IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2006 176: 1293-1294. [Full Text] [PDF]  

PILLARS OF IMMUNOLOGY:

In the Beginning Was Sm

George C. Tsokos
J Immunol 2006 176: 1295-1296. [Full Text] [PDF] [Original Pillars Article]  

Pillars Article: Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus. J. Immunol. 1966. 96: 464–471.

E. M. Tan and H. G. Kunkel
J Immunol 2006 176: 1297-1304. [PDF]  

BRIEF REVIEWS:

The Central Role of the Alternative Complement Pathway in Human Disease

Joshua M. Thurman and V. Michael Holers
J Immunol 2006 176: 1305-1310. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Identification of E-Cadherin as a Ligand for the Murine Killer Cell Lectin-Like Receptor G1

Carsten Gründemann, Monika Bauer, Oliver Schweier, Nanette von Oppen, Ute Lässing, Philippe Saudan, Karl-Friedrich Becker, Klaus Karp, Thomas Hanke, Martin F. Bachmann, and Hanspeter Pircher
J Immunol 2006 176: 1311-1315. [Abstract] [Full Text] [PDF]  

Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF- Sensitivity In Vitro and In Vivo

Elizabeth A. Wohlfert, Leonid Gorelik, Robert Mittler, Richard A. Flavell, and Robert B. Clark
J Immunol 2006 176: 1316-1320. [Abstract] [Full Text] [PDF]  

Cutting Edge: A Novel Nonoxidative Phagosomal Mechanism Exerted by Cathepsin-D Controls Listeria monocytogenes Intracellular Growth

Elida del Cerro-Vadillo, Fidel Madrazo-Toca, Eugenio Carrasco-Marín, Lorena Fernandez-Prieto, Christian Beck, Francisco Leyva-Cobián, Paul Saftig, and Carmen Alvarez-Dominguez
J Immunol 2006 176: 1321-1325. [Abstract] [Full Text] [PDF]  

Cutting Edge: Prostaglandin D₂ Enhances Leukotriene C₄ Synthesis by Eosinophils during Allergic Inflammation: Synergistic In Vivo Role of Endogenous Eotaxin

Fabio P. Mesquita-Santos, Adriana Vieira-de-Abreu, Andrea S. Calheiros, Isabela H. Figueiredo, Hugo C. Castro-Faria-Neto, Peter F. Weller, Patrícia T. Bozza, Bruno L. Diaz, and Christianne Bandeira-Melo
J Immunol 2006 176: 1326-1330. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Soluble HLA-G Inhibits Cell Cycle Progression in Human Alloreactive T Lymphocytes

Rajia Bahri, Francois Hirsch, Adeline Josse, Nathalie Rouas-Freiss, Nicolas Bidere, Aime Vasquez, Edgardo D. Carosella, Bernard Charpentier, and Antoine Durrbach
J Immunol 2006 176: 1331-1339. [Abstract] [Full Text] [PDF]  

The Endoplasmic Reticulum Is a Key Component of the Plasma Cell Death Pathway

Nadège Pelletier, Montserrat Casamayor-Pallejà, Karelle De Luca, Paul Mondière, Frédéric Saltel, Pierre Jurdic, Chantal Bella, Laurent Genestier, and Thierry Defrance
J Immunol 2006 176: 1340-1347. [Abstract] [Full Text] [PDF]  

Direct Costimulatory Effect of TLR3 Ligand Poly(I:C) on Human T Lymphocytes

Daniela Wesch, Susann Beetz, Hans-Heinrich Oberg, Matthias Marget, Kirsten Krengel, and Dieter Kabelitz
J Immunol 2006 176: 1348-1354. [Abstract] [Full Text] [PDF]  

Flightless I Homolog Negatively Modulates the TLR Pathway

Tianyi Wang, Tsung-Hsien Chuang, Tapani Ronni, Sheng Gu, Yu-Chun Du, Hong Cai, Hui-Qiao Sun, Helen L. Yin, and Xian Chen
J Immunol 2006 176: 1355-1362. [Abstract] [Full Text] [PDF]  

