IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2006 177: 4233-4234. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

Antibody Wars: Extreme Diversity

Patricia J. Gearhart
J Immunol 2006 177: 4235-4236. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Origin of Antibody Variation. Nature 1966. 211: 242–243.

Sydney Brenner and César Milstein
J Immunol 2006 177: 4237-4238. [PDF]  

BRIEF REVIEWS:

The Inflammatory Caspases: Key Players in the Host Response to Pathogenic Invasion and Sepsis

Amal Nadiri, Melissa K. Wolinski, and Maya Saleh
J Immunol 2006 177: 4239-4245. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: IL-7-Independent Regulation of IL-7 Receptor Expression and Memory CD8 T Cell Development

Kimberly D. Klonowski, Kristina J. Williams, Amanda L. Marzo, and Leo Lefrançois
J Immunol 2006 177: 4247-4251. [Abstract] [Full Text] [PDF]  

Cutting Edge: ASC Mediates the Induction of Multiple Cytokines by Porphyromonas gingivalis via Caspase-1-Dependent and -Independent Pathways

Debra J. Taxman, Jinghua Zhang, Catherine Champagne, Daniel T. Bergstralh, Heather A. Iocca, John D. Lich, and Jenny Pan-Yun Ting
J Immunol 2006 177: 4252-4256. [Abstract] [Full Text] [PDF]  

Cutting Edge: Paracrine, but Not Autocrine, IL-2 Signaling Is Sustained during Early Antiviral CD4 T Cell Response

Meixiao Long and Adam J. Adler
J Immunol 2006 177: 4257-4261. [Abstract] [Full Text] [PDF]  

Cutting Edge: T Cell Requirement for CD28 Costimulation Is Due to Negative Regulation of TCR Signals by PTEN

Jodi L. Buckler, Patrick T. Walsh, Paige M. Porrett, Yongwon Choi, and Laurence A. Turka
J Immunol 2006 177: 4262-4266. [Abstract] [Full Text] [PDF]  

Cutting Edge: IL-1 Mediates the Proangiogenic Activity of Osteopontin-Activated Human Monocytes

Antonella Naldini, Daria Leali, Annalisa Pucci, Emilia Morena, Fabio Carraro, Beatrice Nico, Domenico Ribatti, and Marco Presta
J Immunol 2006 177: 4267-4270. [Abstract] [Full Text] [PDF]  

Cutting Edge: Rho Activation and Actin Polarization Are Dependent on Plexin-A1 in Dendritic Cells

So-Young Eun, Brian P. O’Connor, Athena W. Wong, Hendrick W. van Deventer, Debra J. Taxman, William Reed, Ping Li, Janice S. Blum, Karen P. McKinnon, and Jenny P.-Y. Ting
J Immunol 2006 177: 4271-4275. [Abstract] [Full Text] [PDF]  

Cutting Edge: Uniqueness of Lymphoid Chemokine Requirement for the Initiation and Maturation of Nasopharynx-Associated Lymphoid Tissue Organogenesis

Satoshi Fukuyama, Takahiro Nagatake, Dong-Young Kim, Kaoru Takamura, Eun Jeong Park, Tsuneyasu Kaisho, Norimitsu Tanaka, Yuichi Kurono, and Hiroshi Kiyono
J Immunol 2006 177: 4276-4280. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Preferential Involvement of Tim-3 in the Regulation of Hepatic CD8⁺ T Cells in Murine Acute Graft-versus-Host Disease

Tsunekazu Oikawa, Yosuke Kamimura, Hisaya Akiba, Hideo Yagita, Ko Okumura, Hiroki Takahashi, Mikio Zeniya, Hisao Tajiri, and Miyuki Azuma
J Immunol 2006 177: 4281-4287. [Abstract] [Full Text] [PDF]  

Combination of Vaccination and Chimeric Receptor Expressing T Cells Provides Improved Active Therapy of Tumors

Hui-Rong Jiang, David E. Gilham, Kate Mulryan, Natalia Kirillova, Robert E. Hawkins, and Peter L. Stern
J Immunol 2006 177: 4288-4298. [Abstract] [Full Text] [PDF]  

