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Contents: Volume 173 / No. 2 / July 15, 2004   [Index by Author] 
       IN THIS ISSUE
       BRIEF REVIEWS
       CUTTING EDGE
       CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
       MOLECULAR AND STRUCTURAL IMMUNOLOGY
       HOST DEFENSE
       INFLAMMATION
       CLINICAL IMMUNOLOGY
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IN THIS ISSUE:

IN THIS ISSUE

J Immunol 2004 173: 713-714. [Full Text] [PDF]  

BRIEF REVIEWS:

Understanding the Pro- and Anti-Inflammatory Properties of IL-27
Alejandro V. Villarino, Elaine Huang, and Christopher A. Hunter
J Immunol 2004 173: 715-720. [Abstract] [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Pulmonary Immunopathology Mediated by Antigen-Specific Expression of TNF-{alpha} by Antiviral CD8+ T Cells
Lumei Xu, Heesik Yoon, Min Q. Zhao, Jun Liu, Chilakamarti V. Ramana, and Richard I. Enelow
J Immunol 2004 173: 721-725. [Abstract] [Full Text] [PDF]  

Cutting Edge: Selective Requirement for the Wiskott-Aldrich Syndrome Protein in Cytokine, but Not Chemokine, Secretion by CD4+ T Cells
Vanessa Morales-Tirado, Sara Johannson, Elaine Hanson, Alan Howell, Jinyi Zhang, Katherine A. Siminovitch, and Deborah J. Fowell
J Immunol 2004 173: 726-730. [Abstract] [Full Text] [PDF]  

Cutting Edge: Induction of the Antigen-Processing Enzyme IFN-{gamma}-Inducible Lysosomal Thiol Reductase in Melanoma Cells Is STAT1-Dependent but CIITA-Independent
Patrick W. O’Donnell, Azizul Haque, Michael J. Klemsz, Mark H. Kaplan, and Janice S. Blum
J Immunol 2004 173: 731-735. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Cell Proliferation and STAT6 Pathways Are Negatively Regulated in T Cells by STAT1 and Suppressors of Cytokine Signaling
Cheng-Rong Yu, Rashid M. Mahdi, Samuel Ebong, Barbara P. Vistica, Jun Chen, Yonghong Guo, Igal Gery, and Charles E. Egwuagu
J Immunol 2004 173: 737-746. [Abstract] [Full Text] [PDF]  

C3a and C3b Activation Products of the Third Component of Complement (C3) Are Critical for Normal Liver Recovery after Toxic Injury
Maciej M. Markiewski, Dimitrios Mastellos, Ruxandra Tudoran, Robert A. DeAngelis, Christoph W. Strey, Silvia Franchini, Rick A. Wetsel, Anna Erdei, and John D. Lambris
J Immunol 2004 173: 747-754. [Abstract] [Full Text] [PDF]  

Cholera Toxin Prevents Th1-Mediated Autoimmune Disease by Inducing Immune Deviation
Shao- Bo Su, Phyllis B. Silver, Peng Wang, Chi-Chao Chan, and Rachel R. Caspi
J Immunol 2004 173: 755-761. [Abstract] [Full Text] [PDF]  

Role of Gut-Associated Lymphoreticular Tissues in Antigen-Specific Intestinal IgA Immunity
Masafumi Yamamoto, Mi-Na Kweon, Paul D. Rennert, Takachika Hiroi, Kohtaro Fujihashi, Jerry R. McGhee, and Hiroshi Kiyono
J Immunol 2004 173: 762-769. [Abstract] [Full Text] [PDF]  

Tec Kinase Migrates to the T Cell-APC Interface Independently of Its Pleckstrin Homology Domain
Fabien Garçon, Georges Bismuth, Daniel Isnardon, Daniel Olive, and Jacques A. Nunès
J Immunol 2004 173: 770-775. [Abstract] [Full Text] [PDF]  

K+ Channel Expression during B Cell Differentiation: Implications for Immunomodulation and Autoimmunity
Heike Wulff, Hans-Günther Knaus, Michael Pennington, and K. George Chandy
J Immunol 2004 173: 776-786. [Abstract] [Full Text] [PDF]  

Expression of the B7.1 Costimulatory Molecule on Pancreatic {beta} Cells Abrogates the Requirement for CD4 T Cells in the Development of Type 1 Diabetes
Evis Havari, Ana Maria Lennon-Dumenil, Ludger Klein, Devon Neely, Jacqueline A. Taylor, Marcia F. McInerney, Kai W. Wucherpfennig, and Myra A. Lipes
J Immunol 2004 173: 787-796. [Abstract] [Full Text] [PDF]  

