IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2007 178: 6673-6674. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Controlling the Ir Genes

Jeremy M. Boss
J Immunol 2007 178: 6675-6676. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Complementation Cloning of an MHC Class II Transactivator Mutated in Hereditary MHC Class II Deficiency (or Bare Lymphocyte Syndrome). Cell 1993. 75: 135–146.

Viktor Steimle, Luc A. Otten, Madeleine Zufferey, and Bernard Mach
J Immunol 2007 178: 6677-6688. [PDF]  

BRIEF REVIEWS:

Telomerase in T Lymphocytes: Use It and Lose It?

Arne N. Akbar and Milica Vukmanovic-Stejic
J Immunol 2007 178: 6689-6694. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: CNS CD11c⁺ Cells from Mice with Encephalomyelitis Polarize Th17 cells and Support CD25⁺CD4⁺ T cell-Mediated Immunosuppression, Suggesting Dual Roles in the Disease Process

Pratima Deshpande, Irah L. King, and Benjamin M. Segal
J Immunol 2007 178: 6695-6699. [Abstract] [Full Text] [PDF]  

Cutting Edge: Small Molecule CD40 Ligand Mimetics Promote Control of Parasitemia and Enhance T Cells Producing IFN- during Experimental Trypanosoma cruzi Infection

Mohammed Habib, Magali Noval Rivas, Mustapha Chamekh, Sébastien Wieckowski, Weimin Sun, Alberto Bianco, Nathalie Trouche, Olivier Chaloin, Hélène Dumortier, Michel Goldman, Gilles Guichard, Sylvie Fournel, and Bernard Vray
J Immunol 2007 178: 6700-6704. [Abstract] [Full Text] [PDF]  

Cutting Edge: Involvement of the Type I IFN Production and Signaling Pathway in Lipopolysaccharide-Induced IL-10 Production

Elmer Y. Chang, Beichu Guo, Sean E. Doyle, and Genhong Cheng
J Immunol 2007 178: 6705-6709. [Abstract] [Full Text] [PDF]  

Cutting Edge: Cross-Regulation by TLR4 and T cell Ig Mucin-3 Determines Sex Differences in Inflammatory Heart Disease

Sylvia Frisancho-Kiss, Sarah E. Davis, Jennifer F. Nyland, J. Augusto Frisancho, Daniela Cihakova, Masheka A. Barrett, Noel R. Rose, and DeLisa Fairweather
J Immunol 2007 178: 6710-6714. [Abstract] [Full Text] [PDF]  

Cutting Edge: TLR2 Directly Triggers Th1 Effector Functions

Takayuki Imanishi, Hiromitsu Hara, Shinobu Suzuki, Nobutaka Suzuki, Shizuo Akira, and Takashi Saito
J Immunol 2007 178: 6715-6719. [Abstract] [Full Text] [PDF]  

Cutting Edge: Direct Action of Thymic Stromal Lymphopoietin on Activated Human CD4⁺ T Cells

Irina Rochman, Norihiko Watanabe, Kazuhiko Arima, Yong-Jun Liu, and Warren J. Leonard
J Immunol 2007 178: 6720-6724. [Abstract] [Full Text] [PDF]  

Cutting Edge: Regulatory T Cells Induce CD4⁺CD25^–Foxp3^– T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-

LiLi Xu, Atsushi Kitani, Ivan Fuss, and Warren Strober
J Immunol 2007 178: 6725-6729. [Abstract] [Full Text] [PDF]  

Cutting Edge: Th17 and Regulatory T Cell Dynamics and the Regulation by IL-2 in the Tumor Microenvironment

Ilona Kryczek, Shuang Wei, Linhua Zou, Saleh Altuwaijri, Wojciech Szeliga, Jay Kolls, Alfred Chang, and Weiping Zou
J Immunol 2007 178: 6730-6733. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

An Essential Role for TNF in Modulating Thresholds for Survival, Activation, and Tolerance of CD8⁺ T Cells

Ioannis Chatzidakis, Georgia Fousteri, Debbie Tsoukatou, George Kollias, and Clio Mamalaki
J Immunol 2007 178: 6735-6745. [Abstract] [Full Text] [PDF]  

Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike

Anne Wilson, Denis-Luc Ardiet, Catherine Saner, Nathalie Vilain, Friedrich Beermann, Michel Aguet, H. Robson MacDonald, and Olav Zilian
J Immunol 2007 178: 6746-6751. [Abstract] [Full Text] [PDF]  

Signal 3 Availability Limits the CD8 T Cell Response to a Solid Tumor

Julie M. Curtsinger, Michael Y. Gerner, Debra C. Lins, and Matthew F. Mescher
J Immunol 2007 178: 6752-6760. [Abstract] [Full Text] [PDF]  