Immunologic Control of Tumors by In Vivo Fc Receptor-Targeted Antigen Loading in Conjunction with Double-Stranded RNA-Mediated Immune Modulation

Adrian Bot, Dan Smith, Bill Phillips, Simona Bot, Constantin Bona, and Habib Zaghouani
J Immunol 2006 176: 1363-1374. [Abstract] [Full Text] [PDF]  

Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function

Cunren Liu, Shaohua Yu, Kurt Zinn, Jianhua Wang, Liming Zhang, Yujiang Jia, John C. Kappes, Stephen Barnes, Robert P. Kimberly, William E. Grizzle, and Huang-Ge Zhang
J Immunol 2006 176: 1375-1385. [Abstract] [Full Text] [PDF]  

Potentiation of Antigen-Stimulated V9V2 T Cell Cytokine Production by Immature Dendritic Cells (DC) and Reciprocal Effect on DC Maturation

Marie-Claire Devilder, Sophie Maillet, Isabelle Bouyge-Moreau, Emmanuel Donnadieu, Marc Bonneville, and Emmanuel Scotet
J Immunol 2006 176: 1386-1393. [Abstract] [Full Text] [PDF]  

Critical, but Conditional, Role of OX40 in Memory T Cell-Mediated Rejection

Minh Diem Vu, Michael R. Clarkson, Hideo Yagita, Laurence A. Turka, Mohamed H. Sayegh, and Xian Chang Li
J Immunol 2006 176: 1394-1401. [Abstract] [Full Text] [PDF]  

CD40 Expression by Microglial Cells Is Required for Their Completion of a Two-Step Activation Process during Central Nervous System Autoimmune Inflammation

Eugene D. Ponomarev, Leah P. Shriver, and Bonnie N. Dittel
J Immunol 2006 176: 1402-1410. [Abstract] [Full Text] [PDF]  

Soluble Form of T Cell Ig Mucin 3 Is an Inhibitory Molecule in T Cell-Mediated Immune Response

Hui Geng, Gui-Mei Zhang, Dong Li, Hui Zhang, Ye Yuan, Han-Gang Zhu, Han Xiao, Ling-Fei Han, and Zuo-Hua Feng
J Immunol 2006 176: 1411-1420. [Abstract] [Full Text] [PDF]  

A Cell-Type Specific CD1d Expression Program Modulates Invariant NKT Cell Development and Function

Michael I. Zimmer, Angela Colmone, Kyrie Felio, Honglin Xu, Averil Ma, and Chyung-Ru Wang
J Immunol 2006 176: 1421-1430. [Abstract] [Full Text] [PDF]  

Protein Expression of TNF- in Psoriatic Skin Is Regulated at a Posttranscriptional Level by MAPK-Activated Protein Kinase 2

Claus Johansen, Anne Toftegaard Funding, Kristian Otkjaer, Knud Kragballe, Uffe Birk Jensen, Mogens Madsen, Lise Binderup, Tine Skak-Nielsen, Marianne Scheel Fjording, and Lars Iversen
J Immunol 2006 176: 1431-1438. [Abstract] [Full Text] [PDF]  

Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo

Tim Willinger, Tom Freeman, Mark Herbert, Hitoshi Hasegawa, Andrew J. McMichael, and Margaret F. C. Callan
J Immunol 2006 176: 1439-1446. [Abstract] [Full Text] [PDF]  

Tumor-Specific CD4⁺ T Cells Are Activated by "Cross-Dressed" Dendritic Cells Presenting Peptide-MHC Class II Complexes Acquired from Cell-Based Cancer Vaccines

Brian P. Dolan, Kenneth D. Gibbs, Jr., and Suzanne Ostrand-Rosenberg
J Immunol 2006 176: 1447-1455. [Abstract] [Full Text] [PDF]  

CXCR3/CXCR3 Ligand Biological Axis Impairs RENCA Tumor Growth by a Mechanism of Immunoangiostasis