Dual Ligand Stimulation of RAW 264.7 Cells Uncovers Feedback Mechanisms That Regulate TLR-Mediated Gene Expression

Xiaocui Zhu, Mi Sook Chang, Robert C. Hsueh, Ron Taussig, Kelly D. Smith, Melvin I. Simon, and Sangdun Choi
J Immunol 2006 177: 4299-4310. [Abstract] [Full Text] [PDF] Data Supplement  

T Cell, Ig Domain, Mucin Domain-2 Gene-Deficient Mice Reveal a Novel Mechanism for the Regulation of Th2 Immune Responses and Airway Inflammation

Paul D. Rennert, Takaharu Ichimura, Irene D. Sizing, Veronique Bailly, Zhifang Li, Rachel Rennard, Patricia McCoon, Lourdes Pablo, Steven Miklasz, Leticia Tarilonte, and Joseph V. Bonventre
J Immunol 2006 177: 4311-4321. [Abstract] [Full Text] [PDF]  

Transient Receptor Potential Vanilloid Subtype 1 Mediates Microglial Cell Death In Vivo and In Vitro via Ca²⁺-Mediated Mitochondrial Damage and Cytochrome c Release

Sang R. Kim, Seung U. Kim, Uhtaek Oh, and Byung K. Jin
J Immunol 2006 177: 4322-4329. [Abstract] [Full Text] [PDF]  

Three Memory Subsets of Human CD8⁺ T Cells Differently Expressing Three Cytolytic Effector Molecules

Hiroshi Takata and Masafumi Takiguchi
J Immunol 2006 177: 4330-4340. [Abstract] [Full Text] [PDF]  

The Human CD77^– B Cell Population Represents a Heterogeneous Subset of Cells Comprising Centroblasts, Centrocytes, and Plasmablasts, Prompting Phenotypical Revision

Carl-Magnus Högerkorp and Carl A. K. Borrebaeck
J Immunol 2006 177: 4341-4349. [Abstract] [Full Text] [PDF]  

Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema Are Attenuated in CCR6-Deficient Mice

Ken R. Bracke, An I. D’hulst, Tania Maes, Katrien B. Moerloose, Ingel K. Demedts, Serge Lebecque, Guy F. Joos, and Guy G. Brusselle
J Immunol 2006 177: 4350-4359. [Abstract] [Full Text] [PDF]  

Identification and Characterization of the Precursors Committed to Osteoclasts Induced by TNF-Related Activation-Induced Cytokine/Receptor Activator of NF-B Ligand

Ayako Mochizuki, Masamichi Takami, Tadaharu Kawawa, Reina Suzumoto, Takahisa Sasaki, Akihiko Shiba, Hiroaki Tsukasaki, Baohong Zhao, Rika Yasuhara, Tetsuo Suzawa, Yoichi Miyamoto, Yongwon Choi, and Ryutaro Kamijo
J Immunol 2006 177: 4360-4368. [Abstract] [Full Text] [PDF]  

Inhibitory Role of IFN--Inducible Lysosomal Thiol Reductase in T Cell Activation

Igor Barjaktarevic, Ayman Rahman, Sasa Radoja, Branka Bogunovic, Alison Vollmer, Stanislav Vukmanovic, and Maja Maric
J Immunol 2006 177: 4369-4375. [Abstract] [Full Text] [PDF]  

Blockade of CTLA-4 on CD4⁺CD25⁺ Regulatory T Cells Abrogates Their Function In Vivo

Simon Read, Rebecca Greenwald, Ana Izcue, Nicholas Robinson, Didier Mandelbrot, Loise Francisco, Arlene H. Sharpe, and Fiona Powrie
J Immunol 2006 177: 4376-4383. [Abstract] [Full Text] [PDF]  

Induction of Autoimmunity by Expansion of Autoreactive CD4⁺CD62L^low Cells In Vivo

Bastian Amend, Hong Doster, Christian Lange, Evelyn Dubois, Hubert Kalbacher, Arthur Melms, and Felix Bischof
J Immunol 2006 177: 4384-4390. [Abstract] [Full Text] [PDF]  

