CUTTING EDGE:

Cutting Edge: The CD45 Tyrosine Phosphatase Is an Inhibitor of Lck Activity in Thymocytes

Ugo D’Oro and Jonathan D. Ashwell
J Immunol 1999 162: 1879-1883. [Abstract] [Full Text] [PDF]  

Cutting Edge: Chronic Intestinal Inflammation in STAT-4 Transgenic Mice: Characterization of Disease and Adoptive Transfer by TNF- Plus IFN--Producing CD4⁺ T Cells That Respond to Bacterial Antigens

Stefan Wirtz, Susetta Finotto, Stephan Kanzler, Ansgar W. Lohse, Manfred Blessing, Hans A. Lehr, Peter R. Galle, and Markus F. Neurath
J Immunol 1999 162: 1884-1888. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Fas Ligand and Fas Are Expressed Constitutively in Human Astrocytes and the Expression Increases with IL-1, IL-6, TNF-, or IFN-

Chulhee Choi, Joo Young Park, Jeonggi Lee, Jung-Hee Lim, Eui-Cheol Shin, Young Soo Ahn, Chul-Hoon Kim, Se-Jong Kim, Joo-Deuk Kim, Il Saing Choi, and In-Hong Choi
J Immunol 1999 162: 1889-1895. [Abstract] [Full Text] [PDF]  

Differential Effects of IL-2 and IL-15 on the Death and Survival of Activated TCR⁺ Intestinal Intraepithelial Lymphocytes

Ching-Liang Chu, Shih-Shun Chen, Tzong-Shoon Wu, Szu-Cheng Kuo, and Nan-Shih Liao
J Immunol 1999 162: 1896-1903. [Abstract] [Full Text] [PDF]  

Mucosally Induced Systemic T Cell Unresponsiveness to Ovalbumin Requires CD40 Ligand-CD40 Interactions

Mi-Na Kweon, Kohtaro Fujihashi, Yoshio Wakatsuki, Toshiya Koga, Masafumi Yamamoto, Jerry R. McGhee, and Hiroshi Kiyono
J Immunol 1999 162: 1904-1909. [Abstract] [Full Text] [PDF]  

Direct Delivery of the Bordetella pertussis Adenylate Cyclase Toxin to the MHC Class I Antigen Presentation Pathway

Pierre Guermonprez, Daniel Ladant, Gouzel Karimova, Agnes Ullmann, and Claude Leclerc
J Immunol 1999 162: 1910-1916. [Abstract] [Full Text] [PDF]  

A Genome-Wide Search Identifies Two Susceptibility Loci for Experimental Autoimmune Encephalomyelitis on Rat Chromosomes 4 and 10

Marie-Paule Roth, Carine Viratelle, Laurence Dolbois, Maxence Delverdier, Nicolas Borot, Lucette Pelletier, Philippe Druet, Michel Clanet, and Hélène Coppin
J Immunol 1999 162: 1917-1922. [Abstract] [Full Text] [PDF]  

TCR-Independent Pathways Mediate the Effects of Antigen Dose and Altered Peptide Ligands on Th Cell Polarization

Arash Grakoui, David L. Donermeyer, Osami Kanagawa, Kenneth M. Murphy, and Paul M. Allen
J Immunol 1999 162: 1923-1930. [Abstract] [Full Text] [PDF]  

Regulation of Cell Survival During B Lymphopoiesis: Apoptosis and Bcl-2/Bax Content of Precursor B Cells in Bone Marrow of Mice with Altered Expression of IL-7 and Recombinase-Activating Gene-2

Liwei Lu, Prosanto Chaudhury, and Dennis G. Osmond
J Immunol 1999 162: 1931-1940. [Abstract] [Full Text] [PDF]  

The p65 Subunit of NF-B Is Redundant with p50 During B Cell Proliferative Responses, and Is Required for Germline C_H Transcription and Class Switching to IgG3

Bruce H. Horwitz, Piotr Zelazowski, Yi Shen, Karen M. Wolcott, Martin L. Scott, David Baltimore, and Clifford M. Snapper
J Immunol 1999 162: 1941-1946. [Abstract] [Full Text] [PDF]  