Mechanism by Which Orally Administered {beta}-1,3-Glucans Enhance the Tumoricidal Activity of Antitumor Monoclonal Antibodies in Murine Tumor Models
Feng Hong, Jun Yan, Jarek T. Baran, Daniel J. Allendorf, Richard D. Hansen, Gary R. Ostroff, Pei Xiang Xing, Nai-Kong V. Cheung, and Gordon D. Ross
J Immunol 2004 173: 797-806. [Abstract] [Full Text] [PDF]  

B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells
Lai Guan Ng, Andrew P. R. Sutherland, Rebecca Newton, Fang Qian, Teresa G. Cachero, Martin L. Scott, Jeffrey S. Thompson, Julie Wheway, Tatyana Chtanova, Joanna Groom, Ian J. Sutton, Cynthia Xin, Stuart G. Tangye, Susan L. Kalled, Fabienne Mackay, and Charles R. Mackay
J Immunol 2004 173: 807-817. [Abstract] [Full Text] [PDF]  

Decreased E47 in Senescent B Cell Precursors Is Stage Specific and Regulated Posttranslationally by Protein Turnover
Elaine Van der Put, Daniela Frasca, Anne M. King, Bonnie B. Blomberg, and Richard L. Riley
J Immunol 2004 173: 818-827. [Abstract] [Full Text] [PDF]  

IL-10 Plays an Important Role in the Homeostatic Regulation of the Autoreactive Repertoire in Naive Mice
Ana C. Anderson, Jayagopala Reddy, Remedios Nazareno, Raymond A. Sobel, Lindsay B. Nicholson, and Vijay K. Kuchroo
J Immunol 2004 173: 828-834. [Abstract] [Full Text] [PDF]  

No Intrinsic Deficiencies in CD8+ T Cell-Mediated Antitumor Immunity with Aging
Lyse A. Norian and Paul M. Allen
J Immunol 2004 173: 835-844. [Abstract] [Full Text] [PDF]  

Differential Roles for CCR5 Expression on Donor T Cells during Graft-versus-Host Disease Based on Pretransplant Conditioning
Christian A. Wysocki, Susan B. Burkett, Angela Panoskaltsis-Mortari, Suzanne L. Kirby, Andrew D. Luster, Karen McKinnon, Bruce R. Blazar, and Jonathan S. Serody
J Immunol 2004 173: 845-854. [Abstract] [Full Text] [PDF]  

FTY720-Enhanced T Cell Homing Is Dependent on CCR2, CCR5, CCR7, and CXCR4: Evidence for Distinct Chemokine Compartments
Adam C. Yopp, Shuang Fu, Shaun M. Honig, Gwendalyn J. Randolph, Yaozhong Ding, Nancy R. Krieger, and Jonathan S. Bromberg
J Immunol 2004 173: 855-865. [Abstract] [Full Text] [PDF]  

Antigen-Specific Lymphocyte Sequestration in Lymphoid Organs: Lack of Essential Roles for {alpha}L and {alpha}4 Integrin-Dependent Adhesion or G{alpha}i Protein-Coupled Receptor Signaling
Carrie N. Arnold, Eugene C. Butcher, and Daniel J. Campbell
J Immunol 2004 173: 866-873. [Abstract] [Full Text] [PDF]  

Nitric Oxide Regulates Immune Cell Bioenergetic: A Mechanism to Understand Immunomodulatory Functions of Nitric Oxide-Releasing Anti-Inflammatory Drugs
Stefano Fiorucci, Andrea Mencarelli, Eleonora Distrutti, Monia Baldoni, Piero del Soldato, and Antonio Morelli
J Immunol 2004 173: 874-882. [Abstract] [Full Text] [PDF]  

Bcl6 Acts as an Amplifier for the Generation and Proliferative Capacity of Central Memory CD8+ T Cells
Hirohito Ichii, Akemi Sakamoto, Yoshikazu Kuroda, and Takeshi Tokuhisa
J Immunol 2004 173: 883-891. [Abstract] [Full Text] [PDF]  

Human B Cells Express Functional TRAIL/Apo-2 Ligand after CpG-Containing Oligodeoxynucleotide Stimulation
Troy J. Kemp, Jill M. Moore, and Thomas S. Griffith
J Immunol 2004 173: 892-899. [Abstract] [Full Text] [PDF]  

IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21
Adrianna Moroz, Cheryl Eppolito, Qingsheng Li, Jianming Tao, Christopher H. Clegg, and Protul A. Shrikant
J Immunol 2004 173: 900-909. [Abstract] [Full Text] [PDF]  

Differential Requirement for IFN-{gamma} in CTL Maturation in Acute Murine Graft-versus-Host Disease
Roman Puliaev, Phuong Nguyen, Fred D. Finkelman, and Charles S. Via
J Immunol 2004 173: 910-919. [Abstract] [Full Text] [PDF]  

Rap1 Signaling Is Required for Suppression of Ras-Generated Reactive Oxygen Species and Protection Against Oxidative Stress in T Lymphocytes
Philip H. J. Remans, Sonja I. Gringhuis, Jacob M. van Laar, Marjolein E. Sanders, Ellen A. M. Papendrecht-van der Voort, Fried J. T. Zwartkruis, E. W. Nivine Levarht, Marcela Rosas, Paul J. Coffer, Ferdinand C. Breedveld, Johannes L. Bos, Paul P. Tak, Cornelis L. Verweij, and Kris A. Reedquist
J Immunol 2004 173: 920-931. [Abstract] [Full Text] [PDF]  

Adenosine Acts through A2 Receptors to Inhibit IL-2-Induced Tyrosine Phosphorylation of STAT5 in T Lymphocytes: Role of Cyclic Adenosine 3',5'-Monophosphate and Phosphatases
Hong Zhang, David M. Conrad, Jared J. Butler, Chuanli Zhao, Jonathan Blay, and David W. Hoskin
J Immunol 2004 173: 932-944. [Abstract] [Full Text] [PDF]  

SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
Jens M. Chemnitz, Richard V. Parry, Kim E. Nichols, Carl H. June, and James L. Riley
J Immunol 2004 173: 945-954. [Abstract] [Full Text] [PDF]  

T Cell Biasing by Activated Dendritic Cells
Charles F. Anderson, Mark Lucas, Laila Gutiérrez-Kobeh, Ann E. Field, and David M. Mosser
J Immunol 2004 173: 955-961. [Abstract] [Full Text] [PDF]  

TGF-{beta}1 Disrupts Endotoxin Signaling in Microglial Cells through Smad3 and MAPK Pathways
Yingying Le, Pablo Iribarren, Wanghua Gong, Youhong Cui, Xia Zhang, and Ji Ming Wang
J Immunol 2004 173: 962-968. [Abstract] [Full Text] [PDF]  

Fully Functional Memory CD8 T Cells in the Absence of CD4 T Cells
Amanda L. Marzo, Vaiva Vezys, Kimberly D. Klonowski, Seung-Joo Lee, Guruprasaadh Muralimohan, Meagan Moore, David F. Tough, and Leo Lefrançois
J Immunol 2004 173: 969-975. [Abstract] [Full Text] [PDF]  

Nucleolin Is a Second Component of the CD154 mRNA Stability Complex That Regulates mRNA Turnover in Activated T Cells
Karnail Singh, Jennifer Laughlin, Penelope A. Kosinski, and Lori R. Covey
J Immunol 2004 173: 976-985. [Abstract] [Full Text] [PDF]  

Kinase Suppressor of Ras Couples Ras to the ERK Cascade during T Cell Development
Micheline N. Laurent, Danny Maria Ramirez, and José Alberola-Ila
J Immunol 2004 173: 986-992. [Abstract] [Full Text] [PDF]  

FcR Interactions Do Not Play a Major Role in Inhibition of Experimental Autoimmune Encephalomyelitis by Anti-CD154 Monoclonal Antibodies
Lex Nagelkerken, Inge Haspels, Wouter van Rijs, Bep Blauw, Janine L. Ferrant, Donna M. Hess, Ellen A. Garber, Fred R. Taylor, and Linda C. Burkly
J Immunol 2004 173: 993-999. [Abstract] [Full Text] [PDF]  

Basal Ig{alpha}/Ig{beta} Signals Trigger the Coordinated Initiation of Pre-B Cell Antigen Receptor-Dependent Processes
Ezequiel M. Fuentes-Pananá, Gregory Bannish, Neelima Shah, and John G. Monroe
J Immunol 2004 173: 1000-1011. [Abstract] [Full Text] [PDF]  

T Cell Immunity Induced by Live, Necrotic, and Apoptotic Tumor Cells
Wolf C. Bartholomae, Frauke H. Rininsland, Julia C. Eisenberg, Bernhard O. Boehm, Paul V. Lehmann, and Magdalena Tary-Lehmann
J Immunol 2004 173: 1012-1022. [Abstract] [Full Text] [PDF]  