The Effects of Age, Thymectomy, and HIV Infection on and TCR Excision Circles in Naive T Cells

Carline van den Dool and Rob J. de Boer
J Immunol 2006 177: 4391-4401. [Abstract] [Full Text] [PDF]  

A Large T Cell Invagination with CD2 Enrichment Resets Receptor Engagement in the Immunological Synapse

Kentner Singleton, Nadia Parvaze, Kavyya R. Dama, Kenneth S. Chen, Paula Jennings, Bozidar Purtic, Michael D. Sjaastad, Christopher Gilpin, Mark M. Davis, and Christoph Wülfing
J Immunol 2006 177: 4402-4413. [Abstract] [Full Text] [PDF] Data Supplement  

Host-Derived Langerhans Cells Persist after MHC-Matched Allografting Independent of Donor T Cells and Critically Influence the Alloresponses Mediated by Donor Lymphocyte Infusions

Nadira Durakovic, Karl B. Bezak, Mario Skarica, Vedran Radojcic, Ephraim J. Fuchs, George F. Murphy, and Leo Luznik
J Immunol 2006 177: 4414-4425. [Abstract] [Full Text] [PDF]  

Early Exposure to IL-4 Stabilizes IL-4 mRNA in CD4⁺ T Cells via RNA-Binding Protein HuR

Timur O. Yarovinsky, Noah S. Butler, Martha M. Monick, and Gary W. Hunninghake
J Immunol 2006 177: 4426-4435. [Abstract] [Full Text] [PDF]  

Regulatory Role of T Cells in the Recruitment of CD4⁺ and CD8⁺ T Cells to Lung and Subsequent Pulmonary Fibrosis

Philip L. Simonian, Christina L. Roark, Fernando Diaz del Valle, Brent E. Palmer, Ivor S. Douglas, Koichi Ikuta, Willi K. Born, Rebecca L. O’Brien, and Andrew P. Fontenot
J Immunol 2006 177: 4436-4443. [Abstract] [Full Text] [PDF]  

Induction of C3 and CCL2 by C3a in Keratinocytes: A Novel Autocrine Amplification Loop of Inflammatory Skin Reactions

Rahul Purwar, Miriam Wittmann, Jörg Zwirner, Martin Oppermann, Michael Kracht, Oliver Dittrich-Breiholz, Ralf Gutzmer, and Thomas Werfel
J Immunol 2006 177: 4444-4450. [Abstract] [Full Text] [PDF]  

Cell-Autonomous CCL5 Transcription by Memory CD8 T Cells Is Regulated by IL-4

Antoine Marçais, Charles-Antoine Coupet, Thierry Walzer, Martine Tomkowiak, Raffaella Ghittoni, and Jacqueline Marvel
J Immunol 2006 177: 4451-4457. [Abstract] [Full Text] [PDF]  

Augmented IL-7 Signaling during Viral Infection Drives Greater Expansion of Effector T Cells but Does Not Enhance Memory

Joseph C. Sun, Sophie M. Lehar, and Michael J. Bevan
J Immunol 2006 177: 4458-4463. [Abstract] [Full Text] [PDF]  

Functional Dichotomy between OX40 and 4-1BB in Modulating Effector CD8 T Cell Responses

Seung-Woo Lee, Yunji Park, Aihua Song, Hilde Cheroutre, Byoung S. Kwon, and Michael Croft
J Immunol 2006 177: 4464-4472. [Abstract] [Full Text] [PDF]  

CpG DNA Activates Survival in Murine Macrophages through TLR9 and the Phosphatidylinositol 3-Kinase-Akt Pathway

David P. Sester, Kristian Brion, Angela Trieu, Helen S. Goodridge, Tara L. Roberts, Jasmyn Dunn, David A. Hume, Katryn J. Stacey, and Matthew J. Sweet
J Immunol 2006 177: 4473-4480. [Abstract] [Full Text] [PDF]  

B Cells Drive Early T Cell Autoimmunity In Vivo prior to Dendritic Cell-Mediated Autoantigen Presentation