Judong Pan, Marie D. Burdick, John A. Belperio, Ying Ying Xue, Craig Gerard, Sherven Sharma, Steven M. Dubinett, and Robert M. Strieter
J Immunol 2006 176: 1456-1464. [Abstract] [Full Text] [PDF]  

Protein Vaccines Induce Uncommitted IL-2-Secreting Human and Mouse CD4 T Cells, Whereas Infections Induce More IFN--Secreting Cells

Anagha A. Divekar, Dietmar M. W. Zaiss, F. Eun-Hyung Lee, Dacheng Liu, David J. Topham, Alice J. A. M. Sijts, and Tim R. Mosmann
J Immunol 2006 176: 1465-1473. [Abstract] [Full Text] [PDF]  

Enhanced FTY720-Mediated Lymphocyte Homing Requires Gi Signaling and Depends on ₂ and ₇ Integrin

Oliver Pabst, Heike Herbrand, Stefanie Willenzon, Tim Worbs, Angela Schippers, Werner Müller, Günter Bernhardt, and Reinhold Förster
J Immunol 2006 176: 1474-1480. [Abstract] [Full Text] [PDF]  

Splenic Dendritic Cells Induced by Oral Antigen Administration Are Important for the Transfer of Oral Tolerance in an Experimental Model of Asthma

Katsuya Nagatani, Makoto Dohi, Yasuo To, Ryoichi Tanaka, Katsuhide Okunishi, Kazuyuki Nakagome, Kayo Sagawa, Yudo Tanno, Yoshinori Komagata, and Kazuhiko Yamamoto
J Immunol 2006 176: 1481-1489. [Abstract] [Full Text] [PDF]  

IL-21 Down-Regulates NKG2D/DAP10 Expression on Human NK and CD8⁺ T Cells

Steven J. Burgess, Alina I. Marusina, Ishani Pathmanathan, Francisco Borrego, and John E. Coligan
J Immunol 2006 176: 1490-1497. [Abstract] [Full Text] [PDF]  

CD8 T Cells, Like CD4 T Cells, Are Triggered by Multivalent Engagement of TCRs by MHC-Peptide Ligands but Not by Monovalent Engagement

Jennifer D. Stone and Lawrence J. Stern
J Immunol 2006 176: 1498-1505. [Abstract] [Full Text] [PDF]  

Expansion of Functionally Immature Transitional B Cells Is Associated with Human-Immunodeficient States Characterized by Impaired Humoral Immunity

Amanda K. Cuss, Danielle T. Avery, Jennifer L. Cannons, Li Jun Yu, Kim E. Nichols, Peter J. Shaw, and Stuart G. Tangye
J Immunol 2006 176: 1506-1516. [Abstract] [Full Text] [PDF]  

CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity

Yoshihiro Hayakawa and Mark J. Smyth
J Immunol 2006 176: 1517-1524. [Abstract] [Full Text] [PDF]  

Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules

Balik Dzhambazov, Kutty Selva Nandakumar, Jan Kihlberg, Lars Fugger, Rikard Holmdahl, and Mikael Vestberg
J Immunol 2006 176: 1525-1533. [Abstract] [Full Text] [PDF]  

Pregnancy-Associated Exosomes and Their Modulation of T Cell Signaling

Douglas D. Taylor, Sibel Akyol, and Cicek Gercel-Taylor
J Immunol 2006 176: 1534-1542. [Abstract] [Full Text] [PDF]  

Human and Thymocyte Development: TCR Gene Rearrangements, Intracellular TCR Expression, and Developmental Potential—Differences between Men and Mice

Michelle L. Joachims, Jennifer L. Chain, Scott W. Hooker, Christopher J. Knott-Craig, and Linda F. Thompson
J Immunol 2006 176: 1543-1552. [Abstract] [Full Text] [PDF]  

Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation

Natallia Mikhalkevich, Brian Becknell, Michael A. Caligiuri, Michael D. Bates, Richard Harvey, and Wei-ping Zheng
J Immunol 2006 176: 1553-1560. [Abstract] [Full Text] [PDF]  

TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts

Thomas B. Thornley, Michael A. Brehm, Thomas G. Markees, Leonard D. Shultz, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini, and Dale L. Greiner
J Immunol 2006 176: 1561-1570. [Abstract] [Full Text] [PDF]  

Tec Kinases Itk and Rlk Are Required for CD8⁺ T Cell Responses to Virus Infection Independent of Their Role in CD4⁺ T Cell Help

Luana O. Atherly, Michael A. Brehm, Raymond M. Welsh, and Leslie J. Berg
J Immunol 2006 176: 1571-1581. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer

Mark J. Smyth, Michele W. L. Teng, Jeremy Swann, Konstantinos Kyparissoudis, Dale I. Godfrey, and Yoshihiro Hayakawa
J Immunol 2006 176: 1582-1587. [Abstract] [Full Text] [PDF]  

Brain-Derived Heat Shock Protein 70-Peptide Complexes Induce NK Cell-Dependent Tolerance to Experimental Autoimmune Encephalomyelitis

Grazyna Galazka, Mariusz Stasiolek, Agata Walczak, Anna Jurewicz, Alicja Zylicz, Celia F. Brosnan, Cedric S. Raine, and Krzysztof W. Selmaj
J Immunol 2006 176: 1588-1599. [Abstract] [Full Text] [PDF]  

Respiratory Syncytial Virus G Protein and G Protein CX3C Motif Adversely Affect CX3CR1⁺ T Cell Responses

Jennifer Harcourt, Rene Alvarez, Les P. Jones, Christine Henderson, Larry J. Anderson, and Ralph A. Tripp
J Immunol 2006 176: 1600-1608. [Abstract] [Full Text] [PDF]  

CD4⁺CD25⁺ Regulatory T Cells Inhibit the Antigen-Dependent Expansion of Self-Reactive T Cells In Vivo

Tricia D. Zwar, Simon Read, Ian R. van Driel, and Paul A. Gleeson
J Immunol 2006 176: 1609-1617. [Abstract] [Full Text] [PDF]  

MR1-Restricted V19i Mucosal-Associated Invariant T Cells Are Innate T Cells in the Gut Lamina Propria That Provide a Rapid and Diverse Cytokine Response

Izumi Kawachi, Jorge Maldonado, Carey Strader, and Susan Gilfillan
J Immunol 2006 176: 1618-1627. [Abstract] [Full Text] [PDF]  

Cross-Positive Selection of Thymocytes Expressing a Single TCR by Multiple Major Histocompatibility Complex Molecules of Both Classes: Implications for CD4⁺ versus CD8⁺ Lineage Commitment

Koji Eshima, Harumi Suzuki, and Nobukata Shinohara
J Immunol 2006 176: 1628-1636. [Abstract] [Full Text] [PDF]  

Early Autoimmune Destruction of Islet Grafts Is Associated with a Restricted Repertoire of IGRP-Specific CD8⁺ T Cells in Diabetic Nonobese Diabetic Mice

Carmen P. Wong, Li Li, Jeffrey A. Frelinger, and Roland Tisch
J Immunol 2006 176: 1637-1644. [Abstract] [Full Text] [PDF]  

NKT Cells and IFN- Establish the Regulatory Environment for the Control of Diabetogenic T Cells in the Nonobese Diabetic Mouse

Judith A. Cain, Judith A. Smith, Jennifer K. Ondr, Bo Wang, and Jonathan D. Katz
J Immunol 2006 176: 1645-1654. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

The Nucleotide Targets of Somatic Mutation and the Role of Selection in Immunoglobulin Heavy Chains of a Teleost Fish

Feixue Yang, Geoffrey C. Waldbieser, and Craig J. Lobb
J Immunol 2006 176: 1655-1667. [Abstract] [Full Text] [PDF]  

Phosphatidylinositol 3-Kinase Functions as a Ras Effector in the Signaling Cascade That Regulates Dephosphorylation of the Actin-Remodeling Protein Cofilin after Costimulation of Untransformed Human T Lymphocytes