Comparative Prime-Boost Vaccinations Using Semliki Forest Virus, Adenovirus, and ALVAC Vectors Demonstrate Differences in the Generation of a Protective Central Memory CTL Response against the P815 Tumor

Tanja I. Näslund, Catherine Uyttenhove, Eva K. L. Nordström, Didier Colau, Guy Warnier, Mikael Jondal, Benoît J. Van den Eynde, and Peter Liljeström
J Immunol 2007 178: 6761-6769. [Abstract] [Full Text] [PDF]  

Lack of Essential Role of NF-B p50, RelA, and cRel Subunits in Virus-Induced Type 1 IFN Expression

Xingyu Wang, Sofia Hussain, Emilie-Jeanne Wang, Xiuyan Wang, Ming O. Li, Adolfo García-Sastre, and Amer A. Beg
J Immunol 2007 178: 6770-6776. [Abstract] [Full Text] [PDF]  

Distinct Roles of Different NF-B Subunits in Regulating Inflammatory and T Cell Stimulatory Gene Expression in Dendritic Cells

Junmei Wang, Xingyu Wang, Sofia Hussain, Ye Zheng, Shomyseh Sanjabi, Fatah Ouaaz, and Amer A. Beg
J Immunol 2007 178: 6777-6788. [Abstract] [Full Text] [PDF]  

Detection and Long-Term In Vivo Monitoring of Individual Tumor-Specific T Cell Clones in Patients with Metastatic Melanoma

Jaroslav Michalek, Ivo Kocak, Vuk Fait, Jan Zaloudik, and Roman Hajek
J Immunol 2007 178: 6789-6795. [Abstract] [Full Text] [PDF]  

Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival

John H. Carter, Juliet M. Lefebvre, David L. Wiest, and Warren G. Tourtellotte
J Immunol 2007 178: 6796-6805. [Abstract] [Full Text] [PDF] Data Supplement  

Th17 Augmentation in OTII TCR Plus T Cell-Selective Type 1 Sphingosine 1-Phosphate Receptor Double Transgenic Mice

Mei-Chuan Huang, Susan R. Watson, Jia-Jun Liao, and Edward J. Goetzl
J Immunol 2007 178: 6806-6813. [Abstract] [Full Text] [PDF]  

Vaccinia Virus-Specific CD4⁺ T Cell Responses Target a Set of Antigens Largely Distinct from Those Targeted by CD8⁺ T Cell Responses

Magdalini Moutaftsi, Huynh-Hoa Bui, Bjoern Peters, John Sidney, Shahram Salek-Ardakani, Carla Oseroff, Valerie Pasquetto, Shane Crotty, Michael Croft, Elliot J. Lefkowitz, Howard Grey, and Alessandro Sette
J Immunol 2007 178: 6814-6820. [Abstract] [Full Text] [PDF] Data Supplement  

Human CD5 Protects Circulating Tumor Antigen-Specific CTL from Tumor-Mediated Activation-Induced Cell Death

Grzegorz Friedlein, Faten El Hage, Isabelle Vergnon, Catherine Richon, Patrick Saulnier, Yann Lécluse, Anne Caignard, Laurence Boumsell, Georges Bismuth, Salem Chouaib, and Fathia Mami-Chouaib
J Immunol 2007 178: 6821-6827. [Abstract] [Full Text] [PDF]  

Regulation of Cell Adhesion by Affinity and Conformational Unbending of ₄₁ Integrin

Alexandre Chigaev, Anna Waller, Gordon J. Zwartz, Tione Buranda, and Larry A. Sklar
J Immunol 2007 178: 6828-6839. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ T Regulatory Cells Dominate Multiple Immune Evasion Mechanisms in Early but Not Late Phases of Tumor Development in a B Cell Lymphoma Model

Kutlu G. Elpek, Chantale Lacelle, Narendra P. Singh, Esma S. Yolcu, and Haval Shirwan
J Immunol 2007 178: 6840-6848. [Abstract] [Full Text] [PDF]  

Induction of Tolerance in CD8⁺ T Cells to a Transgenic Autoantigen Expressed in the Liver Does Not Require Cross-Presentation

Junko Morimoto, Xiaoxio Tan, Ryan M. Teague, Claes Öhlén, and Philip D. Greenberg
J Immunol 2007 178: 6849-6860. [Abstract] [Full Text] [PDF]  

CD103^– and CD103⁺ Bronchial Lymph Node Dendritic Cells Are Specialized in Presenting and Cross-Presenting Innocuous Antigen to CD4⁺ and CD8⁺ T Cells

Maria-Luisa del Rio, Jose-Ignacio Rodriguez-Barbosa, Elisabeth Kremmer, and Reinhold Förster
J Immunol 2007 178: 6861-6866. [Abstract] [Full Text] [PDF]  

