CUTTING EDGE:

Cutting Edge: IL-10-Producing CD4⁺ T Cells Mediate Tumor Rejection

Benjamin M. Segal, Deborah D. Glass, and Ethan M. Shevach
J Immunol 2002 168: 1-4. [Abstract] [Full Text] [PDF]  

Cutting Edge: CpG DNA Inhibits Dendritic Cell Apoptosis by Up-Regulating Cellular Inhibitor of Apoptosis Proteins Through the Phosphatidylinositide-3'-OH Kinase Pathway

Yunji Park, Seung Woo Lee, and Young Chul Sung
J Immunol 2002 168: 5-8. [Abstract] [Full Text] [PDF]  

Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease

Tetsuya Higuchi, Yuichi Aiba, Takashi Nomura, Junichiro Matsuda, Keiji Mochida, Misao Suzuki, Hitoshi Kikutani, Tasuku Honjo, Kiyoshi Nishioka, and Takeshi Tsubata
J Immunol 2002 168: 9-12. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Low-Affinity Anti-Smith Antigen B Cells Are Regulated by Anergy as Opposed to Developmental Arrest or Differentiation to B-1

Michelle Borrero and Stephen H. Clarke
J Immunol 2002 168: 13-21. [Abstract] [Full Text] [PDF]  

Contributions from Self-Renewal and Trafficking to the Uterine NK Cell Population of Early Pregnancy

Sirirak Chantakru, Craig Miller, Lindsay E. Roach, William A. Kuziel, Nobuyo Maeda, Wan-Chao Wang, Sharon S. Evans, and B. Anne Croy
J Immunol 2002 168: 22-28. [Abstract] [Full Text] [PDF]  

Development and Homeostasis of T Cell Memory in Rhesus Macaque

Christine J. Pitcher, Shoko I. Hagen, Joshua M. Walker, Richard Lum, Bridget L. Mitchell, Vernon C. Maino, Michael K. Axthelm, and Louis J. Picker
J Immunol 2002 168: 29-43. [Abstract] [Full Text] [PDF]  

Generation of Diversity in the Innate Immune System: Macrophage Heterogeneity Arises from Gene-Autonomous Transcriptional Probability of Individual Inducible Genes

Timothy Ravasi, Christine Wells, Alistair Forest, David M. Underhill, Brandon J. Wainwright, Alan Aderem, Sean Grimmond, and David A. Hume
J Immunol 2002 168: 44-50. [Abstract] [Full Text] [PDF]  

Immunostimulatory DNA Sequences Influence the Course of Adjuvant Arthritis

Arash Ronaghy, Berent J. Prakken, Kenji Takabayashi, Gary S. Firestein, David Boyle, Nathan J. Zvailfler, Sarah T. A. Roord, Salvatore Albani, Dennis A. Carson, and Eyal Raz
J Immunol 2002 168: 51-56. [Abstract] [Full Text] [PDF]  

Identification of Multiple Isolated Lymphoid Follicles on the Antimesenteric Wall of the Mouse Small Intestine

Hiromasa Hamada, Takachika Hiroi, Yasuhiro Nishiyama, Hidemi Takahashi, Yohei Masunaga, Satoshi Hachimura, Shuichi Kaminogawa, Hiromi Takahashi-Iwanaga, Toshihiko Iwanaga, Hiroshi Kiyono, Hiroshi Yamamoto, and Hiromichi Ishikawa
J Immunol 2002 168: 57-64. [Abstract] [Full Text] [PDF]  

Up-Regulation of CCR5 and CCR6 on Distinct Subpopulations of Antigen-Activated CD4⁺ T Lymphocytes

Lisa M. Ebert and Shaun R. McColl
J Immunol 2002 168: 65-72. [Abstract] [Full Text] [PDF]  

Requirement for NK Cells in CD40 Ligand-Mediated Rejection of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Cells

Tanja A. Gruber, Dianne C. Skelton, and Donald B. Kohn
J Immunol 2002 168: 73-80. [Abstract] [Full Text] [PDF]  