The Role of CD80, CD86, and CTLA4 in Alloimmune Responses and the Induction of Long-Term Allograft Survival

Thomas A. Judge, Zihou Wu, Xiang-Guang Zheng, Arlene H. Sharpe, Mohamed H. Sayegh, and Laurence A. Turka
J Immunol 1999 162: 1947-1951. [Abstract] [Full Text] [PDF]  

CD38-Mediated Signaling Events in Murine Pro-B Cells Expressing Human CD38 With or Without Its Cytoplasmic Domain

Akira Kitanaka, Toshio Suzuki, Chikako Ito, Hikari Nishigaki, Elaine Coustan-Smith, Terukazu Tanaka, Yoshitsugu Kubota, and Dario Campana
J Immunol 1999 162: 1952-1958. [Abstract] [Full Text] [PDF]  

Lymphotactin Acts as an Innate Mucosal Adjuvant

James W. Lillard, Jr., Prosper N. Boyaka, Joseph A. Hedrick, Albert Zlotnik, and Jerry R. McGhee
J Immunol 1999 162: 1959-1965. [Abstract] [Full Text] [PDF]  

Identification of Tyrosine Phosphorylation Sites in the CD28 Cytoplasmic Domain and Their Role in the Costimulation of Jurkat T Cells

Ali Sadra, Tomas Cinek, Jerry L. Arellano, Jia Shi, Kenneth E. Truitt, and John B. Imboden
J Immunol 1999 162: 1966-1973. [Abstract] [Full Text] [PDF]  

Dose-Dependent Induction of Distinct Anergic Phenotypes: Multiple Levels of T Cell Anergy

Leonie S. Taams, Willem van Eden, and Marca H. M. Wauben
J Immunol 1999 162: 1974-1981. [Abstract] [Full Text] [PDF]  

Use of Antagonist Peptides to Inhibit In Vitro T Cell Responses to Par j1, the Major Allergen of Parietaria judaica Pollen

Raffaele De Palma, Shenhong Wu, Federica Sallusto, Gabriella Di Felice, Paola Martucci, Domenico Geraci, Paolo Colombo, Costantino Troise, Guido Sacerdoti, Arcangelo Nocera, and Jack Gorski
J Immunol 1999 162: 1982-1987. [Abstract] [Full Text] [PDF]  

Fas Ligand Induction in Human NK Cells Is Regulated by Redox Through a Calcineurin-Nuclear Factors of Activated T Cell-Dependent Pathway

Keizo Furuke, Mitsuhiro Shiraishi, Howard S. Mostowski, and Eda T. Bloom
J Immunol 1999 162: 1988-1993. [Abstract] [Full Text] [PDF]  

Intranasally Induced Immunological Tolerance Is Determined by Characteristics of the Draining Lymph Nodes: Studies with OVA and Human Cartilage gp-39

Danielle A. W. Wolvers, Christina J. J. Coenen-de Roo, Reina E. Mebius, Maarten J. F. van der Cammen, Felicia Tirion, André M. M. Miltenburg, and Georg Kraal
J Immunol 1999 162: 1994-1998. [Abstract] [Full Text] [PDF]  

Evidence of Positive Cross-Regulation on Th1 by Th2 and Antigen-Presenting Cells: Effects on Th1 Induced by IL-4 and IL-12

Timothy B. Oriss, Susan A. McCarthy, Martha A. K. Campana, and Penelope A. Morel
J Immunol 1999 162: 1999-2007. [Abstract] [Full Text] [PDF]  

Dual MHC Class I and Class II Restriction of a Single T Cell Receptor: Distinct Modes of Tolerance Induction by Two Classes of Autoantigens

Ivica Arsov and Stanislav Vukmanovic
J Immunol 1999 162: 2008-2015. [Abstract] [Full Text] [PDF]  

Specific CD3 Association of a Phosphodiesterase 4B Isoform Determines Its Selective Tyrosine Phosphorylation After CD3 Ligation