Tumor Exosomes Inhibit Differentiation of Bone Marrow Dendritic Cells

Shaohua Yu, Cunren Liu, Kaihong Su, Jianhua Wang, Yuelong Liu, Liming Zhang, Chuanyu Li, Yingzi Cong, Robert Kimberly, William E. Grizzle, Carla Falkson, and Huang-Ge Zhang
J Immunol 2007 178: 6867-6875. [Abstract] [Full Text] [PDF]  

Murine Dendritic Cell Type I IFN Production Induced by Human IgG-RNA Immune Complexes Is IFN Regulatory Factor (IRF)5 and IRF7 Dependent and Is Required for IL-6 Production

Kei Yasuda, Christophe Richez, Joseph W. Maciaszek, Neerja Agrawal, Shizuo Akira, Ann Marshak-Rothstein, and Ian R. Rifkin
J Immunol 2007 178: 6876-6885. [Abstract] [Full Text] [PDF]  

Type 2 Diabetes Impairs Insulin Receptor Substrate-2-Mediated Phosphatidylinositol 3-Kinase Activity in Primary Macrophages to Induce a State of Cytokine Resistance to IL-4 in Association with Overexpression of Suppressor of Cytokine Signaling-3

Jason C. O’Connor, Christina L. Sherry, Christopher B. Guest, and Gregory G. Freund
J Immunol 2007 178: 6886-6893. [Abstract] [Full Text] [PDF]  

The CD28/CTLA-4-B7 Signaling Pathway Is Involved in Both Allergic Sensitization and Tolerance Induction to Orally Administered Peanut Proteins

Femke van Wijk, Stefan Nierkens, Wilco de Jong, Ellen J. M. Wehrens, Louis Boon, Peter van Kooten, Léon M. J. Knippels, and Raymond Pieters
J Immunol 2007 178: 6894-6900. [Abstract] [Full Text] [PDF]  

Distinct Subsets of FoxP3⁺ Regulatory T Cells Participate in the Control of Immune Responses

Geoffrey L. Stephens, John Andersson, and Ethan M. Shevach
J Immunol 2007 178: 6901-6911. [Abstract] [Full Text] [PDF]  

Altered Innate Immune Functioning of Dendritic Cells in Elderly Humans: A Role of Phosphoinositide 3-Kinase-Signaling Pathway

Anshu Agrawal, Sudhanshu Agrawal, Jia-Ning Cao, Houfen Su, Kathryn Osann, and Sudhir Gupta
J Immunol 2007 178: 6912-6922. [Abstract] [Full Text] [PDF]  

Analysis of the Role of Bleomycin Hydrolase in Antigen Presentation and the Generation of CD8 T Cell Responses

Charles F. Towne, Ian A. York, Levi B. Watkin, John S. Lazo, and Kenneth L. Rock
J Immunol 2007 178: 6923-6930. [Abstract] [Full Text] [PDF]  

Human Resting CD4⁺ T Cells Are Constitutively Inhibited by TGF under Steady-State Conditions

Sabine Classen, Thomas Zander, Daniela Eggle, Jens M. Chemnitz, Benedikt Brors, Ingrid Büchmann, Alexey Popov, Marc Beyer, Roland Eils, Svenja Debey, and Joachim L. Schultze
J Immunol 2007 178: 6931-6940. [Abstract] [Full Text] [PDF]  

p300 Protein Acetyltransferase Activity Suppresses Systemic Lupus Erythematosus-Like Autoimmune Disease in Mice

Nicole Forster, Sven Gallinat, Jadwiga Jablonska, Siegfried Weiss, Hans-Peter Elsässer, and Werner Lutz
J Immunol 2007 178: 6941-6948. [Abstract] [Full Text] [PDF]  

Functional Gap Junctions Facilitate Melanoma Antigen Transfer and Cross-Presentation between Human Dendritic Cells

Ariadna Mendoza-Naranjo, Pablo J. Saéz, C. Christian Johansson, Marcos Ramírez, Dinka Mandakovic, Cristian Pereda, Mercedes N. López, Rolf Kiessling, Juan C. Sáez, and Flavio Salazar-Onfray
J Immunol 2007 178: 6949-6957. [Abstract] [Full Text] [PDF]  

Parallel Loss of Myeloid and Plasmacytoid Dendritic Cells from Blood and Lymphoid Tissue in Simian AIDS

Kevin N. Brown, Anita Trichel, and Simon M. Barratt-Boyes
J Immunol 2007 178: 6958-6967. [Abstract] [Full Text] [PDF]  

Role for CD21 in the Establishment of an Extracellular HIV Reservoir in Lymphoid Tissues