Impaired Development of T Lymphoid Precursors from Pluripotent Hematopoietic Stem Cells in New Zealand Black Mice

Yoshiko Hashimoto, Encarnacion Montecino-Rodriguez, M. Eric Gershwin, and Kenneth Dorshkind
J Immunol 2002 168: 81-86. [Abstract] [Full Text] [PDF]  

The Generation of Mature, Single-Positive Thymocytes In Vivo Is Dysregulated by CD69 Blockade or Overexpression

Toshinori Nakayama, Deborah J. Kasprowicz, Masakatsu Yamashita, Lisa A. Schubert, Geoffery Gillard, Motoko Kimura, Arnaud Didierlaurent, Haruhiko Koseki, and Steven F. Ziegler
J Immunol 2002 168: 87-94. [Abstract] [Full Text] [PDF]  

NK Cell Activation by Dendritic Cells Is Dependent on LFA-1-Mediated Induction of Calcium-Calmodulin Kinase II: Inhibition by HIV-1 Tat C-Terminal Domain

Alessandro Poggi, Roberta Carosio, Grazia Maria Spaggiari, Claudio Fortis, Giuseppe Tambussi, Giacomo Dell’Antonio, Elena Dal Cin, Anna Rubartelli, and M. Raffaella Zocchi
J Immunol 2002 168: 95-101. [Abstract] [Full Text] [PDF]  

Human Immature Dendritic Cells Efficiently Bind and Take up Secretory IgA Without the Induction of Maturation

Heleen C. Heystek, Corinne Moulon, Andrea M. Woltman, Pierre Garonne, and Cees van Kooten
J Immunol 2002 168: 102-107. [Abstract] [Full Text] [PDF]  

Noncovalent Association with Stress Protein Facilitates Cross-Priming of CD8⁺ T Cells to Tumor Cell Antigens by Dendritic Cells

Robert Kammerer, Detlef Stober, Petra Riedl, Claude Oehninger, Reinhold Schirmbeck, and Jörg Reimann
J Immunol 2002 168: 108-117. [Abstract] [Full Text] [PDF]  

Ly-6A.2 Expression Regulates Antigen-Specific CD4⁺ T Cell Proliferation and Cytokine Production

S. Christine Henderson, Mihir M. Kamdar, and Anil Bamezai
J Immunol 2002 168: 118-126. [Abstract] [Full Text] [PDF]  

TCR Transmembrane Tyrosines Are Required for Pre-TCR Function

Lisa M. Spain and Pinghu Liu
J Immunol 2002 168: 127-133. [Abstract] [Full Text] [PDF]  

Characterization of CCR9 Expression and CCL25/Thymus-Expressed Chemokine Responsiveness During T Cell Development: CD3^highCD69⁺ Thymocytes and TCR⁺ Thymocytes Preferentially Respond to CCL25

Shoji Uehara, Kaimei Song, Joshua M. Farber, and Paul E. Love
J Immunol 2002 168: 134-142. [Abstract] [Full Text] [PDF]  

Immature and Mature CD8⁺ Dendritic Cells Prolong the Survival of Vascularized Heart Allografts

Peta J. O’Connell, Wei Li, Zhiliang Wang, Susan M. Specht, Alison J. Logar, and Angus W. Thomson
J Immunol 2002 168: 143-154. [Abstract] [Full Text] [PDF]  

Staphylokinase-Specific Cell-Mediated Immunity in Humans

Petra A. M. Warmerdam, Kristel Vanderlick, Petra Vandervoort, Heidi De Smedt, Stéphane Plaisance, Marc De Maeyer, and Désiré Collen
J Immunol 2002 168: 155-161. [Abstract] [Full Text] [PDF]  

The CD8 T Cell Compartment Plays a Dominant Role in the Deficiency of Brown-Norway Rats to Mount a Proper Type 1 Immune Response