Miren L. Baroja, Lenora B. Cieslinski, Theodore J. Torphy, Ronald L. Wange, and Joaquín Madrenas
J Immunol 1999 162: 2016-2023. [Abstract] [Full Text] [PDF]  

CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion

Joseph R. Maxwell, Jeff D. Campbell, Carol H. Kim, and Anthony T. Vella
J Immunol 1999 162: 2024-2034. [Abstract] [Full Text] [PDF]  

Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells

Thaddeus C. George, Llewellyn H. Mason, John R. Ortaldo, Vinay Kumar, and Michael Bennett
J Immunol 1999 162: 2035-2043. [Abstract] [Full Text] [PDF]  

Human Effector Memory T Cells Express CD86: A Functional Role in Naive T Cell Priming

Pascale Jeannin, Nathalie Herbault, Yves Delneste, Giovanni Magistrelli, Sybille Lecoanet-Henchoz, Gersende Caron, Jean-Pierre Aubry, and Jean-Yves Bonnefoy
J Immunol 1999 162: 2044-2048. [Abstract] [Full Text] [PDF]  

Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax

Edward J. Goetzl, Yvonne Kong, and Baisong Mei
J Immunol 1999 162: 2049-2056. [Abstract] [Full Text] [PDF]  

Calcium-Dependent Activation of TNF Family Gene Expression by Ca²⁺/Calmodulin Kinase Type IV/Gr and Calcineurin

Francis M. Lobo, Reza Zanjani, Nga Ho, Talal A. Chatila, and Ramsay L. Fuleihan
J Immunol 1999 162: 2057-2063. [Abstract] [Full Text] [PDF]  

ß₁ Integrin Cross-Linking Inhibits CD16-Induced Phospholipase D and Secretory Phospholipase A₂ Activity and Granule Exocytosis in Human NK cells: Role of Phospholipase D in CD16-Triggered Degranulation

Michele Milella, Angela Gismondi, Paola Roncaioli, Gabriella Palmieri, Stefania Morrone, Mario Piccoli, Luigi Frati, Maria Grazia Cifone, and Angela Santoni
J Immunol 1999 162: 2064-2072. [Abstract] [Full Text] [PDF]  

Serial TCR Engagement and Down-Modulation by Peptide:MHC Molecule Ligands: Relationship to the Quality of Individual TCR Signaling Events

Yasushi Itoh, Bernhard Hemmer, Roland Martin, and Ronald N. Germain
J Immunol 1999 162: 2073-2080. [Abstract] [Full Text] [PDF]  

IL-2, But Not IL-4 and Other Cytokines, Induces Phosphorylation of a 98-kDa Protein Associated with SHP-2, Phosphatidylinositol 3'-Kinase, and Grb2

Massimo Gadina, Chitra Sudarshan, and John J. O’Shea
J Immunol 1999 162: 2081-2086. [Abstract] [Full Text] [PDF]  

Mitogen-Activated Protein Kinase Activation Through Fc Receptor I and Stem Cell Factor Receptor Is Differentially Regulated by Phosphatidylinositol 3-Kinase and Calcineurin in Mouse Bone Marrow-Derived Mast Cells

Tamotsu Ishizuka, Kosuke Chayama, Katsuyuki Takeda, Eckard Hamelmann, Naohiro Terada, Gordon M. Keller, Gary L. Johnson, and Erwin W. Gelfand
J Immunol 1999 162: 2087-2094. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Immunosuppressive Leflunomide Metabolite (A77 1726) Blocks TNF-Dependent Nuclear Factor-B Activation and Gene Expression

Sunil K. Manna and Bharat B. Aggarwal
J Immunol 1999 162: 2095-2102. [Abstract] [Full Text] [PDF]  

Functional Expression of Receptors for Calcitonin Gene-Related Peptide, Calcitonin, and Vasoactive Intestinal Peptide in the Human Thymus and Thymomas from Myasthenia Gravis Patients

J.-C. Marie, A. Wakkach, A.-M. Coudray, E. Chastre, S. Berrih-Aknin, and C. Gespach
J Immunol 1999 162: 2103-2112. [Abstract] [Full Text] [PDF]  