A Tumor-Associated Glycoprotein That Blocks MHC Class II-Dependent Antigen Presentation by Dendritic Cells
Ralf Gutzmer, Wei Li, Shaheen Sutterwala, Maria P. Lemos, J. Ignasi Elizalde, Sandra L. Urtishak, Edward M. Behrens, Patricia M. Rivers, Katia Schlienger, Terri M. Laufer, Stephen L. Eck, and Michael S. Marks
J Immunol 2004 173: 1023-1032. [Abstract] [Full Text] [PDF]  

Specific Engagement of TLR4 or TLR3 Does Not Lead to IFN-{beta}-Mediated Innate Signal Amplification and STAT1 Phosphorylation in Resident Murine Alveolar Macrophages
Antonello Punturieri, Rebecca S. Alviani, Timothy Polak, Phil Copper, Joanne Sonstein, and Jeffrey L. Curtis
J Immunol 2004 173: 1033-1042. [Abstract] [Full Text] [PDF]  

Oral Tolerance to Nickel Requires CD4+ Invariant NKT Cells for the Infectious Spread of Tolerance and the Induction of Specific Regulatory T Cells
Karin Roelofs-Haarhuis, Xianzhu Wu, and Ernst Gleichmann
J Immunol 2004 173: 1043-1050. [Abstract] [Full Text] [PDF]  

Requirements of NK Cells and Proinflammatory Cytokines in T Cell-Dependent Neonatal Autoimmune Ovarian Disease Triggered by Immune Complex
Yulius Y. Setiady, Patcharin Pramoonjago, and Kenneth S. K. Tung
J Immunol 2004 173: 1051-1058. [Abstract] [Full Text] [PDF]  

Resistance to CD4+CD25+ Regulatory T Cells and TGF-{beta} in Cbl-b–/– Mice
Elizabeth A. Wohlfert, Margaret K. Callahan, and Robert B. Clark
J Immunol 2004 173: 1059-1065. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

TNF Activates Syk Protein Tyrosine Kinase Leading to TNF-Induced MAPK Activation, NF-{kappa}B Activation, and Apoptosis
Yasunari Takada and Bharat B. Aggarwal
J Immunol 2004 173: 1066-1077. [Abstract] [Full Text] [PDF]  

Two Human ULBP/RAET1 Molecules with Transmembrane Regions Are Ligands for NKG2D
Louise Bacon, Robert A. Eagle, Martina Meyer, Nicholas Easom, Neil T. Young, and John Trowsdale
J Immunol 2004 173: 1078-1084. [Abstract] [Full Text] [PDF]  

Dissection of the HLA-DR4 Peptide Repertoire in Endocrine Epithelial Cells: Strong Influence of Invariant Chain and HLA-DM Expression on the Nature of Ligands
Aura Muntasell, Montserrat Carrascal, Iñaki Alvarez, Laurence Serradell, Peter van Veelen, Frank A. W. Verreck, Frits Koning, Joaquín Abian, and Dolores Jaraquemada
J Immunol 2004 173: 1085-1093. [Abstract] [Full Text] [PDF]  

Analysis of Transcription Factor Expression during Discrete Stages of Postnatal Thymocyte Differentiation
Sahba Tabrizifard, Alexandru Olaru, Jason Plotkin, Mohammad Fallahi-Sichani, Ferenc Livak, and Howard T. Petrie
J Immunol 2004 173: 1094-1102. [Abstract] [Full Text] [PDF] Data Supplement  

STAT1 Regulates Lipopolysaccharide- and TNF-{alpha}-Dependent Expression of Transporter Associated with Antigen Processing 1 and Low Molecular Mass Polypeptide 2 Genes in Macrophages by Distinct Mechanisms
Laura Marqués, Marina Brucet, Jorge Lloberas, and Antonio Celada
J Immunol 2004 173: 1103-1110. [Abstract] [Full Text] [PDF]  

The E2F-1 Transcription Factor Promotes Caspase-8 and Bid Expression, and Enhances Fas Signaling in T Cells
Qingyu Cao, Ying Xia, Mitra Azadniv, and I. Nicholas Crispe
J Immunol 2004 173: 1111-1117. [Abstract] [Full Text] [PDF]  