Bastien Cautain, Jan Damoiseaux, Isabelle Bernard, Emmanuel Xystrakis, Emmanuelle Fournié, Peter van Breda Vriesman, Philippe Druet, and Abdelhadi Saoudi
J Immunol 2002 168: 162-170. [Abstract] [Full Text] [PDF]  

Lactobacilli Differentially Modulate Expression of Cytokines and Maturation Surface Markers in Murine Dendritic Cells

Hanne R. Christensen, Hanne Frøkiær, and James J. Pestka
J Immunol 2002 168: 171-178. [Abstract] [Full Text] [PDF]  

Chronic Soluble Antigen Sensitization Primes a Unique Memory/Effector T Cell Repertoire Associated with Th2 Phenotype Acquisition In Vivo

Gilles Foucras, Alexandra Gallard, Christiane Coureau, Jean-M. Kanellopoulos, and Jean-Charles Guéry
J Immunol 2002 168: 179-187. [Abstract] [Full Text] [PDF]  

Elevated NF-B Activation in Nonobese Diabetic Mouse Dendritic Cells Results in Enhanced APC Function

Brian Poligone, Donald J. Weaver, Jr., Pradip Sen, Albert S. Baldwin, Jr., and Roland Tisch
J Immunol 2002 168: 188-196. [Abstract] [Full Text] [PDF]  

Native HIV-1 Tat Protein Targets Monocyte-Derived Dendritic Cells and Enhances Their Maturation, Function, and Antigen-Specific T Cell Responses

Emanuele Fanales-Belasio, Sonia Moretti, Filomena Nappi, Giovanni Barillari, Fabiola Micheletti, Aurelio Cafaro, and Barbara Ensoli
J Immunol 2002 168: 197-206. [Abstract] [Full Text] [PDF]  

Dual Effect of CD85/Leukocyte Ig-Like Receptor-1/Ig-Like Transcript 2 and CD152 (CTLA-4) on Cytokine Production by Antigen-Stimulated Human T Cells

Daniele Saverino, Andrea Merlo, Silvia Bruno, Vito Pistoia, Carlo E. Grossi, and Ermanno Ciccone
J Immunol 2002 168: 207-215. [Abstract] [Full Text] [PDF]  

CD8 T Cells Inhibit IgE Via Dendritic Cell IL-12 Induction That Promotes Th1 T Cell Counter-Regulation

Matthew J. Thomas, Alistair Noble, Ela Sawicka, Philip W. Askenase, and David M. Kemeny
J Immunol 2002 168: 216-223. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Influence of the Isotype of the Light Chain on the Properties of IgG

Ramon F. Montaño and Sherie L. Morrison
J Immunol 2002 168: 224-231. [Abstract] [Full Text] [PDF]  

CD5-Negative Regulation of B Cell Receptor Signaling Pathways Originates from Tyrosine Residue Y429 Outside an Immunoreceptor Tyrosine-Based Inhibitory Motif

Hélène Gary-Gouy, Julie Harriague, Ali Dalloul, Emmanuel Donnadieu, and Georges Bismuth
J Immunol 2002 168: 232-239. [Abstract] [Full Text] [PDF]  

Conservation and Variation in Human and Common Chimpanzee CD94 and NKG2 Genes

Benny P. Shum, Laura R. Flodin, David G. Muir, Raja Rajalingam, Salim I. Khakoo, Sophia Cleland, Lisbeth A. Guethlein, Markus Uhrberg, and Peter Parham
J Immunol 2002 168: 240-252. [Abstract] [Full Text] [PDF]  

HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) Use the Same Anchor Residues for Binding an Immunodominant Peptide Derived from Human Type II Collagen

Edward F. Rosloniec, Karen B. Whittington, Dennis M. Zaller, and Andrew H. Kang
J Immunol 2002 168: 253-259. [Abstract] [Full Text] [PDF]  

Classical MHC Class I Genes Composed of Highly Divergent Sequence Lineages Share a Single Locus in Rainbow Trout (Oncorhynchus mykiss)