Jason Ho, Susan Moir, Liudmila Kulik, Angela Malaspina, Eileen T. Donoghue, Natalie J. Miller, Wei Wang, Tae-Wook Chun, Anthony S. Fauci, and V. Michael Holers
J Immunol 2007 178: 6968-6974. [Abstract] [Full Text] [PDF]  

CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue

Elizabeth Connick, Teresa Mattila, Joy M. Folkvord, Rick Schlichtemeier, Amie L. Meditz, M. Graham Ray, Martin D. McCarter, Samantha MaWhinney, Aaron Hage, Cara White, and Pamela J. Skinner
J Immunol 2007 178: 6975-6983. [Abstract] [Full Text] [PDF]  

Cytopiloyne, a Polyacetylenic Glucoside, Prevents Type 1 Diabetes in Nonobese Diabetic Mice

Cicero Lee-Tian Chang, Shu-Lin Chang, Yi-Mei Lee, Yi-Ming Chiang, Da-Yung Chuang, Hui-Kai Kuo, and Wen-Chin Yang
J Immunol 2007 178: 6984-6993. [Abstract] [Full Text] [PDF]  

Role of Thrombospondin-1 in T Cell Response to Ocular Pigment Epithelial Cells

Yuri Futagami, Sunao Sugita, Jose Vega, Kazuhiro Ishida, Hiroshi Takase, Kazuichi Maruyama, Hiroyuki Aburatani, and Manabu Mochizuki
J Immunol 2007 178: 6994-7005. [Abstract] [Full Text] [PDF]  

In Vivo Signaling through the Neurokinin 1 Receptor Favors Transgene Expression by Langerhans Cells and Promotes the Generation of Th1- and Tc1-Biased Immune Responses

Alicia R. Mathers, Olga A. Tckacheva, Brian M. Janelsins, William J. Shufesky, Adrian E. Morelli, and Adriana T. Larregina
J Immunol 2007 178: 7006-7017. [Abstract] [Full Text] [PDF]  

Rapamycin-Conditioned Dendritic Cells Are Poor Stimulators of Allogeneic CD4⁺ T Cells, but Enrich for Antigen-Specific Foxp3⁺ T Regulatory Cells and Promote Organ Transplant Tolerance

Heth R. Turnquist, Giorgio Raimondi, Alan F. Zahorchak, Ryan T. Fischer, Zhiliang Wang, and Angus W. Thomson
J Immunol 2007 178: 7018-7031. [Abstract] [Full Text] [PDF]  

Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4⁺ T Cells

Jamie Wong, Reinhard Obst, Margarida Correia-Neves, Grigoriy Losyev, Diane Mathis, and Christophe Benoist
J Immunol 2007 178: 7032-7041. [Abstract] [Full Text] [PDF] Data Supplement  

Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-Deficient Mice

Yoshitaka Taketomi, Kohei Sunaga, Satoshi Tanaka, Masanori Nakamura, Satoru Arata, Tomohiko Okuda, Tae-Chul Moon, Hyeun-Wook Chang, Yukihiko Sugimoto, Koichi Kokame, Toshiyuki Miyata, Makoto Murakami, and Ichiro Kudo
J Immunol 2007 178: 7042-7053. [Abstract] [Full Text] [PDF]  

Plasmodium berghei-Infected Primary Hepatocytes Process and Present the Circumsporozoite Protein to Specific CD8⁺ T Cells In Vitro

Silayuv E. Bongfen, Ralph Torgler, Jackeline F. Romero, Laurent Renia, and Giampietro Corradin
J Immunol 2007 178: 7054-7063. [Abstract] [Full Text] [PDF]  

The Tick Salivary Protein, Salp15, Inhibits the Development of Experimental Asthma

Sara A. Paveglio, Jenna Allard, Jana Mayette, Laurie A. Whittaker, Ignacio Juncadella, Juan Anguita, and Matthew E. Poynter
J Immunol 2007 178: 7064-7071. [Abstract] [Full Text] [PDF]  

C57BL/6 Mice Genetically Deficient in IL-12/IL-23 and IFN- Are Susceptible to Experimental Autoimmune Myasthenia Gravis, Suggesting a Pathogenic Role of Non-Th1 Cells

Wei Wang, Monica Milani, Norma Ostlie, David Okita, Rajeev K. Agarwal, Rachel Caspi, and Bianca M. Conti-Fine
J Immunol 2007 178: 7072-7080. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Interaction of PRP4 with Krüppel-Like Factor 13 Regulates CCL5 Transcription

Boli Huang, Yong-Tae Ahn, Lisa McPherson, Carol Clayberger, and Alan M. Krensky
J Immunol 2007 178: 7081-7087. [Abstract] [Full Text] [PDF]  

Down-Regulation of the SWI/SNF Chromatin Remodeling Activity by TCR Signaling Is Required for Proper Thymocyte Maturation

