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On the cover: Crypt hyperplasia, villus atrophy, and goblet cell hyperplasia (pink/purple cells) of the small intestine (jejunum) of SCID mice following infection by the nematode Trichinella spiralis. The intestinal pathology observed is mediated by resident intraepithelial NK cells through the release of IL-13. McDermott, J. R., N. E. Humphreys, S. P. Forman, D. D. Donaldson, and R. K. Grencis. 2005. Intraepithelial NK cell-derived IL-13 induces intestinal pathology associated with nematode infection. J. Immunol. 175: 3207-3213.
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