Kazuhiko Aoyagi, Johannes M. Dijkstra, Chun Xia, Ikuo Denda, Mitsuru Ototake, Keiichiro Hashimoto, and Teruyuki Nakanishi
J Immunol 2002 168: 260-273. [Abstract] [Full Text] [PDF]  

Prostaglandin E₂-Mediated Activation of HIV-1 Long Terminal Repeat Transcription in Human T Cells Necessitates CCAAT/Enhancer Binding Protein (C/EBP) Binding Sites in Addition to Cooperative Interactions Between C/EBP and Cyclic Adenosine 5'-Monophosphate Response Element Binding Protein

Nancy Dumais, Salim Bounou, Martin Olivier, and Michel J. Tremblay
J Immunol 2002 168: 274-282. [Abstract] [Full Text] [PDF]  

How H13 Histocompatibility Peptides Differing by a Single Methyl Group and Lacking Conventional MHC Binding Anchor Motifs Determine Self-Nonself Discrimination

David A. Ostrov, Matthew M. Roden, Wuxian Shi, Edith Palmieri, Gregory J. Christianson, Lisa Mendoza, Gilbert Villaflor, Darcie Tilley, Nilabh Shastri, Howard Grey, Steven C. Almo, Derry Roopenian, and Stanley G. Nathenson
J Immunol 2002 168: 283-289. [Abstract] [Full Text] [PDF]  

Mast Cell -Chymase Reduces IgE Recognition of Birch Pollen Profilin by Cleaving Antibody-Binding Epitopes

Matthew B. Mellon, Brendon T. Frank, and Kenneth C. Fang
J Immunol 2002 168: 290-297. [Abstract] [Full Text] [PDF]  

Ceramide-Rich Membrane Rafts Mediate CD40 Clustering

Heike Grassmé, Verena Jendrossek, Jürgen Bock, Andrea Riehle, and Erich Gulbins
J Immunol 2002 168: 298-307. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Complementary Adhesion Molecules Promote Neutrophil- Kupffer Cell Interaction and the Elimination of Bacteria Taken Up by the Liver

Stephen H. Gregory, Leslie P. Cousens, Nico van Rooijen, Ed A. Döpp, Timothy M. Carlos, and Edward J. Wing
J Immunol 2002 168: 308-315. [Abstract] [Full Text] [PDF]  

Regulation of Human -Defensin-2 in Gingival Epithelial Cells: The Involvement of Mitogen-Activated Protein Kinase Pathways, But Not the NF-B Transcription Factor Family

Suttichai Krisanaprakornkit, Janet R. Kimball, and Beverly A. Dale
J Immunol 2002 168: 316-324. [Abstract] [Full Text] [PDF]  

IFN- Secretion by Type 2 Predendritic Cells Up-Regulates MHC Class I in the HIV-1-Infected Thymus

Mary E. Keir, Cheryl A. Stoddart, Valerie Linquist-Stepps, Mary E. Moreno, and Joseph M. McCune
J Immunol 2002 168: 325-331. [Abstract] [Full Text] [PDF]  

Vaccine Protection Against Functional CTL Abnormalities in Simian Human Immunodeficiency Virus-Infected Rhesus Monkeys

Paul F. McKay, Jörn E. Schmitz, Dan H. Barouch, Marcelo J. Kuroda, Michelle A. Lifton, Christine E. Nickerson, Darci A. Gorgone, and Norman L. Letvin
J Immunol 2002 168: 332-337. [Abstract] [Full Text] [PDF]  

Intensity of the Vaccine-Elicited Immune Response Determines Tumor Clearance

Ainhoa Perez-Diez, Paul J. Spiess, Nicholas P. Restifo, Polly Matzinger, and Francesco M. Marincola
J Immunol 2002 168: 338-347. [Abstract] [Full Text] [PDF]  

Toll-Like Receptor 2 Is Required for Innate, But Not Acquired, Host Defense to Borrelia burgdorferi