Jun Yan, Bohdan P. Harvey, Renelle J. Gee, Mark J. Shlomchik, and Mark J. Mamula
J Immunol 2006 177: 4481-4487. [Abstract] [Full Text] [PDF]  

The Majority of Human Peripheral Blood CD4⁺CD25^highFoxp3⁺ Regulatory T Cells Bear Functional Skin-Homing Receptors

Kazuki Hirahara, Luzheng Liu, Rachael A. Clark, Kei-ichi Yamanaka, Robert C. Fuhlbrigge, and Thomas S. Kupper
J Immunol 2006 177: 4488-4494. [Abstract] [Full Text] [PDF]  

Ligation of CD80 Is Critical for High-Level CD25 Expression on CD8⁺ T Lymphocytes

Sharmila Pejawar-Gaddy and Martha A. Alexander-Miller
J Immunol 2006 177: 4495-4502. [Abstract] [Full Text] [PDF]  

A Novel Role for Viral-Defective Interfering Particles in Enhancing Dendritic Cell Maturation

Jacob S. Yount, Thomas A. Kraus, Curt M. Horvath, Thomas M. Moran, and Carolina B. López
J Immunol 2006 177: 4503-4513. [Abstract] [Full Text] [PDF]  

Trauma-Hemorrhage Induces Depressed Splenic Dendritic Cell Functions in Mice

Takashi Kawasaki, William J. Hubbard, Mashkoor A. Choudhry, Martin G. Schwacha, Kirby I. Bland, and Irshad H. Chaudry
J Immunol 2006 177: 4514-4520. [Abstract] [Full Text] [PDF]  

Homeostatic Proliferation as an Isolated Variable Reverses CD8⁺ T Cell Anergy and Promotes Tumor Rejection

Ian E. Brown, Christian Blank, Justin Kline, Aalok K. Kacha, and Thomas F. Gajewski
J Immunol 2006 177: 4521-4529. [Abstract] [Full Text] [PDF]  

STAT1-Independent Cell Type-Specific Regulation of Antiviral APOBEC3G by IFN-

Phuong Thi Nguyen Sarkis, Songcheng Ying, Rongzhen Xu, and Xiao-Fang Yu
J Immunol 2006 177: 4530-4540. [Abstract] [Full Text] [PDF]  

Intracellular Protein Modification Associated with Altered T Cell Functions in Autoimmunity

Mei-Ling Yang, Hester A. Doyle, Renelle J. Gee, Jonathan D. Lowenson, Steven Clarke, Brian R. Lawson, Dana W. Aswad, and Mark J. Mamula
J Immunol 2006 177: 4541-4549. [Abstract] [Full Text] [PDF]  

Rac1 Negatively Regulates Lipopolysaccharide-Induced IL-23 p19 Expression in Human Macrophages and Dendritic Cells and NF-B p65 trans Activation Plays a Novel Role

Mitsuyoshi Utsugi, Kunio Dobashi, Tamotsu Ishizuka, Tadayoshi Kawata, Takeshi Hisada, Yasuo Shimizu, Akihiro Ono, and Masatomo Mori
J Immunol 2006 177: 4550-4557. [Abstract] [Full Text] [PDF]  

CD25⁺CD4⁺ Regulatory T Cells and Memory T Cells Prevent Lymphopenia-Induced Proliferation of Naive T Cells in Transient States of Lymphopenia

Christine Bourgeois and Brigitta Stockinger
J Immunol 2006 177: 4558-4566. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

PKB Rescues Calcineurin/NFAT-Induced Arrest of Rag Expression and Pre-T Cell Differentiation

Amiya K. Patra, Thomas Drewes, Swen Engelmann, Sergei Chuvpilo, Hiroyuki Kishi, Thomas Hünig, Edgar Serfling, and Ursula H. Bommhardt
J Immunol 2006 177: 4567-4576. [Abstract] [Full Text] [PDF]  

Structural Characterization of Mycobacterial Phosphatidylinositol Mannoside Binding to Mouse CD1d

Dirk M. Zajonc, Gary D. Ainge, Gavin F. Painter, Wayne B. Severn, and Ian A. Wilson
J Immunol 2006 177: 4577-4583. [Abstract] [Full Text] [PDF]  