Guido H. Wabnitz, Gabriele Nebl, Martin Klemke, Andreas J. Schröder, and Yvonne Samstag
J Immunol 2006 176: 1668-1674. [Abstract] [Full Text] [PDF]  

Opioids Trigger ₅₁ Integrin-Mediated Monocyte Adhesion

Oscar M. Pello, Béatrice Duthey, David García-Bernal, José Miguel Rodríguez-Frade, Jens V. Stein, Joaquín Teixido, Carlos Martínez-A., and Mario Mellado
J Immunol 2006 176: 1675-1685. [Abstract] [Full Text] [PDF]  

Characterization of Functional Oligosaccharide Mimics of the Shigella flexneri Serotype 2a O-Antigen: Implications for the Development of a Chemically Defined Glycoconjugate Vaccine

Armelle Phalipon, Corina Costachel, Cyrille Grandjean, Audrey Thuizat, Catherine Guerreiro, Myriam Tanguy, Farida Nato, Brigitte Vulliez-Le Normand, Frédéric Bélot, Karen Wright, Véronique Marcel-Peyre, Philippe J. Sansonetti, and Laurence A. Mulard
J Immunol 2006 176: 1686-1694. [Abstract] [Full Text] [PDF]  

Glucocorticoids Engage Different Signal Transduction Pathways to Induce Apoptosis in Thymocytes and Mature T Cells

Dapeng Wang, Nora Müller, Kirsty G. McPherson, and Holger M. Reichardt
J Immunol 2006 176: 1695-1702. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Qa-1^b and CD94-NKG2a Interaction Regulate Cytolytic Activity of Herpes Simplex Virus-Specific Memory CD8⁺ T Cells in the Latently Infected Trigeminal Ganglia

Susmit Suvas, Ahmet Kursat Azkur, and Barry T. Rouse
J Immunol 2006 176: 1703-1711. [Abstract] [Full Text] [PDF]  

Immunity and Tolerance to Aspergillus Involve Functionally Distinct Regulatory T Cells and Tryptophan Catabolism

Claudia Montagnoli, Francesca Fallarino, Roberta Gaziano, Silvia Bozza, Silvia Bellocchio, Teresa Zelante, Wiswanath P. Kurup, Lucia Pitzurra, Paolo Puccetti, and Luigina Romani
J Immunol 2006 176: 1712-1723. [Abstract] [Full Text] [PDF]  

Experimental African Trypanosomiasis: A Subset of Pathogenic, IFN--Producing, MHC Class II-Restricted CD4⁺ T Cells Mediates Early Mortality in Highly Susceptible Mice

Meiqing Shi, Guojian Wei, Wanling Pan, and Henry Tabel
J Immunol 2006 176: 1724-1732. [Abstract] [Full Text] [PDF]  

Respiratory Syncytial Virus Induces TLR3 Protein and Protein Kinase R, Leading to Increased Double-Stranded RNA Responsiveness in Airway Epithelial Cells

Dayna J. Groskreutz, Martha M. Monick, Linda S. Powers, Timur O. Yarovinsky, Dwight C. Look, and Gary W. Hunninghake
J Immunol 2006 176: 1733-1740. [Abstract] [Full Text] [PDF]  

DC-SIGN Is a Receptor for Human Herpesvirus 8 on Dendritic Cells and Macrophages

Giovanna Rappocciolo, Frank J. Jenkins, Heather R. Hensler, Paolo Piazza, Mariel Jais, Luann Borowski, Simon C. Watkins, and Charles R. Rinaldo, Jr
J Immunol 2006 176: 1741-1749. [Abstract] [Full Text] [PDF]  

CD25⁺ Regulatory T Cell Depletion Augments Immunotherapy of Micrometastases by an IL-21-Secreting Cellular Vaccine

Alberto Comes, Ombretta Rosso, Anna Maria Orengo, Emma Di Carlo, Carlo Sorrentino, Raffaella Meazza, Tiziana Piazza, Barbara Valzasina, Patrizia Nanni, Mario P. Colombo, and Silvano Ferrini
J Immunol 2006 176: 1750-1758. [Abstract] [Full Text] [PDF]  