A Short Consensus Repeat-Containing Complement Regulatory Protein of Lamprey That Participates in Cleavage of Lamprey Complement 3
Yuko Kimura, Naokazu Inoue, Aya Fukui, Hiroyuki Oshiumi, Misako Matsumoto, Mayumi Nonaka, Shigeru Kuratani, Teizo Fujita, Masaru Nonaka, and Tsukasa Seya
J Immunol 2004 173: 1118-1128. [Abstract] [Full Text] [PDF]  

Unprecedented Multiplicity of Ig Transmembrane and Secretory mRNA Forms in the Cartilaginous Fish
Lynn L. Rumfelt, Marilyn Diaz, Rebecca L. Lohr, Evonne Mochon, and Martin F. Flajnik
J Immunol 2004 173: 1129-1139. [Abstract] [Full Text] [PDF]  

Peptide Variants of Viral CTL Epitopes Mediate Positive Selection and Emigration of Ag-Specific Thymocytes In Vivo
Masha Fridkis-Hareli, Pedro A. Reche, and Ellis L. Reinherz
J Immunol 2004 173: 1140-1150. [Abstract] [Full Text] [PDF]  

Tyrosine Kinase 2 Interacts with and Phosphorylates Receptor for Activated C Kinase-1, a WD Motif-Containing Protein
Takashi Haro, Kazuya Shimoda, Haruko Kakumitsu, Kenjirou Kamezaki, Akihiko Numata, Fumihiko Ishikawa, Yuichi Sekine, Ryuta Muromoto, Tadashi Matsuda, and Mine Harada
J Immunol 2004 173: 1151-1157. [Abstract] [Full Text] [PDF]  

Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation
Chainarong Tunyaplin, A. L. Shaffer, Cristina D. Angelin-Duclos, Xin Yu, Louis M. Staudt, and Kathryn L. Calame
J Immunol 2004 173: 1158-1165. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

TLR4 Is the Signaling but Not the Lipopolysaccharide Uptake Receptor
Stefan Dunzendorfer, Hyun-Ku Lee, Katrin Soldau, and Peter S. Tobias
J Immunol 2004 173: 1166-1170. [Abstract] [Full Text] [PDF]  

Suppression of Ongoing Adjuvant-Induced Arthritis by Neutralizing the Function of the p28 Subunit of IL-27
Ruth Goldberg, Gizi Wildbaum, Yaniv Zohar, Gila Maor, and Nathan Karin
J Immunol 2004 173: 1171-1178. [Abstract] [Full Text] [PDF]  

TLR9 Is Localized in the Endoplasmic Reticulum Prior to Stimulation
Cynthia A. Leifer, Margaret N. Kennedy, Alessandra Mazzoni, ChangWoo Lee, Michael J. Kruhlak, and David M. Segal
J Immunol 2004 173: 1179-1183. [Abstract] [Full Text] [PDF]  

Role of IFN Regulatory Factor-1 and IL-12 in Immunological Resistance to Pathogenesis of N-Methyl-N-Nitrosourea-Induced T Lymphoma
Jianguo Liu, Zhaoying Xiang, and Xiaojing Ma
J Immunol 2004 173: 1184-1193. [Abstract] [Full Text] [PDF]  

Engagement of the Pathogen Survival Response Used by Group A Streptococcus to Avert Destruction by Innate Host Defense
Jovanka M. Voyich, Kevin R. Braughton, Daniel E. Sturdevant, Cuong Vuong, Scott D. Kobayashi, Stephen F. Porcella, Michael Otto, James M. Musser, and Frank R. DeLeo
J Immunol 2004 173: 1194-1201. [Abstract] [Full Text] [PDF] Data Supplement  

Secretion of Intracellular IL-1 Receptor Antagonist (Type 1) Is Dependent on P2X7 Receptor Activation
Heather L. Wilson, Sheila E. Francis, Steven K. Dower, and David C. Crossman
J Immunol 2004 173: 1202-1208. [Abstract] [Full Text] [PDF]  

Activation, Differentiation, and Migration of Naive Virus-Specific CD8+ T Cells during Pulmonary Influenza Virus Infection
Christopher W. Lawrence and Thomas J. Braciale
J Immunol 2004 173: 1209-1218. [Abstract] [Full Text] [PDF]  

Microbial DNA Induces a Host Defense Reaction of Human Respiratory Epithelial Cells
Juliane Platz, Christoph Beisswenger, Alexander Dalpke, Rembert Koczulla, Olaf Pinkenburg, Claus Vogelmeier, and Robert Bals
J Immunol 2004 173: 1219-1223. [Abstract] [Full Text] [PDF]  