Kyoo Y. Lee, Young I. Choi, Jieun Kim, Jin W. Choi, Dong H. Sohn, Changjin Lee, Sung H. Jeon, and Rho H. Seong
J Immunol 2007 178: 7088-7096. [Abstract] [Full Text] [PDF]  

Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-B Transcription Factor c-Rel

Karen Bunting, Sudha Rao, Kristine Hardy, Donna Woltring, Gareth S. Denyer, Jun Wang, Steve Gerondakis, and M. Frances Shannon
J Immunol 2007 178: 7097-7109. [Abstract] [Full Text] [PDF] Data Supplement  

The Central Leucine-Rich Repeat Region of Chicken TLR16 Dictates Unique Ligand Specificity and Species-Specific Interaction with TLR2

A. Marijke Keestra, Marcel R. de Zoete, Rémon A. M. H. van Aubel, and Jos P. M. van Putten
J Immunol 2007 178: 7110-7119. [Abstract] [Full Text] [PDF]  

Novel Engineered Trastuzumab Conformational Epitopes Demonstrate In Vitro and In Vivo Antitumor Properties against HER-2/neu

Joan T. Garrett, Sharad Rawale, Stephanie D. Allen, Gary Phillips, Guido Forni, John C. Morris, and Pravin T. P. Kaumaya
J Immunol 2007 178: 7120-7131. [Abstract] [Full Text] [PDF]  

The Neutralization Properties of a HIV-Specific Antibody Are Markedly Altered by Glycosylation Events Outside the Antigen-Binding Domain

Luis R. Miranda, Mark Duval, Heather Doherty, Michael S. Seaman, Marshall R. Posner, and Lisa A. Cavacini
J Immunol 2007 178: 7132-7138. [Abstract] [Full Text] [PDF]  

Defining In Vivo Transcription Factor Complexes of the Murine CD21 and CD23 Genes

Irina Debnath, Kirstin M. Roundy, Janis J. Weis, and John H. Weis
J Immunol 2007 178: 7139-7150. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Genomics and Diversity of the Common Marmoset Monkey NK Complex

Anne Averdam, Heiner Kuhl, Mario Sontag, Tamara Becker, Austin L. Hughes, Richard Reinhardt, and Lutz Walter
J Immunol 2007 178: 7151-7161. [Abstract] [Full Text] [PDF] Data Supplement  

Extended Gene Map Reveals Tripartite Motif, C-Type Lectin, and Ig Superfamily Type Genes within a Subregion of the Chicken MHC-B Affecting Infectious Disease

Takashi Shiina, W. Elwood Briles, Ronald M. Goto, Kazuyoshi Hosomichi, Kazuyo Yanagiya, Sayoko Shimizu, Hidetoshi Inoko, and Marcia M. Miller
J Immunol 2007 178: 7162-7172. [Abstract] [Full Text] [PDF]  

The Autoimmune Regulator Directly Controls the Expression of Genes Critical for Thymic Epithelial Function

Qing-Guo Ruan, Kenneth Tung, Daniel Eisenman, Yulius Setiady, Sarah Eckenrode, Bing Yi, Sharad Purohit, Wei-Peng Zheng, Yan Zhang, Leena Peltonen, and Jin-Xiong She
J Immunol 2007 178: 7173-7180. [Abstract] [Full Text] [PDF]  

Cooperativity of Hydrophobic Anchor Interactions: Evidence for Epitope Selection by MHC Class II as a Folding Process

Andrea Ferrante and Jack Gorski
J Immunol 2007 178: 7181-7189. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

IFN-- and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-37

Adrian R. Martineau, Katalin A. Wilkinson, Sandra M. Newton, R. Andres Floto, Anthony W. Norman, Keira Skolimowska, Robert N. Davidson, Ole E. Sørensen, Beate Kampmann, Christopher J. Griffiths, and Robert J. Wilkinson
J Immunol 2007 178: 7190-7198. [Abstract] [Full Text] [PDF]  

Tubulation of Class II MHC Compartments Is Microtubule Dependent and Involves Multiple Endolysosomal Membrane Proteins in Primary Dendritic Cells

Jatin M. Vyas, You-Me Kim, Katerina Artavanis-Tsakonas, J. Christopher Love, Annemarthe G. Van der Veen, and Hidde L. Ploegh
J Immunol 2007 178: 7199-7210. [Abstract] [Full Text] [PDF]  

A Novel Functional CTL Avidity/Activity Compartmentalization to the Site of Mucosal Immunization Contributes to Protection of Macaques against Simian/Human Immunodeficiency Viral Depletion of Mucosal CD4⁺ T Cells