Immunological Characterization and Antibacterial Function of Persisting Granulocytes in Leukemic Patients Receiving Pulse Cytosine Arabinoside-Consolidation Chemotherapy on Days 1, 3, and 5

Maria-T. Krauth, Stefan Florian, Alexandra Böhm, Karoline Sonneck, Hermine Agis, Puchit Samorapoompichit, Alexander W. Hauswirth, Wolfgang R. Sperr, and Peter Valent
J Immunol 2006 176: 1759-1768. [Abstract] [Full Text] [PDF]  

Deficiency of Mannose-Binding Lectin Greatly Increases Susceptibility to Postburn Infection with Pseudomonas aeruginosa

Mette Møller-Kristensen, W. K. Eddie Ip, Lei Shi, Lakshmi D. Gowda, Michael R. Hamblin, Steffen Thiel, Jens Chr. Jensenius, R. Alan B. Ezekowitz, and Kazue Takahashi
J Immunol 2006 176: 1769-1775. [Abstract] [Full Text] [PDF]  

Bacillus anthracis Edema Toxin Acts as an Adjuvant for Mucosal Immune Responses to Nasally Administered Vaccine Antigens

Alexandra Duverger, Raymond J. Jackson, Frederick W. van Ginkel, Romy Fischer, Angela Tafaro, Stephen H. Leppla, Kohtaro Fujihashi, Hiroshi Kiyono, Jerry R. McGhee, and Prosper N. Boyaka
J Immunol 2006 176: 1776-1783. [Abstract] [Full Text] [PDF]  

Induction of Positive Cellular and Humoral Immune Responses by a Prime-Boost Vaccine Encoded with Simian Immunodeficiency Virus gag/pol

Kenji Someya, Yasushi Ami, Tadashi Nakasone, Yasuyuki Izumi, Kazuhiro Matsuo, Shigeo Horibata, Ke-Qin Xin, Hiroshi Yamamoto, Kenji Okuda, Naoki Yamamoto, and Mitsuo Honda
J Immunol 2006 176: 1784-1795. [Abstract] [Full Text] [PDF]  

Identification of Cross-Reactive Peptides Using Combinatorial Libraries Circumvents Tolerance against Her-2/neu-Immunodominant Epitope

Joseph Lustgarten, Ana L. Dominguez, and Clemencia Pinilla
J Immunol 2006 176: 1796-1805. [Abstract] [Full Text] [PDF]  

Human Macrophages Do Not Require Phagosome Acidification to Mediate Fungistatic/Fungicidal Activity against Histoplasma capsulatum

Simon L. Newman, Lisa Gootee, Jeremy Hilty, and Randall E. Morris
J Immunol 2006 176: 1806-1813. [Abstract] [Full Text] [PDF]  

Costimulation Requirements for Antiviral CD8⁺ T Cells Differ for Acute and Persistent Phases of Polyoma Virus Infection

Christopher C. Kemball, Eun D. Han Lee, Eva Szomolanyi-Tsuda, Thomas C. Pearson, Christian P. Larsen, and Aron E. Lukacher
J Immunol 2006 176: 1814-1824. [Abstract] [Full Text] [PDF]  

Inhibition of TCR Signaling by Herpes Simplex Virus

Derek D. Sloan, Jin-Young Han, Tracy K. Sandifer, Mary Stewart, Aaron J. Hinz, Miri Yoon, David C. Johnson, Patricia G. Spear, and Keith R. Jerome
J Immunol 2006 176: 1825-1833. [Abstract] [Full Text] [PDF]  

Mimicry of Apoptotic Cells by Exposing Phosphatidylserine Participates in the Establishment of Amastigotes of Leishmania (L) amazonensis in Mammalian Hosts