R. Mark Wooten, Ying Ma, R. Alyson Yoder, Jeanette P. Brown, John H. Weis, James F. Zachary, Carsten J. Kirschning, and Janis J. Weis
J Immunol 2002 168: 348-355. [Abstract] [Full Text] [PDF]  

Acquired Immune Responses to Plasmodium falciparum Merozoite Surface Protein-1 in the Human Fetus

Christopher L. King, Indu Malhotra, Alex Wamachi, John Kioko, Peter Mungai, Sherif Abdel Wahab, Davy Koech, Peter Zimmerman, John Ouma, and James W. Kazura
J Immunol 2002 168: 356-364. [Abstract] [Full Text] [PDF]  

Natural Killer T Cells Restricted by the Monomorphic MHC Class 1b CD1d1 Molecules Behave Like Inflammatory Cells

Martin Mempel, Catherine Ronet, Felipe Suarez, Martine Gilleron, Germain Puzo, Luc Van Kaer, Agnès Lehuen, Philippe Kourilsky, and Gabriel Gachelin
J Immunol 2002 168: 365-371. [Abstract] [Full Text] [PDF]  

IL-18 Improves the Early Antimicrobial Host Response to Pneumococcal Pneumonia

Fanny N. Lauw, Judith Branger, Sandrine Florquin, Peter Speelman, Sander J. H. van Deventer, Shizuo Akira, and Tom van der Poll
J Immunol 2002 168: 372-378. [Abstract] [Full Text] [PDF]  

Generation of Genome-Wide CD8 T Cell Responses in HLA-A*0201 Transgenic Mice by an HIV-1 Ubiquitin Expression Library Immunization Vaccine

Rana A. K. Singh, Lei Wu, and Michael A. Barry
J Immunol 2002 168: 379-391. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Colony-Stimulating Factor-1 Suppresses Responses to CpG DNA and Expression of Toll-Like Receptor 9 but Enhances Responses to Lipopolysaccharide in Murine Macrophages

Matthew J. Sweet, Carol C. Campbell, David P. Sester, Damo Xu, Rebecca C. McDonald, Katryn J. Stacey, David A. Hume, and Foo Y. Liew
J Immunol 2002 168: 392-399. [Abstract] [Full Text] [PDF]  

A Role for the Rho-p160 Rho Coiled-Coil Kinase Axis in the Chemokine Stromal Cell-Derived Factor-1-Induced Lymphocyte Actomyosin and Microtubular Organization and Chemotaxis

Miguel Vicente-Manzanares, José Román Cabrero, Mercedes Rey, Manuel Pérez-Martínez, Angeles Ursa, Kazuyuki Itoh, and Francisco Sánchez-Madrid
J Immunol 2002 168: 400-410. [Abstract] [Full Text] [PDF]  

Treatment of T Cell-Dependent Experimental Colitis in SCID Mice by Local Administration of an Adenovirus Expressing IL-18 Antisense mRNA

Stefan Wirtz, Christoph Becker, Richard Blumberg, Peter R. Galle, and Markus F. Neurath
J Immunol 2002 168: 411-420. [Abstract] [Full Text] [PDF]  

Role of STAT6 in IgE Receptor/FcRI-Mediated Late Phase Allergic Responses of Mast Cells

Ravi Malaviya and Fatih M. Uckun
J Immunol 2002 168: 421-426. [Abstract] [Full Text] [PDF]  

The Protective Role of Nitric Oxide in a Neurotoxicant- Induced Demyelinating Model

Heather A. Arnett, Ron P. Hellendall, Glenn K. Matsushima, Kinuko Suzuki, Victor E. Laubach, Paula Sherman, and Jenny P.-Y. Ting
J Immunol 2002 168: 427-433. [Abstract] [Full Text] [PDF]  

Bacterial Lipopolysaccharide Selectively Up-Regulates the Function of the Chemotactic Peptide Receptor Formyl Peptide Receptor 2 in Murine Microglial Cells