The Orientation and Nature of the Interaction Between Beef Insulin-Specific TCRs and the Insulin/Class II MHC Complex

Joan E. Wither and Brian Vukusic
J Immunol 1999 162: 2113-2122. [Abstract] [Full Text] [PDF]  

Extensive Junctional Diversity in Ig Light Chain Genes from Early B Cell Progenitors of µMT Mice

Laurent A. Bentolila, Stacy Olson, Aaron Marshall, François Rougeon, Christopher J. Paige, Noëlle Doyen, and Gillian E. Wu
J Immunol 1999 162: 2123-2128. [Abstract] [Full Text] [PDF]  

Functional Characterization of the Somatic Hypermutation Process Leading to Antibody D1.3, a High Affinity Antibody Directed Against Lysozyme

Patrick England, Roland Nageotte, Martial Renard, Anne-Laure Page, and Hugues Bedouelle
J Immunol 1999 162: 2129-2136. [Abstract] [Full Text] [PDF]  

Molecular Mechanisms and Selection Influence the Generation of the Human VJ Repertoire

Nancy L. Farner, Thomas Dörner, and Peter E. Lipsky
J Immunol 1999 162: 2137-2145. [Abstract] [Full Text] [PDF]  

Identification of Residues in the First Domain of Human Fc Receptor Essential for Interaction with IgA

Bruce D. Wines, Mark D. Hulett, Gary P. Jamieson, Halina M. Trist, Joanne M. Spratt, and P. Mark Hogarth
J Immunol 1999 162: 2146-2153. [Abstract] [Full Text] [PDF]  

Increased TNF--Induced Apoptosis in Lymphocytes from Aged Humans: Changes in TNF- Receptor Expression and Activation of Caspases

Sudeepta Aggarwal, Sastry Gollapudi, and Sudhir Gupta
J Immunol 1999 162: 2154-2161. [Abstract] [Full Text] [PDF]  

Position Effects of Variable Region Carbohydrate on the Affinity and In Vivo Behavior of an Anti-(16) Dextran Antibody

M. Josefina Coloma, Ryan K. Trinh, Alexander R. Martinez, and Sherie L. Morrison
J Immunol 1999 162: 2162-2170. [Abstract] [Full Text] [PDF]  

Context-Dependent Immunogenicity of an S206G-Substituted H-2D^b-Restricted Simian Virus 40 Large T Antigen Epitope I Variant

Lawrence M. Mylin
J Immunol 1999 162: 2171-2179. [Abstract] [Full Text] [PDF]  

Molecular Basis of Human Complement C1s Deficiency

Yuichi Endo, Kazuko Kanno, Minoru Takahashi, Ken-ichi Yamaguchi, Yoichi Kohno, and Teizo Fujita
J Immunol 1999 162: 2180-2183. [Abstract] [Full Text] [PDF]  

Two Human Neonatal IgM Antibodies Encoded by Different Variable-Region Genes Bind the Same Linear Peptide: Evidence for a Stereotyped Repertoire of Epitope Recognition

Bradley T. Messmer, James J. Sullivan, Nicholas Chiorazzi, Toby C. Rodman, and David S. Thaler
J Immunol 1999 162: 2184-2192. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Signal Transduction Pathways Involved in the Activation of NF-B, AP-1, and c-fos by Mycoplasma fermentans Membrane Lipoproteins in Macrophages

Georges Rawadi, Josefina Garcia, Brigitte Lemercier, and Sergio Roman-Roman
J Immunol 1999 162: 2193-2203. [Abstract] [Full Text] [PDF]  

Mycobacterium bovis Bacille Calmette-Guérin Enhances Pathogenicity of Simian Immunodeficiency Virus Infection and Accelerates Progression to AIDS in Macaques: A Role of Persistent T cell Activation in AIDS Pathogenesis

Dejiang Zhou, Yun Shen, Laura Chalifoux, David Lee-Parritz, Meredith Simon, Prabhat K. Sehgal, Leiya Zheng, Matilda Halloran, and Zheng W. Chen
J Immunol 1999 162: 2204-2216. [Abstract] [Full Text] [PDF]  