João L. M. Wanderley, Maria E. C. Moreira, Aline Benjamin, Adriana C. Bonomo, and Marcello A. Barcinski
J Immunol 2006 176: 1834-1839. [Abstract] [Full Text] [PDF]  

Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN- Signaling

Stefan Zimmermann, Peter J. Murray, Klaus Heeg, and Alexander H. Dalpke
J Immunol 2006 176: 1840-1847. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes

Charles N. Serhan, Katherine Gotlinger, Song Hong, Yan Lu, Jeffrey Siegelman, Tamara Baer, Rong Yang, Sean P. Colgan, and Nicos A. Petasis
J Immunol 2006 176: 1848-1859. [Abstract] [Full Text] [PDF]  

Fraktalkine Produced by Airway Smooth Muscle Cells Contributes to Mast Cell Recruitment in Asthma

Amr El-Shazly, Patrick Berger, Pierre-Olivier Girodet, Olga Ousova, Michael Fayon, Jean-Marc Vernejoux, Roger Marthan, and J. Manuel Tunon-de-Lara
J Immunol 2006 176: 1860-1868. [Abstract] [Full Text] [PDF]  

Corticotropin-Releasing Factor and the Urocortins Induce the Expression of TLR4 in Macrophages via Activation of the Transcription Factors PU.1 and AP-1

Christos Tsatsanis, Ariadne Androulidaki, Themis Alissafi, Ioannis Charalampopoulos, Erini Dermitzaki, Thierry Roger, Achille Gravanis, and Andrew N. Margioris
J Immunol 2006 176: 1869-1877. [Abstract] [Full Text] [PDF]  

Lipoxin A₄ Redistributes Myosin IIA and Cdc42 in Macrophages: Implications for Phagocytosis of Apoptotic Leukocytes

Keira Reville, John K. Crean, Sharon Vivers, Ian Dransfield, and Catherine Godson
J Immunol 2006 176: 1878-1888. [Abstract] [Full Text] [PDF]  

Proinflammatory Effects of Tweak/Fn14 Interactions in Glomerular Mesangial Cells

Sean Campbell, Linda C. Burkly, Hua-Xin Gao, Joan W. Berman, Lihe Su, Beth Browning, Timothy Zheng, Lena Schiffer, Jennifer S. Michaelson, and Chaim Putterman
J Immunol 2006 176: 1889-1898. [Abstract] [Full Text] [PDF]  

Essential Role of MAPK Phosphatase-1 in the Negative Control of Innate Immune Responses

Konstantin V. Salojin, Iris B. Owusu, Karen A. Millerchip, Mark Potter, Ken A. Platt, and Tamas Oravecz
J Immunol 2006 176: 1899-1907. [Abstract] [Full Text] [PDF]  

In Vitro and In Situ Expression of IL-23 by Keratinocytes in Healthy Skin and Psoriasis Lesions: Enhanced Expression in Psoriatic Skin

Gamze Piskin, Regien M. R. Sylva-Steenland, Jan D. Bos, and Marcel B. M. Teunissen
J Immunol 2006 176: 1908-1915. [Abstract] [Full Text] [PDF]  

Circulating Progenitor Epithelial Cells Traffic via CXCR4/CXCL12 in Response to Airway Injury

Brigitte N. Gomperts, John A. Belperio, P. Nagesh Rao, Scott H. Randell, Michael C. Fishbein, Marie D. Burdick, and Robert M. Strieter
J Immunol 2006 176: 1916-1927. [Abstract] [Full Text] [PDF]  

Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation

Wataru Matsuyama, Masaki Watanabe, Yuko Shirahama, Ryuki Hirano, Hideo Mitsuyama, Ikkou Higashimoto, Mistuhiro Osame, and Kimiyoshi Arimura
J Immunol 2006 176: 1928-1936. [Abstract] [Full Text] [PDF]  

Deletion of TLR3 Alters the Pulmonary Immune Environment and Mucus Production during Respiratory Syncytial Virus Infection