CD25+CD4+ Cells Contribute to Th2 Polarization during Helminth Infection by Suppressing Th1 Response Development
Amy S. McKee and Edward J. Pearce
J Immunol 2004 173: 1224-1231. [Abstract] [Full Text] [PDF]  

CD154 Signaling Regulates the Th1 Response to Herpes Simplex Virus-1 and Inflammation in Infected Corneas
Min Xu, Andrew J. Lepisto, and Robert L. Hendricks
J Immunol 2004 173: 1232-1239. [Abstract] [Full Text] [PDF]  

Schistosoma mansoni Worms Induce Anergy of T Cells via Selective Up-Regulation of Programmed Death Ligand 1 on Macrophages
Philip Smith, Caitriona M. Walsh, Niamh E. Mangan, Rosie E. Fallon, Jon R. Sayers, Andrew N. J. McKenzie, and Padraic G. Fallon
J Immunol 2004 173: 1240-1248. [Abstract] [Full Text] [PDF]  

Human Dendritic Cells Respond to Helicobacter pylori, Promoting NK Cell and Th1-Effector Responses In Vitro
Nadia Hafsi, Petra Voland, Susanne Schwendy, Roland Rad, Wolfgang Reindl, Markus Gerhard, and Christian Prinz
J Immunol 2004 173: 1249-1257. [Abstract] [Full Text] [PDF]  

Fluid Shear Regulates the Kinetics and Receptor Specificity of Staphylococcus aureus Binding to Activated Platelets
Parag Pawar, Pyong Kyun Shin, Shaker A. Mousa, Julia M. Ross, and Konstantinos Konstantopoulos
J Immunol 2004 173: 1258-1265. [Abstract] [Full Text] [PDF]  

Type I IFN Protects Permissive Macrophages from Legionella pneumophila Infection through an IFN-{gamma}-Independent Pathway
Giovanna Schiavoni, Claudia Mauri, Davide Carlei, Filippo Belardelli, Maddalena Castellani Pastoris, and Enrico Proietti
J Immunol 2004 173: 1266-1275. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Inhibition of Farnesyltransferase Prevents Collagen-Induced Arthritis by Down-Regulation of Inflammatory Gene Expression through Suppression of p21ras-Dependent NF-{kappa}B Activation
Hee-Jun Na, Seon-Jin Lee, Yun-Chul Kang, Young-Lai Cho, Woo-Dong Nam, Peter K. M. Kim, Kwon-Soo Ha, Hun-Taeg Chung, Hansoo Lee, Young-Guen Kwon, Jong Sung Koh, and Young-Myeong Kim
J Immunol 2004 173: 1276-1283. [Abstract] [Full Text] [PDF]  

The Lectin-Like Domain of Complement Receptor 3 Protects Endothelial Barrier Function from Activated Neutrophils
Vassiliki L. Tsikitis, Nicole A. Morin, Elizabeth O. Harrington, Jorge E. Albina, and Jonathan S. Reichner
J Immunol 2004 173: 1284-1291. [Abstract] [Full Text] [PDF]  

Differential Induction of IL-1{beta} and TNF by CD40 Ligand or Cellular Contact with Stimulated T Cells Depends on the Maturation Stage of Human Monocytes
Danielle Burger, Nicolas Molnarfi, Lyssia Gruaz, and Jean-Michel Dayer
J Immunol 2004 173: 1292-1297. [Abstract] [Full Text] [PDF]  

Induction and Maintenance of Airway Responsiveness to Allergen Challenge Are Determined at the Age of Initial Sensitization
Erwin W. Gelfand, Anthony Joetham, Zhi-Hua Cui, Annette Balhorn, Katsuyuki Takeda, Christian Taube, and Azzeddine Dakhama
J Immunol 2004 173: 1298-1306. [Abstract] [Full Text] [PDF]  

Pneumolysin-Induced Lung Injury Is Independent of Leukocyte Trafficking into the Alveolar Space
Ulrich A. Maus, Mrigank Srivastava, James C. Paton, Matthias Mack, M. Brett Everhart, Timothy S. Blackwell, John W. Christman, Detlef Schlöndorff, Werner Seeger, and Jürgen Lohmeyer
J Immunol 2004 173: 1307-1312. [Abstract] [Full Text] [PDF]  

TNF-Induced {beta}2 Integrin Activation Involves Src Kinases and a Redox-Regulated Activation of p38 MAPK
Mohamed Bouaouina, Eric Blouin, Lise Halbwachs-Mecarelli, Philippe Lesavre, and Philippe Rieu
J Immunol 2004 173: 1313-1320. [Abstract] [Full Text] [PDF]  