Repression of IFN- Induction of Class II Transactivator: A Role for PRDM1/Blimp-1 in Regulation of Cytokine Signaling

Reuben M. Tooze, Sophie Stephenson, and Gina M. Doody
J Immunol 2006 177: 4584-4593. [Abstract] [Full Text] [PDF]  

Characterization of a Novel C-Type Lectin, Bombyx mori Multibinding Protein, from the B. mori Hemolymph: Mechanism of Wide-Range Microorganism Recognition and Role in Immunity

Ayako Watanabe, Sousui Miyazawa, Madoka Kitami, Hiroko Tabunoki, Kenjiro Ueda, and Ryoichi Sato
J Immunol 2006 177: 4594-4604. [Abstract] [Full Text] [PDF]  

Molecular Mechanisms for Transcriptional Regulation of Human High-Affinity IgE Receptor -Chain Gene Induced by GM-CSF

Kyoko Takahashi, Natsuko Hayashi, Shuichi Kaminogawa, and Chisei Ra
J Immunol 2006 177: 4605-4611. [Abstract] [Full Text] [PDF]  

IMMUNOGENETICS:

Identification of Susceptibility Loci for Skin Disease in a Murine Psoriasis Model

Daniel Kess, Anna-Karin B. Lindqvist, Thorsten Peters, Honglin Wang, Jan Zamek, Roswitha Nischt, Karl W. Broman, Robert Blakytny, Thomas Krieg, Rikard Holmdahl, and Karin Scharffetter-Kochanek
J Immunol 2006 177: 4612-4619. [Abstract] [Full Text] [PDF]  

MHC Class II Molecules Control Murine B Cell Responsiveness to Lipopolysaccharide Stimulation

Joana Rodo, Lígia A. Gonçalves, Jocelyne Demengeot, António Coutinho, and Carlos Penha-Gonçalves
J Immunol 2006 177: 4620-4626. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Restoration of Natural IgM Production from Liver B Cells by Exogenous IL-18 Improves the Survival of Burn-Injured Mice Infected with Pseudomonas aeruginosa

Manabu Kinoshita, Nariyoshi Shinomiya, Satoshi Ono, Hironori Tsujimoto, Toshinobu Kawabata, Atsushi Matsumoto, Hoshio Hiraide, and Shuhji Seki
J Immunol 2006 177: 4627-4635. [Abstract] [Full Text] [PDF]  

Inhibition of IL-2 Induced IL-10 Production as a Principle of Phase-Specific Immunotherapy

Manish Bodas, Nitya Jain, Amit Awasthi, Sunil Martin, Raghu Kumar Penke Loka, Dineshkumar Dandekar, Debashis Mitra, and Bhaskar Saha
J Immunol 2006 177: 4636-4643. [Abstract] [Full Text] [PDF]  

Fatal Recall Responses Mediated by CD8 T cells during Intracellular Bacterial Challenge Infection

Constantine Bitsaktsis and Gary Winslow
J Immunol 2006 177: 4644-4651. [Abstract] [Full Text] [PDF]  

Immunologic Homeostasis during Infection: Coexistence of Strong Pulmonary Cell-Mediated Immunity to Secondary Cryptococcus neoformans Infection While the Primary Infection Still Persists at Low Levels in the Lungs

Dennis M. Lindell, Megan N. Ballinger, Roderick A. McDonald, Galen B. Toews, and Gary B. Huffnagle
J Immunol 2006 177: 4652-4661. [Abstract] [Full Text] [PDF]  

IL-17 Production Is Dominated by T Cells rather than CD4 T Cells during Mycobacterium tuberculosis Infection

Euan Lockhart, Angela M. Green, and JoAnne L. Flynn
J Immunol 2006 177: 4662-4669. [Abstract] [Full Text] [PDF]  

Murine -Herpesvirus 68 Limits Naturally Occurring CD4⁺CD25⁺ T Regulatory Cell Activity following Infection

Nancy Gasper-Smith, Ian Marriott, and Kenneth L. Bost
J Immunol 2006 177: 4670-4678. [Abstract] [Full Text] [PDF]  