Brian D. Rudd, Jetse J. Smit, Richard A. Flavell, Lena Alexopoulou, Matthew A. Schaller, Achim Gruber, Aaron A. Berlin, and Nicholas W. Lukacs
J Immunol 2006 176: 1937-1942. [Abstract] [Full Text] [PDF]  

Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine Model

Esther López, Victoria del Pozo, Teresa Miguel, Beatriz Sastre, Carmen Seoane, Esther Civantos, Elena Llanes, M. Luisa Baeza, Pilar Palomino, Blanca Cárdaba, Soledad Gallardo, Félix Manzarbeitia, José M. Zubeldia, and Carlos Lahoz
J Immunol 2006 176: 1943-1950. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Redundancy in Antigen-Presenting Function of the HLA-DR and -DQ Molecules in the Multiple Sclerosis-Associated HLA-DR2 Haplotype

Mireia Sospedra, Paolo A. Muraro, Irena Stefanová, Yingdong Zhao, Katherine Chung, Yili Li, Marc Giulianotti, Richard Simon, Roy Mariuzza, Clemencia Pinilla, and Roland Martin
J Immunol 2006 176: 1951-1961. [Abstract] [Full Text] [PDF]  

Effacing of the T Cell Compartment by Cardiac Transplantation in Infancy

Brenda M. Ogle, Lori J. West, David J. Driscoll, Scott E. Strome, Raymund R. Razonable, Carlos V. Paya, Marilia Cascalho, and Jeffrey L. Platt
J Immunol 2006 176: 1962-1967. [Abstract] [Full Text] [PDF]  

Identification of an Epitope within Human Integrin ₆ Subunit for the Binding of Autoantibody and Its Role in Basement Membrane Separation in Oral Pemphigoid

Khwaja Aftab Rashid, Joel N. H. Stern, and A. Razzaque Ahmed
J Immunol 2006 176: 1968-1977. [Abstract] [Full Text] [PDF]  

TLR9 Activation Is Defective in Common Variable Immune Deficiency

Charlotte Cunningham-Rundles, Lin Radigan, Adina K. Knight, Li Zhang, Laura Bauer, and Atsushi Nakazawa
J Immunol 2006 176: 1978-1987. [Abstract] [Full Text] [PDF]  

Allelic Variation in Key Peptide-Binding Pockets Discriminates between Closely Related Diabetes-Protective and Diabetes-Susceptible HLA-DQB1*06 Alleles

Ruth A. Ettinger, George K. Papadopoulos, Antonis K. Moustakas, Gerald T. Nepom, and William W. Kwok
J Immunol 2006 176: 1988-1998. [Abstract] [Full Text] [PDF]  

Predicting Tumor Outcome following Cancer Vaccination by Monitoring Quantitative and Qualitative CD8⁺ T Cell Parameters

Antonio Rosato, Alessia Zoso, Silvia Dalla Santa, Gabriella Milan, Paola Del Bianco, Gian Luca De Salvo, and Paola Zanovello
J Immunol 2006 176: 1999-2006. [Abstract] [Full Text] [PDF]  

Pretreatment Intracerebral and Peripheral Blood Immune Responses in Vietnamese Adults with Tuberculous Meningitis: Diagnostic Value and Relationship to Disease Severity and Outcome

Cameron P. Simmons, Guy E. Thwaites, Nguyen Than Ha Quyen, Estee Torok, Dang Minh Hoang, Tran Thi Hong Chau, Pham Phuong Mai, Nguyen Thi Ngoc Lan, Nguyen Huy Dung, Hoang Thi Quy, Nguyen Duc Bang, Tran Tinh Hien, and Jeremy Farrar
J Immunol 2006 176: 2007-2014. [Abstract] [Full Text] [PDF]  

Autoreactive T and B Cells from Bullous Pemphigoid (BP) Patients Recognize Epitopes Clustered in Distinct Regions of BP180 and BP230

Sybille Thoma-Uszynski, Wolfgang Uter, Susanne Schwietzke, Gerold Schuler, Luca Borradori, and Michael Hertl
J Immunol 2006 176: 2015-2023. [Abstract] [Full Text] [PDF]  

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