E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
Jennifer L. Goulet, Amy J. Pace, Mikelle L. Key, Robert S. Byrum, MyTrang Nguyen, Stephen L. Tilley, Scott G. Morham, Robert Langenbach, Jeffrey L. Stock, John D. McNeish, Oliver Smithies, Thomas M. Coffman, and Beverly H. Koller
J Immunol 2004 173: 1321-1326. [Abstract] [Full Text] [PDF]  

Immunoregulatory Role of Nitric Oxide in Kilham Rat Virus-Induced Autoimmune Diabetes in DR-BB Rats
Israel I. Mendez, Young-Hwa Chung, Hee-Sook Jun, and Ji-Won Yoon
J Immunol 2004 173: 1327-1335. [Abstract] [Full Text] [PDF]  

Regulation of Endotoxin-Induced Proinflammatory Activation in Human Coronary Artery Cells: Expression of Functional Membrane-Bound CD14 by Human Coronary Artery Smooth Muscle Cells
Lynn L. Stoll, Gerene M. Denning, Wei-Gen Li, James B. Rice, Allan L. Harrelson, Sara A. Romig, Skuli T. Gunnlaugsson, Francis J. Miller, Jr, and Neal L. Weintraub
J Immunol 2004 173: 1336-1343. [Abstract] [Full Text] [PDF]  

Antineuroinflammatory Effect of NF-{kappa}B Essential Modifier-Binding Domain Peptides in the Adoptive Transfer Model of Experimental Allergic Encephalomyelitis
Subhajit Dasgupta, Malabendu Jana, You Zhou, Yiu K. Fung, Sankar Ghosh, and Kalipada Pahan
J Immunol 2004 173: 1344-1354. [Abstract] [Full Text] [PDF]  

Regulatory Role of C5a on Macrophage Migration Inhibitory Factor Release from Neutrophils
Niels C. Riedemann, Ren-Feng Guo, Hongwei Gao, Lei Sun, Marco Hoesel, Travis J. Hollmann, Rick A. Wetsel, Firas S. Zetoune, and Peter A. Ward
J Immunol 2004 173: 1355-1359. [Abstract] [Full Text] [PDF]  

Blockade of Allergic Airway Inflammation Following Systemic Treatment with a B7-Dendritic Cell (PD-L2) Cross-Linking Human Antibody
Suresh Radhakrishnan, Koji Iijima, Takao Kobayashi, Moses Rodriguez, Hirohito Kita, and Larry R. Pease
J Immunol 2004 173: 1360-1365. [Abstract] [Full Text] [PDF]  

An Advanced Intercross Line Resolves Eae18 into Two Narrow Quantitative Trait Loci Syntenic to Multiple Sclerosis Candidate Loci
Maja Jagodic, Kristina Becanovic, Jian Rong Sheng, Xingchen Wu, Liselotte Bäckdahl, Johnny C. Lorentzen, Erik Wallström, and Tomas Olsson
J Immunol 2004 173: 1366-1373. [Abstract] [Full Text] [PDF]  

Activated Ets2 Is Required for Persistent Inflammatory Responses in the Motheaten Viable Model
Guo Wei, Jianping Guo, Andrea I. Doseff, Donna F. Kusewitt, Albert K. Man, Robert G. Oshima, and Michael C. Ostrowski
J Immunol 2004 173: 1374-1379. [Abstract] [Full Text] [PDF]  

A3 Adenosine Receptor Signaling Contributes to Airway Inflammation and Mucus Production in Adenosine Deaminase-Deficient Mice
Hays W. J. Young, Jose G. Molina, Dawn Dimina, Hongyan Zhong, Marlene Jacobson, Lee-Nien L. Chan, Teh-Sheng Chan, James J. Lee, and Michael R. Blackburn
J Immunol 2004 173: 1380-1389. [Abstract] [Full Text] [PDF]  

Mucosal T Cells Bearing TCR{gamma}{delta} Play a Protective Role in Intestinal Inflammation
Kyoko Inagaki-Ohara, Takatoshi Chinen, Goro Matsuzaki, Atsuo Sasaki, Yukiko Sakamoto, Kenji Hiromatsu, Fukumi Nakamura-Uchiyama, Yukifumi Nawa, and Akihiko Yoshimura
J Immunol 2004 173: 1390-1398. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Blockade of Late Stages of Autoimmune Diabetes by Inhibition of the Receptor for Advanced Glycation End Products
Yali Chen, Shirley ShiDu Yan, John Colgan, Hui-Ping Zhang, Jeremy Luban, Ann Marie Schmidt, David Stern, and Kevan C. Herold
J Immunol 2004 173: 1399-1405. [Abstract] [Full Text] [PDF]  