Specific Recognition of Candida albicans by Macrophages Requires Galectin-3 to Discriminate Saccharomyces cerevisiae and Needs Association with TLR2 for Signaling

Thierry Jouault, Miryam El Abed-El Behi, María Martínez-Esparza, Laetitia Breuilh, Pierre-André Trinel, Mathias Chamaillard, Francois Trottein, and Daniel Poulain
J Immunol 2006 177: 4679-4687. [Abstract] [Full Text] [PDF]  

The Reduced Bactericidal Function of Complement C5-Deficient Murine Macrophages Is Associated with Defects in the Synthesis and Delivery of Reactive Oxygen Radicals to Mycobacterial Phagosomes

D. Sundarsingh Daniel, Guixiang Dai, Christopher R. Singh, Devin R. Lindsey, Amanda K. Smith, Subramanian Dhandayuthapani, Robert L. Hunter, Jr, and Chinnaswamy Jagannath
J Immunol 2006 177: 4688-4698. [Abstract] [Full Text] [PDF]  

Differential Selection Pressure Exerted on HIV by CTL Targeting Identical Epitopes but Restricted by Distinct HLA Alleles from the Same HLA Supertype

Alasdair Leslie, David A. Price, Pamela Mkhize, Karen Bishop, Almas Rathod, Cheryl Day, Hayley Crawford, Isobella Honeyborne, Tedi E. Asher, Graz Luzzi, Anne Edwards, Christine M. Rosseau, James I. Mullins, Gareth Tudor-Williams, Vas Novelli, Christian Brander, Daniel C. Douek, Photini Kiepiela, Bruce D. Walker, and Philip J. R. Goulder
J Immunol 2006 177: 4699-4708. [Abstract] [Full Text] [PDF]  

High Vaccine Efficacy against Shigellosis of Recombinant Noninvasive Shigella Mutant That Expresses Yersinia Invasin

Toshihiko Suzuki, Yuko Yoshikawa, Hiroshi Ashida, Hiroki Iwai, Takahito Toyotome, Hidenori Matsui, and Chihiro Sasakawa
J Immunol 2006 177: 4709-4717. [Abstract] [Full Text] [PDF]  

Galectin-3 Induces Death of Candida Species Expressing Specific -1,2-Linked Mannans

Luciana Kohatsu, Daniel K. Hsu, Armin G. Jegalian, Fu-Tong Liu, and Linda G. Baum
J Immunol 2006 177: 4718-4726. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Activation of the Lectin Pathway by Natural IgM in a Model of Ischemia/Reperfusion Injury

Ming Zhang, Kazue Takahashi, Elisabeth M. Alicot, Thomas Vorup-Jensen, Benedikt Kessler, Steffen Thiel, Jens Christian Jensenius, R. Alan B. Ezekowitz, Francis D. Moore, and Michael C. Carroll
J Immunol 2006 177: 4727-4734. [Abstract] [Full Text] [PDF]  

TLR3 Ligation Activates an Antiviral Response in Human Fetal Astrocytes: A Role for Viperin/cig5

Mark A. Rivieccio, Hyeon-Sook Suh, Yongmei Zhao, Meng-Liang Zhao, Keh Chuang Chin, Sunhee C. Lee, and Celia F. Brosnan
J Immunol 2006 177: 4735-4741. [Abstract] [Full Text] [PDF]  

The Monoclonal Antibody CHO-131 Identifies a Subset of Cutaneous Lymphocyte-Associated Antigen T Cells Enriched in P-Selectin-Binding Cells

Zhenya Ni, James J. Campbell, Gloria Niehans, and Bruce Walcheck
J Immunol 2006 177: 4742-4748. [Abstract] [Full Text] [PDF]  

Basal Rather Than Induced Heme Oxygenase-1 Levels Are Crucial in the Antioxidant Cytoprotection

Sei-ichiro Tsuchihashi, Masha Livhits, Yuan Zhai, Ronald W. Busuttil, Jesus A. Araujo, and Jerzy W. Kupiec-Weglinski
J Immunol 2006 177: 4749-4757. [Abstract] [Full Text] [PDF]  