Igor M. Belyakov, Dmitry Isakov, Qing Zhu, Amiran Dzutsev, and Jay A. Berzofsky
J Immunol 2007 178: 7211-7221. [Abstract] [Full Text] [PDF]  

B Cells Moderate Inflammatory Progression and Enhance Bacterial Containment upon Pulmonary Challenge with Mycobacterium tuberculosis

Paul J. Maglione, Jiayong Xu, and John Chan
J Immunol 2007 178: 7222-7234. [Abstract] [Full Text] [PDF]  

Viral Interference with Antigen Presentation Does Not Alter Acute or Chronic CD8 T Cell Immunodominance in Murine Cytomegalovirus Infection

Michael W. Munks, Amelia K. Pinto, Carmen M. Doom, and Ann B. Hill
J Immunol 2007 178: 7235-7241. [Abstract] [Full Text] [PDF]  

Biphasic Effect of Gingipains from Porphyromonas gingivalis on the Human Complement System

Katarzyna Popadiak, Jan Potempa, Kristian Riesbeck, and Anna M. Blom
J Immunol 2007 178: 7242-7250. [Abstract] [Full Text] [PDF]  

Dendritic Cell-Derived IL-12p40 Homodimer Contributes to Susceptibility in Cutaneous Leishmaniasis in BALB/c Mice

Axel P. Nigg, Sabine Zahn, Dominik Rückerl, Christoph Hölscher, Takayuki Yoshimoto, Jan M. Ehrchen, Florian Wölbing, Mark C. Udey, and Esther von Stebut
J Immunol 2007 178: 7251-7258. [Abstract] [Full Text] [PDF]  

STAT1 Expression in Dendritic Cells, but Not T Cells, Is Required for Immunity to Leishmania major

Leanne M. Johnson and Phillip Scott
J Immunol 2007 178: 7259-7266. [Abstract] [Full Text] [PDF]  

Early Virus-Associated Bystander Events Affect the Fitness of the CD8 T Cell Response to Persistent Virus Infection

Nicolas P. Andrews, Christopher D. Pack, Vaiva Vezys, Glen N. Barber, and Aron E. Lukacher
J Immunol 2007 178: 7267-7275. [Abstract] [Full Text] [PDF]  

Integrin Engagement Mediates the Human Polymorphonuclear Leukocyte Response to a Fungal Pathogen-Associated Molecular Pattern

Liz M. Lavigne, Xian M. O’Brien, Minsoo Kim, Jessie W. Janowski, Jorge E. Albina, and Jonathan S. Reichner
J Immunol 2007 178: 7276-7282. [Abstract] [Full Text] [PDF]  

C-Reactive Protein Enhances Immunity to Streptococcus pneumoniae by Targeting Uptake to FcR on Dendritic Cells

Deirdre Thomas-Rudolph, Terry W. Du Clos, Clifford M. Snapper, and Carolyn Mold
J Immunol 2007 178: 7283-7291. [Abstract] [Full Text] [PDF]  

Dual Binding Specificity of a Borrelia hermsii-Associated Complement Regulator-Acquiring Surface Protein for Factor H and Plasminogen Discloses a Putative Virulence Factor of Relapsing Fever Spirochetes

Evelyn Rossmann, Peter Kraiczy, Pia Herzberger, Christine Skerka, Michael Kirschfink, Markus M. Simon, Peter F. Zipfel, and Reinhard Wallich
J Immunol 2007 178: 7292-7301. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

A Novel RBP-J-Dependent Switch from C/EBP to C/EBP at the C/EBP Binding Site on the C-Reactive Protein Promoter

Prem Prakash Singh, Bhavya Voleti, and Alok Agrawal
J Immunol 2007 178: 7302-7309. [Abstract] [Full Text] [PDF]  

Inhibition of Allergen-Induced Airway Remodeling in Smad 3-Deficient Mice

Annie V. Le, Jae Youn Cho, Marina Miller, Shauna McElwain, Kirsti Golgotiu, and David H. Broide
J Immunol 2007 178: 7310-7316. [Abstract] [Full Text] [PDF]  

Protection against Myocardial Ischemia/Reperfusion Injury in TLR4-Deficient Mice Is Mediated through a Phosphoinositide 3-Kinase-Dependent Mechanism

Fang Hua, Tuanzhu Ha, Jing Ma, Yan Li, Jim Kelley, Xiang Gao, I. William Browder, Race L. Kao, David L. Williams, and Chuanfu Li
J Immunol 2007 178: 7317-7324. [Abstract] [Full Text] [PDF]  

Soluble TNF-Like Cytokine (TL1A) Production by Immune Complexes Stimulated Monocytes in Rheumatoid Arthritis

