang, Hassan Fahmi, Susan Wojcik, James Fikes, Youhua Yu, Jiangping Wu, and Hongyu Luo
J Immunol 2009 183: 5350-5357. Published online September 28, 2009; doi:10.4049/jimmunol.0802645 [Abstract] [Full Text] [PDF]  

MAIL Regulates Human Monocyte IL-6 Production

Sudarshan Seshadri, Yashaswini Kannan, Srabani Mitra, Jennifer Parker-Barnes, and Mark D. Wewers
J Immunol 2009 183: 5358-5368. Published online September 25, 2009; doi:10.4049/jimmunol.0802736 [Abstract] [Full Text] [PDF] Data Supplement  

FAN Stimulates TNF-Induced Gene Expression, Leukocyte Recruitment, and Humoral Response

Anne Montfort, Bénédicte de Badts, Victorine Douin-Echinard, Pascal G. P. Martin, Jason Iacovoni, Caroline Nevoit, Nicole Therville, Virginie Garcia, Marie-Antoinette Bertrand, Marie-Hélène Bessières, Marie-Claude Trombe, Thierry Levade, Hervé Benoist, and Bruno Ségui
J Immunol 2009 183: 5369-5378. Published online September 28, 2009; doi:10.4049/jimmunol.0803384 [Abstract] [Full Text] [PDF]  

Mitochondrial Dysfunction Increases Allergic Airway Inflammation

Leopoldo Aguilera-Aguirre, Attila Bacsi, Alfredo Saavedra-Molina, Alexander Kurosky, Sanjiv Sur, and Istvan Boldogh
J Immunol 2009 183: 5379-5387. Published online September 28, 2009; doi:10.4049/jimmunol.0900228 [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Enhanced Th2 Cell Differentiation and Allergen-Induced Airway Inflammation in Zfp35-Deficient Mice

Masayuki Kitajima, Chiaki Iwamura, Takako Miki-Hosokawa, Kenta Shinoda, Yusuke Endo, Yukiko Watanabe, Ryo Shinnakasu, Hiroyuki Hosokawa, Kahoko Hashimoto, Shinichiro Motohashi, Haruhiko Koseki, Osamu Ohara, Masakatsu Yamashita, and Toshinori Nakayama
J Immunol 2009 183: 5388-5396. Published online September 25, 2009; doi:10.4049/jimmunol.0804155 [Abstract] [Full Text] [PDF]  

Fine Structural Variations of βTCRs Selected by Vaccination with Natural versus Altered Self-Antigen in Melanoma Patients

Sébastien Wieckowski, Petra Baumgaertner, Patricia Corthesy, Verena Voelter, Pedro Romero, Daniel E. Speiser, and Nathalie Rufer
J Immunol 2009 183: 5397-5406. Published online September 28, 2009; doi:10.4049/jimmunol.0901460 [Abstract] [Full Text] [PDF] Data Supplement  

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