IL-12 Administered During Chlamydia psittaci Lung Infection in Mice Confers Immediate and Long-Term Protection and Reduces Macrophage Inflammatory Protein-2 Level and Neutrophil Infiltration in Lung Tissue

Jin Huang, Ming-Dong Wang, Stephen Lenz, Dongya Gao, and Bernhard Kaltenboeck
J Immunol 1999 162: 2217-2226. [Abstract] [Full Text] [PDF]  

Isolation of High Avidity Melanoma-Reactive CTL from Heterogeneous Populations Using Peptide-MHC Tetramers

Cassian Yee, Peter A. Savage, Peter P. Lee, Mark M. Davis, and Philip D. Greenberg
J Immunol 1999 162: 2227-2234. [Abstract] [Full Text] [PDF]  

Mitogenic Activity of Purified Capsular Polysaccharide A from Bacteroides fragilis: Differential Stimulatory Effect on Mouse and Rat Lymphocytes In Vitro

Jeffery O. Brubaker, Qiao Li, Arthur O. Tzianabos, Dennis L. Kasper, and Robert W. Finberg
J Immunol 1999 162: 2235-2242. [Abstract] [Full Text] [PDF]  

The Role of Actin Microfilaments in the Down-Regulation of the Degranulation Response in RBL-2H3 Mast Cells

Luciano Frigeri and John R. Apgar
J Immunol 1999 162: 2243-2250. [Abstract] [Full Text] [PDF]  

TCR Vaccines Against T Cell Lymphoma: QS-21 and IL-12 Adjuvants Induce a Protective CD8⁺ T Cell Response

Carmen P. Wong, Craig Y. Okada, and Ronald Levy
J Immunol 1999 162: 2251-2258. [Abstract] [Full Text] [PDF]  

IFN--Mediated Control of Coxiella burnetii Survival in Monocytes: The Role of Cell Apoptosis and TNF

Jérôme Dellacasagrande, Christian Capo, Didier Raoult, and Jean-Louis Mege
J Immunol 1999 162: 2259-2265. [Abstract] [Full Text] [PDF]  

Fc Receptor-Mediated Activation of Phospholipase D Regulates Macrophage Phagocytosis of IgG-Opsonized Particles

David J. Kusner, Clifton F. Hall, and Stephen Jackson
J Immunol 1999 162: 2266-2274. [Abstract] [Full Text] [PDF]  

Expression of the Neutrophil Chemokine KC in the Colon of Mice with Enterocolitis and by Intestinal Epithelial Cell Lines: Effects of Flora and Proinflammatory Cytokines

Fei Song, Komei Ito, Tim L. Denning, David Kuninger, John Papaconstantinou, William Gourley, Gary Klimpel, Edward Balish, James Hokanson, and Peter B. Ernst
J Immunol 1999 162: 2275-2280. [Abstract] [Full Text] [PDF]  

The ß-Glucan-Binding Lectin Site of Mouse CR3 (CD11b/CD18) and Its Function in Generating a Primed State of the Receptor That Mediates Cytotoxic Activation in Response to iC3b-Opsonized Target Cells

Yu Xia, Václav Vetvicka, Jun Yan, Margareta Hanikyrová, Tanya Mayadas, and Gordon D. Ross
J Immunol 1999 162: 2281-2290. [Abstract] [Full Text] [PDF]  

Bacterial DNA Containing CpG Motifs Stimulates Lymphocyte-Dependent Protection of Mice Against Lethal Infection with Intracellular Bacteria

Karen L. Elkins, Tonya R. Rhinehart-Jones, Scott Stibitz, Jacqueline S. Conover, and Dennis M. Klinman
J Immunol 1999 162: 2291-2298. [Abstract] [Full Text] [PDF]  

Bacterial Superantigens Induce Down-Modulation of CC Chemokine Responsiveness in Human Monocytes Via an Alternative Chemokine Ligand-Independent Mechanism