Follistatin-Like Protein-1 Is a Novel Proinflammatory Molecule

Takako Miyamae, Anthony D. Marinov, Dawn Sowders, David C. Wilson, Jason Devlin, Robert Boudreau, Paul Robbins, and Raphael Hirsch
J Immunol 2006 177: 4758-4762. [Abstract] [Full Text] [PDF]  

TCR Down-Regulation under Chronic Inflammation Is Mediated by Myeloid Suppressor Cells Differentially Distributed between Various Lymphatic Organs

Analía V. Ezernitchi, Ilan Vaknin, Leonor Cohen-Daniel, Ofer Levy, Efrat Manaster, Amal Halabi, Eli Pikarsky, Lior Shapira, and Michal Baniyash
J Immunol 2006 177: 4763-4772. [Abstract] [Full Text] [PDF]  

Renal Collecting Duct Epithelial Cells React to Pyelonephritis-Associated Escherichia coli by Activating Distinct TLR4-Dependent and -Independent Inflammatory Pathways

Cécilia Chassin, Jean-Michel Goujon, Sylvie Darche, Laurence du Merle, Marcelle Bens, Françoise Cluzeaud, Catherine Werts, Eric Ogier-Denis, Chantal Le Bouguénec, Dominique Buzoni-Gatel, and Alain Vandewalle
J Immunol 2006 177: 4773-4784. [Abstract] [Full Text] [PDF]  

Cyclooxygenase-1 Overexpression Decreases Basal Airway Responsiveness but Not Allergic Inflammation

Jeffrey W. Card, Michelle A. Carey, J. Alyce Bradbury, Joan P. Graves, Fred B. Lih, Michael P. Moorman, Daniel L. Morgan, Laura M. DeGraff, Yun Zhao, Julie F. Foley, and Darryl C. Zeldin
J Immunol 2006 177: 4785-4793. [Abstract] [Full Text] [PDF]  

A Novel C5a Receptor-Tissue Factor Cross-Talk in Neutrophils Links Innate Immunity to Coagulation Pathways

Konstantinos Ritis, Michael Doumas, Dimitrios Mastellos, Anastasia Micheli, Stavros Giaglis, Paola Magotti, Stavros Rafail, Georgios Kartalis, Paschalis Sideras, and John D. Lambris
J Immunol 2006 177: 4794-4802. [Abstract] [Full Text] [PDF]  

Complement-Dependent Control of Teratoma Formation by Embryonic Stem Cells

Cody A. Koch, Corinne E. Jordan, and Jeffrey L. Platt
J Immunol 2006 177: 4803-4809. [Abstract] [Full Text] [PDF]  

A Role for Inflammatory Mediators in the Induction of Immunoregulatory B Cells

Yumi Matsumura, Scott N. Byrne, Dat X. Nghiem, Yasuko Miyahara, and Stephen E. Ullrich
J Immunol 2006 177: 4810-4817. [Abstract] [Full Text] [PDF]  

Regulation of IL-1 and TNF Receptor Expression and Function by Endogenous Macrophage Migration Inhibitory Factor

Myew-Ling Toh, Daniel Aeberli, Derek Lacey, Yuan Yang, Leilani L. Santos, Michael Clarkson, Laveena Sharma, Colin Clyne, and Eric F. Morand
J Immunol 2006 177: 4818-4825. [Abstract] [Full Text] [PDF]  

A Microbial TLR2 Agonist Imparts Macrophage-Activating Ability to Apolipoprotein A-1

Akira Hasebe, Nathan D. Pennock, Hong-Hua Mu, Fok V. Chan, Michael L. Taylor, and Barry C. Cole
J Immunol 2006 177: 4826-4832. [Abstract] [Full Text] [PDF]  

Exposure of the Promonocytic Cell Line THP-1 to Escherichia coli Induces IFN--Inducible Lysosomal Thiol Reductase Expression by Inflammatory Cytokines

Rebecca L. Lackman and Peter Cresswell
J Immunol 2006 177: 4833-4840. [Abstract] [Full Text] [PDF]  

Collaborative Action of NF-B and p38 MAPK Is Involved in CpG DNA-Induced IFN- and Chemokine Production in Human Plasmacytoid Dendritic Cells