Essential Role of MD-2 in TLR4-Dependent Signaling during Helicobacter pylori-Associated Gastritis
Shunji Ishihara, Mohammad Azharul Karim Rumi, Yasunori Kadowaki, Cesar Francisco Ortega-Cava, Takafumi Yuki, Nagisa Yoshino, Youichi Miyaoka, Hideaki Kazumori, Norihisa Ishimura, Yuji Amano, and Yoshikazu Kinoshita
J Immunol 2004 173: 1406-1416. [Abstract] [Full Text] [PDF]  

Production of Profibrotic Cytokines by Invariant NKT Cells Characterizes Cirrhosis Progression in Chronic Viral Hepatitis
Claudia de Lalla, Grazia Galli, Luca Aldrighetti, Raffaella Romeo, Margherita Mariani, Antonella Monno, Sandra Nuti, Massimo Colombo, Francesco Callea, Steven A. Porcelli, Paola Panina-Bordignon, Sergio Abrignani, Giulia Casorati, and Paolo Dellabona
J Immunol 2004 173: 1417-1425. [Abstract] [Full Text] [PDF]  

The Myelin-Associated Oligodendrocytic Basic Protein Region MOBP15–36 Encompasses the Immunodominant Major Encephalitogenic Epitope(s) for SJL/J Mice and Predicted Epitope(s) for Multiple Sclerosis-Associated HLA-DRB1*1501
Nicole Kerlero de Rosbo, Joel F. Kaye, Miriam Eisenstein, Itzhack Mendel, Romana Hoeftberger, Hans Lassmann, Roni Milo, and Avraham Ben-Nun
J Immunol 2004 173: 1426-1435. [Abstract] [Full Text] [PDF]  

Crisscross CTL Induction by SYT-SSX Junction Peptide and Its HLA-A*2402 Anchor Substitute
Kazunori Ida, Satoshi Kawaguchi, Yuriko Sato, Tomohide Tsukahara, Yuki Nabeta, Hiroeki Sahara, Hideyuki Ikeda, Toshihiko Torigoe, Shingo Ichimiya, Kenjiro Kamiguchi, Takuro Wada, Satoshi Nagoya, Hiroaki Hiraga, Akira Kawai, Takeshi Ishii, Nobuhito Araki, Akira Myoui, Seiichi Matsumoto, Toshifumi Ozaki, Hideki Yoshikawa, Toshihiko Yamashita, and Noriyuki Sato
J Immunol 2004 173: 1436-1443. [Abstract] [Full Text] [PDF]  

Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells
Manuelle Viguier, Fabrice Lemaître, Olivier Verola, Min-Sun Cho, Guy Gorochov, Louis Dubertret, Hervé Bachelez, Philippe Kourilsky, and Laurent Ferradini
J Immunol 2004 173: 1444-1453. [Abstract] [Full Text] [PDF]  

Peritoneal Exudate Cells Treated with Calcitonin Gene-Related Peptide Suppress Murine Experimental Autoimmune Uveoretinitis via IL-10
Takeshi Kezuka, Masaru Takeuchi, Hiroshi Keino, Yoshihiko Usui, Aya Takeuchi, Noriyuki Yamakawa, and Masahiko Usui
J Immunol 2004 173: 1454-1462. [Abstract] [Full Text] [PDF]  

IL-15 and the Initiation of Cell Contact-Dependent Synovial Fibroblast-T Lymphocyte Cross-Talk in Rheumatoid Arthritis: Effect of Methotrexate
María-Eugenia Miranda-Carús, Alejandro Balsa, Marta Benito-Miguel, Carlos Pérez de Ayala, and Emilio Martín-Mola
J Immunol 2004 173: 1463-1476. [Abstract] [Full Text] [PDF]  

Chlamydia pneumoniae Stimulates IFN-{gamma} Synthesis through MyD88-Dependent, TLR2- and TLR4-Independent Induction of IL-18 Release
Mihai G. Netea, Bart Jan Kullberg, Liesbeth E. H. Jacobs, Trees J. G. Verver-Jansen, Johanna van der Ven-Jongekrijg, Jochem M. D. Galama, Anton F. H. Stalenhoef, Charles A. Dinarello, and Jos W. M. Van der Meer
J Immunol 2004 173: 1477-1482. [Abstract] [Full Text] [PDF]  

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