Rahbar Rahimpour, Gordon Mitchell, Masud H. Khandaker, Chen Kong, Bhagirath Singh, Luoling Xu, Atsuo Ochi, Ross D. Feldman, J. Geoffrey Pickering, Bruce M. Gill, and David J. Kelvin
J Immunol 1999 162: 2299-2307. [Abstract] [Full Text] [PDF]  

Conserved CTL Epitopes Shared Between HIV-Infected Human Long-Term Survivors and Chimpanzees

Sunita S. Balla-Jhagjhoorsingh, Gerrit Koopman, Petra Mooij, Tom G. M. Haaksma, Vera J. P. Teeuwsen, Ronald E. Bontrop, and Jonathan L. Heeney
J Immunol 1999 162: 2308-2314. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Anti-KS: Identification of Autoantibodies to Asparaginyl-Transfer RNA Synthetase Associated with Interstitial Lung Disease

Michito Hirakata, Akira Suwa, Sonoko Nagai, Michael A. Kron, Edward P. Trieu, Tsuneyo Mimori, Masashi Akizuki, and Ira N. Targoff
J Immunol 1999 162: 2315-2320. [Abstract] [Full Text] [PDF]  

In Vitro and In Vivo Dependency of Chemokine Generation on C5a and TNF-

Boris J. Czermak, Vidya Sarma, Nicolas M. Bless, Hagen Schmal, Hans Peter Friedl, and Peter A. Ward
J Immunol 1999 162: 2321-2325. [Abstract] [Full Text] [PDF]  

CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?

Philippe Saas, José Boucraut, Anne-Lise Quiquerez, Valérie Schnuriger, Gaelle Perrin, Sophie Desplat-Jego, Dominique Bernard, Paul R. Walker, and Pierre-Yves Dietrich
J Immunol 1999 162: 2326-2333. [Abstract] [Full Text] [PDF]  

Phosphorylation of Cytosolic Phospholipase A₂ and the Release of Arachidonic Acid in Human Neutrophils

Sergei I. Syrbu, Waltraut H. Waterman, Thaddeus F. P. Molski, Deepa Nagarkatti, Jean-Jacques Hajjar, and Ramadan I. Sha’afi
J Immunol 1999 162: 2334-2340. [Abstract] [Full Text] [PDF]  

Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis

C. James Cummings, Thomas R. Martin, Charles W. Frevert, Joanne M. Quan, Venus A. Wong, Steven M. Mongovin, Tonja R. Hagen, Kenneth P. Steinberg, and Richard B. Goodman
J Immunol 1999 162: 2341-2346. [Abstract] [Full Text] [PDF]  

Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways

Martti Laan, Zhi-Hua Cui, Hiroshi Hoshino, Jan Lötvall, Margareta Sjöstrand, Dieter C. Gruenert, Bengt-Eric Skoogh, and Anders Lindén
J Immunol 1999 162: 2347-2352. [Abstract] [Full Text] [PDF]  

Anti-ICAM-1 Monoclonal Antibody R6.5 (Enlimomab) Promotes Activation of Neutrophils in Whole Blood

Juha Vuorte, Perttu J. Lindsberg, Markku Kaste, Seppo Meri, Sten-Erik Jansson, Robert Rothlein, and Heikki Repo
J Immunol 1999 162: 2353-2357. [Abstract] [Full Text] [PDF]  

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Inhibit Endotoxin-Induced TNF- Production by Macrophages: In Vitro and In Vivo Studies

Mario Delgado, David Pozo, Carmen Martinez, Javier Leceta, Juan Ramon Calvo, Doina Ganea, and Rosa P. Gomariz
J Immunol 1999 162: 2358-2367. [Abstract] [Full Text] [PDF]  

Immunostimulatory CpG-Oligodeoxynucleotides Cause Extramedullary Murine Hemopoiesis

Tim Sparwasser, Lothar Hültner, Eva Sophie Koch, Arne Luz, Grayson B. Lipford, and Hermann Wagner
J Immunol 1999 162: 2368-2374. [Abstract] [Full Text] [PDF]  