You-Hong Cui, Yingying Le, Wanghua Gong, Paul Proost, Jo Van Damme, William J. Murphy, and Ji Ming Wang
J Immunol 2002 168: 434-442. [Abstract] [Full Text] [PDF]  

Pronounced Eosinophilic Lung Inflammation and Th2 Cytokine Release in Human Lipocalin-Type Prostaglandin D Synthase Transgenic Mice

Yasushi Fujitani, Yoshihide Kanaoka, Kosuke Aritake, Nobuko Uodome, Kazue Okazaki-Hatake, and Yoshihiro Urade
J Immunol 2002 168: 443-449. [Abstract] [Full Text] [PDF]  

Fibroblast Growth Factor-2 Determines Severity of Joint Disease in Adjuvant-Induced Arthritis in Rats

Akihisa Yamashita, Yoshikazu Yonemitsu, Shinji Okano, Kazunori Nakagawa, Yutaka Nakashima, Takahiko Irisa, Yukihide Iwamoto, Yoshiyuki Nagai, Mamoru Hasegawa, and Katsuo Sueishi
J Immunol 2002 168: 450-457. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

Richard J. Mead, Sim K. Singhrao, James W. Neal, H. Lassmann, and B. Paul Morgan
J Immunol 2002 168: 458-465. [Abstract] [Full Text] [PDF]  

Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma

Qian Zhang, Puthryaveett N. Raghunath, Liquan Xue, Miroslaw Majewski, David F. Carpentieri, Niels Odum, Stephan Morris, Tomasz Skorski, and Mariusz A. Wasik
J Immunol 2002 168: 466-474. [Abstract] [Full Text] [PDF]  

ICA69^null Nonobese Diabetic Mice Develop Diabetes, but Resist Disease Acceleration by Cyclophosphamide

Shawn Winer, Igor Astsaturov, Roger Gaedigk, Denise Hammond-McKibben, Marc Pilon, Aihua Song, Violetta Kubiak, Wolfram Karges, Enrico Arpaia, Colin McKerlie, Peter Zucker, Bhagirath Singh, and H.-Michael Dosch
J Immunol 2002 168: 475-482. [Abstract] [Full Text] [PDF]  

Prolonged Allograft Survival in TNF Receptor 1-Deficient Recipients Is Due to Immunoregulatory Effects, Not to Inhibition of Direct Antigraft Cytotoxicity

Charlotte M. McKee, Rachel Defina, Hongzhen He, Kathleen J. Haley, James R. Stone, and David L. Perkins
J Immunol 2002 168: 483-489. [Abstract] [Full Text] [PDF]  

Detection of Early Changes in Autoimmune T Cell Phenotype and Function Following Intravenous Administration of Type II Collagen in a TCR-Transgenic Model

David D. Brand, Linda K. Myers, Karen B. Whittington, Kary A. Latham, John M. Stuart, Andrew H. Kang, and Edward F. Rosloniec
J Immunol 2002 168: 490-498. [Abstract] [Full Text] [PDF]  

Association of Prolonged Survival in HLA-A2⁺ Progressive Multifocal Leukoencephalopathy Patients with a CTL Response Specific for a Commonly Recognized JC Virus Epitope

Igor J. Koralnik, Renaud A. Du Pasquier, Marcelo J. Kuroda, Jörn E. Schmitz, Xin Dang, Yue Zheng, Michelle Lifton, and Norman L. Letvin
J Immunol 2002 168: 499-504. [Abstract] [Full Text] [PDF]  

Decreased IL-15 May Contribute to Elevated IgE and Acute Inflammation in Atopic Dermatitis

Peck Y. Ong, Qutayba A. Hamid, Jeffrey B. Travers, Ian Strickland, Muhamed Al Kerithy, Mark Boguniewicz, and Donald Y. M. Leung
J Immunol 2002 168: 505-510. [Abstract] [Full Text] [PDF]  

ERRATA:

CORRECTION

J Immunol 2002 168: 511. [Full Text] [PDF]  

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