Youko Osawa, Sumiko Iho, Rumiko Takauji, Hisakazu Takatsuka, Saburo Yamamoto, Takayuki Takahashi, Satomi Horiguchi, Yoshimasa Urasaki, Takasumi Matsuki, and Shigeharu Fujieda
J Immunol 2006 177: 4841-4852. [Abstract] [Full Text] [PDF]  

Caveolin-1 Regulates NF-B Activation and Lung Inflammatory Response to Sepsis Induced by Lipopolysaccharide

Sean Garrean, Xiao-Pei Gao, Victor Brovkovych, Jun Shimizu, You-Yang Zhao, Stephen M. Vogel, and Asrar B. Malik
J Immunol 2006 177: 4853-4860. [Abstract] [Full Text] [PDF]  

Eosinophil-Derived Cationic Proteins Activate the Synthesis of Remodeling Factors by Airway Epithelial Cells

Sophie Pégorier, Lori A. Wagner, Gerald J. Gleich, and Marina Pretolani
J Immunol 2006 177: 4861-4869. [Abstract] [Full Text] [PDF]  

Novel Approach to Inhibit Asthma-Mediated Lung Inflammation Using Anti-CD147 Intervention

William M. Gwinn, Jesse M. Damsker, Rustom Falahati, Ifeanyi Okwumabua, Ann Kelly-Welch, Achsah D. Keegan, Christophe Vanpouille, James J. Lee, Lindsay A. Dent, David Leitenberg, Michael I. Bukrinsky, and Stephanie L. Constant
J Immunol 2006 177: 4870-4879. [Abstract] [Full Text] [PDF]  

Native High-Density Lipoprotein Augments Monocyte Responses to Lipopolysaccharide (LPS) by Suppressing the Inhibitory Activity of LPS-Binding Protein

Patricia A. Thompson and Richard L. Kitchens
J Immunol 2006 177: 4880-4887. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Essential Role for IL-10 in Resistance to Lipopolysaccharide-Induced Preterm Labor in Mice

Sarah A. Robertson, Rebecca J. Skinner, and Alison S. Care
J Immunol 2006 177: 4888-4896. [Abstract] [Full Text] [PDF]  

Functional Reversion of Antigen-Specific CD8⁺ T Cells from Patients with Hodgkin Lymphoma following In Vitro Stimulation with Recombinant Polyepitope

Corey Smith, Leanne Cooper, Melinda Burgess, Michael Rist, Natasha Webb, Eleanore Lambley, Judy Tellam, Paula Marlton, John F. Seymour, Maher Gandhi, and Rajiv Khanna
J Immunol 2006 177: 4897-4906. [Abstract] [Full Text] [PDF]  

An Unconventional Antigen Translated by a Novel Internal Ribosome Entry Site Elicits Antitumor Humoral Immune Reactions

Zeyu Xiong, Enli Liu, Yan Yan, Richard T. Silver, Fan Yang, Irene H. Chen, Yangyang Chen, Srdan Verstovsek, Hong Wang, Josef Prchal, and Xiao-Feng Yang
J Immunol 2006 177: 4907-4916. [Abstract] [Full Text] [PDF]  

An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis

Eiko Toichi, Gisela Torres, Thomas S. McCormick, Timothy Chang, Mary Ann Mascelli, Catharine L. Kauffman, Nancy Aria, Alice B. Gottlieb, Daniel E. Everitt, Bart Frederick, Charles E. Pendley, and Kevin D. Cooper
J Immunol 2006 177: 4917-4926. [Abstract] [Full Text] [PDF]  

ICOS Deficiency Is Associated with a Severe Reduction of CXCR5⁺CD4 Germinal Center Th Cells

Lukas Bossaller, Jan Burger, Ruth Draeger, Bodo Grimbacher, Rolf Knoth, Alessandro Plebani, Anne Durandy, Ulrich Baumann, Michael Schlesier, Andrew A. Welcher, Hans Hartmut Peter, and Klaus Warnatz
J Immunol 2006 177: 4927-4932. [Abstract] [Full Text] [PDF]  

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