Modulation of Airway Inflammation by Passive Transfer of Allergen-Specific Th1 and Th2 Cells in a Mouse Model of Asthma

David A. Randolph, Cynthia J. L. Carruthers, Susanne J. Szabo, Kenneth M. Murphy, and David D. Chaplin
J Immunol 1999 162: 2375-2383. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Determinant Spreading Associated with Demyelination in a Nonhuman Primate Model of Multiple Sclerosis

Hugh I. McFarland, Adrian A. Lobito, Michele M. Johnson, Jeffrey T. Nyswaner, Joseph A. Frank, Gregory R. Palardy, Nancy Tresser, Claude P. Genain, John P. Mueller, Louis A. Matis, and Michael J. Lenardo
J Immunol 1999 162: 2384-2390. [Abstract] [Full Text] [PDF]  

Cross-Linking of CD44 on Rheumatoid Synovial Cells Up-Regulates VCAM-1

Koichi Fujii, Yoshiya Tanaka, Stefan Hubscher, Kazuyoshi Saito, Toshiyuki Ota, and Sumiya Eto
J Immunol 1999 162: 2391-2398. [Abstract] [Full Text] [PDF]  

IFN- 2B Enhances Th1 Cytokine Responses in Bladder Cancer Patients Receiving Mycobacterium bovis Bacillus Calmette-Guérin Immunotherapy

Yi Luo, Xiaohong Chen, Tracy M. Downs, William C. DeWolf, and Michael A. O’Donnell
J Immunol 1999 162: 2399-2405. [Abstract] [Full Text] [PDF]  

"Allergen Engineering": Variants of the Timothy Grass Pollen Allergen Phl p 5b with Reduced IgE-Binding Capacity but Conserved T Cell Reactivity

Gabriele Schramm, Helga Kahlert, Roland Suck, Bernhard Weber, Hans-Thomas Stüwe, Wolf-Dieter Müller, Albrecht Bufe, Wolf-Meinhard Becker, Max W. Schlaak, Lothar Jäger, Oliver Cromwell, and Helmut Fiebig
J Immunol 1999 162: 2406-2414. [Abstract] [Full Text] [PDF]  

Genetic Dissection of SLE Pathogenesis: Adoptive Transfer of Sle1 Mediates the Loss of Tolerance by Bone Marrow-Derived B Cells

Eric S. Sobel, Chandra Mohan, Laurence Morel, Joel Schiffenbauer, and Edward K. Wakeland
J Immunol 1999 162: 2415-2421. [Abstract] [Full Text] [PDF]  

A Conformation-Dependent Epitope in Addison’s Disease and Other Endocrinological Autoimmune Diseases Maps to a Carboxyl-Terminal Functional Domain of Human Steroid 21-Hydroxylase

Andrej Nikoshkov, Alberto Falorni, Svetlana Lajic, Stefano Laureti, Anna Wedell, Åke Lernmark, and Holger Luthman
J Immunol 1999 162: 2422-2426. [Abstract] [Full Text] [PDF]  

Extracellular HIV-1 Tat Protein Up-Regulates the Expression of Surface CXC-Chemokine Receptor 4 in Resting CD4⁺ T Cells

Paola Secchiero, Davide Zella, Silvano Capitani, Robert C. Gallo, and Giorgio Zauli
J Immunol 1999 162: 2427-2431. [Abstract] [Full Text] [PDF]  

Adjuvanticity of the Cholera Toxin A1-Based Gene Fusion Protein, CTA1-DD, Is Critically Dependent on the ADP-Ribosyltransferase and Ig-Binding Activity

Lena C. Ågren, Lena Ekman, Björn Löwenadler, John G. Nedrud, and Nils Y. Lycke
J Immunol 1999 162: 2432-2440. [Abstract] [Full Text] [PDF]  

Expression of the IL-12 Receptor ß1 and ß2 Subunits in Human Tuberculosis

Ming Zhang, Jianhua Gong, David H. Presky, Wanfen Xue, and Peter F. Barnes
J Immunol 1999 162: 2441-2447. [Abstract] [Full Text] [PDF]  

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