Marco A. Cassatella, Gabriela Pereira da Silva, Ilaria Tinazzi, Fabio Facchetti, Patrizia Scapini, Federica Calzetti, Nicola Tamassia, Ping Wei, Bernardetta Nardelli, Viktor Roschke, Annunciata Vecchi, Alberto Mantovani, Lisa M. Bambara, Steven W. Edwards, and Antonio Carletto
J Immunol 2007 178: 7325-7333. [Abstract] [Full Text] [PDF]  

A Peroxynitrite-Dependent Pathway Is Responsible for Blood-Brain Barrier Permeability Changes during a Central Nervous System Inflammatory Response: TNF- Is Neither Necessary nor Sufficient

Timothy W. Phares, Marzena J. Fabis, Christine M. Brimer, Rhonda B. Kean, and D. Craig Hooper
J Immunol 2007 178: 7334-7343. [Abstract] [Full Text] [PDF]  

The MYD88-Independent Pathway Is Not Mobilized in Human Neutrophils Stimulated via TLR4

Nicola Tamassia, Vincent Le Moigne, Federica Calzetti, Marta Donini, Sara Gasperini, Thornin Ear, Alexandre Cloutier, Fernando O. Martinez, Marco Fabbri, Massimo Locati, Alberto Mantovani, Patrick P. McDonald, and Marco A. Cassatella
J Immunol 2007 178: 7344-7356. [Abstract] [Full Text] [PDF]  

Inactivation of Cdc42 Is Necessary for Depolymerization of Phagosomal F-Actin and Subsequent Phagosomal Maturation

Maria Lerm, Veronika Patcha Brodin, Iida Ruishalme, Olle Stendahl, and Eva Särndahl
J Immunol 2007 178: 7357-7365. [Abstract] [Full Text] [PDF] Data Supplement  

Corticosteroid Inhibition of Growth-Related Oncogene Protein- via Mitogen-Activated Kinase Phosphatase-1 in Airway Smooth Muscle Cells

Razao Issa, Shaoping Xie, Nadia Khorasani, Maria Sukkar, Ian M. Adcock, Kang-Yun Lee, and Kian Fan Chung
J Immunol 2007 178: 7366-7375. [Abstract] [Full Text] [PDF]  

Nuclear Heat Shock Protein 72 as a Negative Regulator of Oxidative Stress (Hydrogen Peroxide)-Induced HMGB1 Cytoplasmic Translocation and Release

Daolin Tang, Rui Kang, Weimin Xiao, Lei Jiang, Meidong Liu, Yongzhong Shi, Kangkai Wang, Haichao Wang, and Xianzhong Xiao
J Immunol 2007 178: 7376-7384. [Abstract] [Full Text] [PDF]  

IFN- Protects Cerulein-Induced Acute Pancreatitis by Repressing NF-B Activation

Takahito Hayashi, Yuko Ishida, Akihiko Kimura, Yoichiro Iwakura, Naofumi Mukaida, and Toshikazu Kondo
J Immunol 2007 178: 7385-7394. [Abstract] [Full Text] [PDF]  

Proinflammatory Proteases Liberate a Discrete High-Affinity Functional FPRL1 (CCR12) Ligand from CCL23

Zhenhua Miao, Brett A. Premack, Zheng Wei, Yu Wang, Craig Gerard, Henry Showell, Maureen Howard, Thomas J. Schall, and Robert Berahovich
J Immunol 2007 178: 7395-7404. [Abstract] [Full Text] [PDF]  

Expression of Tie-2 by Human Monocytes and Their Responses to Angiopoietin-2

Craig Murdoch, Simon Tazzyman, Steve Webster, and Claire E. Lewis
J Immunol 2007 178: 7405-7411. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Tubulin Is a Neuronal Target of Autoantibodies in Sydenham’s Chorea

Christine A. Kirvan, Carol J. Cox, Susan E. Swedo, and Madeleine W. Cunningham
J Immunol 2007 178: 7412-7421. [Abstract] [Full Text] [PDF]  

Abrogation of Lupus Nephritis in Activation-Induced Deaminase-Deficient MRL/lpr Mice

Chuancang Jiang, Julie Foley, Natasha Clayton, Grace Kissling, Micheal Jokinen, Ronald Herbert, and Marilyn Diaz
J Immunol 2007 178: 7422-7431. [Abstract] [Full Text] [PDF]  

Soluble Ig-Like Transcript 3 Inhibits Tumor Allograft Rejection in Humanized SCID Mice and T Cell Responses in Cancer Patients

Nicole Suciu-Foca, Nikki Feirt, Qing-Yin Zhang, George Vlad, Zhuoru Liu, Hana Lin, Chih-Chao Chang, Eric K. Ho, Adriana I. Colovai, Howard Kaufman, Vivette D. D’Agati, Harshwardhan M. Thaker, Helen Remotti, Sara Galluzzo, Paola Cinti, Carla Rabitti, John Allendorf, John Chabot, Marco Caricato, Roberto Coppola, Pasquale Berloco, and Raffaello Cortesini
J Immunol 2007 178: 7432-7441. [Abstract] [Full Text] [PDF]  

Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients

Asifa S. Haider, Michelle A. Lowes, Humphrey Gardner, Raj Bandaru, Kamruz Darabi, Francesca Chamian, Toyoko Kikuchi, Patricia Gilleaudeau, Mary S. Whalen, Irma Cardinale, Inna Novitskaya, and James G. Krueger
J Immunol 2007 178: 7442-7449. [Abstract] [Full Text] [PDF] Data Supplement  

A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF- Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis

Gunther Spohn, Reto Guler, Pål Johansen, Iris Keller, Muazzam Jacobs, Markus Beck, Franziska Rohner, Monika Bauer, Klaus Dietmeier, Thomas M. Kündig, Gary T. Jennings, Frank Brombacher, and Martin F. Bachmann
J Immunol 2007 178: 7450-7457. [Abstract] [Full Text] [PDF]  

Immunization of HLA Class I Transgenic Mice Identifies Autoantigenic Epitopes Eliciting Dominant Responses in Type 1 Diabetes Patients

Philippe Blancou, Roberto Mallone, Emanuela Martinuzzi, Sabine Sévère, Sylvie Pogu, Giulia Novelli, Graziella Bruno, Bernard Charbonnel, Manuel Dolz, Lucy Chaillous, Peter van Endert, and Jean-Marie Bach
J Immunol 2007 178: 7458-7466. [Abstract] [Full Text] [PDF]  

Comparing ELISA and Surface Plasmon Resonance for Assessing Clinical Immunogenicity of Panitumumab

James A. Lofgren, Sripriya Dhandapani, Jason J. Pennucci, Christina M. Abbott, Daniel T. Mytych, Arunan Kaliyaperumal, Steven J. Swanson, and Michael C. Mullenix
J Immunol 2007 178: 7467-7472. [Abstract] [Full Text] [PDF]  

Enhanced Immune Reconstitution by Sex Steroid Ablation following Allogeneic Hemopoietic Stem Cell Transplantation

Gabrielle L. Goldberg, Önder Alpdogan, Stephanie J. Muriglan, Maree V. Hammett, Morag K. Milton, Jeffrey M. Eng, Vanessa M. Hubbard, Adam Kochman, Lucy M. Willis, Andrew S. Greenberg, Kartono H. Tjoe, Jayne S. Sutherland, Ann Chidgey, Marcel R. M. van den Brink, and Richard L. Boyd
J Immunol 2007 178: 7473-7484. [Abstract] [Full Text] [PDF]  

CORRECTIONS:

Human mAbs to Pseudomonas aeruginosa alginate that protect against infection by both mucoid and nonmucoid strains.

G. B. Pier, D. Boyer, M. Preston, F. T. Coleman, N. Llosa, S. Mueschenborn-Koglin, C. Theilacker, H. Goldenberg, J. Uchin, G. P. Priebe, M. Grout, M. Posner, and L. Cavacini
J Immunol 2007 178: 7485. [Full Text] [PDF]  

TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis

H. J. Brown, H. R. Lock, S. H. Sacks, and M. G. Robson
J Immunol 2007 178: 7485. [Full Text] [PDF]  

Induced expression of murine 2a by CD40 ligation independently of IFN-

J. T. Collins, J. Shi, B. E. Burrell, D. K. Bishop, and W. A. Dunnick
J Immunol 2007 178: 7486. [Full Text] [PDF]  

Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs

I.-J. Kim, C. E. Burkum, T. Cookenham, P. L. Schwartzberg, D. L. Woodland, and M. A. Blackman
J Immunol 2007 178: 7487. [Full Text] [PDF]  

The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis

S. M. Sa, P. A. Valdez, J. Wu, K. Jung, F. Zhong, L. Hall, I. Kasman, J. Winer, Z. Modrusan, D. M. Danilenko, and W. Ouyang
J Immunol 2007 178: 7487. [Full Text] [PDF]  

Human CD4⁺CD25^low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance

Q. Xu, J. Lee, E. Jankowska-Gan, J. Schultz, D. A. Roennburg, L. D. Haynes, S. Kusaka, H. W. Sollinger, S. J. Knechtle, A. M. VanBuskirk, J. R. Torrealba, and W. J. Burlingham
J Immunol 2007 178: 7488. [Full Text] [PDF]  

An essential role for IL-18 in CD8 T cell-mediated suppression of IgE responses

M. Salagianni, W. K. Loon, M. J. Thomas, A. Noble, and D. M. Kemeny
J Immunol 2007 178: 7488. [Full Text] [PDF]  

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