EDITORIALS:

More Changes in The Journal of Immunology

Frank W. Fitch
J Immunol 1998 160: 1. [Full Text] [PDF]  

CUTTING EDGE:

Cutting Edge: Lymphocyte Inhibitor of TRAIL (TNF-Related Apoptosis-Inducing Ligand): A New Receptor Protecting Lymphocytes from the Death Ligand TRAIL

Juthathip Mongkolsapaya, Alison E. Cowper, Xiao-Ning Xu, Gwilym Morris, Andrew J. McMichael, John I. Bell, and Gavin R. Screaton
J Immunol 1998 160: 3-6. [Abstract] [Full Text] [PDF]  

Cutting Edge: p21-Activated Kinase (PAK) Is Required for Fas-Induced JNK Activation in Jurkat Cells

Thomas Rudel, Frank T. Zenke, Tsung-Hsien Chuang, and Gary M. Bokoch
J Immunol 1998 160: 7-11. [Abstract] [Full Text] [PDF]  

Cutting Edge: CTLA-4 Ligation Delivers a Unique Signal to Resting Human CD4 T Cells That Inhibits Interleukin-2 Secretion but Allows Bcl-X_L Induction

Patrick J. Blair, James L. Riley, Bruce L. Levine, Kelvin P. Lee, Nancy Craighead, Tara Francomano, Steven J. Perfetto, Gary S. Gray, Beatriz M. Carreno, and Carl H. June
J Immunol 1998 160: 12-15. [Abstract] [Full Text] [PDF]  

Cutting Edge: Critical Role of NK1⁺ T Cells in IL-12-Induced Immune Responses In Vivo

Toshihiko Kawamura, Kazuyoshi Takeda, Sanjeev K. Mendiratta, Hiroki Kawamura, Luc Van Kaer, Hideo Yagita, Toru Abo, and Ko Okumura
J Immunol 1998 160: 16-19. [Abstract] [Full Text] [PDF]  

Cutting Edge: Identification of the Mouse IgG3 Receptor: Implications for Antibody Effector Function at the Interface Between Innate and Adaptive Immunity

Amanda L. Gavin, Nadine Barnes, Hilde M. Dijstelbloem, and P. Mark Hogarth
J Immunol 1998 160: 20-23. [Abstract] [Full Text] [PDF]  

Cutting Edge: Stimulation of CD28 with B7–2 Promotes Focal Adhesion-Like Cell Contacts Where Rho Family Small G Proteins Accumulate in T Cells

Shuji Kaga, Scott Ragg, Kem A. Rogers, and Atsuo Ochi
J Immunol 1998 160: 24-27. [Abstract] [Full Text] [PDF]  

Cutting Edge: HIV-1 Infection Induces a Selective Reduction in STAT5 Protein Expression

Federica Pericle, Ligia A. Pinto, Stuart Hicks, Robert A. Kirken, Giuseppe Sconocchia, Janice Rusnak, Matthew J. Dolan, Gene M. Shearer, and David M. Segal
J Immunol 1998 160: 28-31. [Abstract] [Full Text] [PDF]  

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION:

Differences Between Responses of Naive and Activated T Cells to Anergy Induction

Robert J. Hayashi, Dennis Y. Loh, Osami Kanagawa, and Fanping Wang
J Immunol 1998 160: 33-38. [Abstract] [Full Text] [PDF]  

An Alternative Translational Reading Frame Encodes an Immunodominant Retroviral CTL Determinant Expressed by an Immunodeficiency-Causing Retrovirus

Shawn-Marie Mayrand, David A. Schwarz, and William R. Green
J Immunol 1998 160: 39-50. [Abstract] [Full Text] [PDF]  

A New Role for B Cells in Systemic Autoimmunity: B Cells Promote Spontaneous T Cell Activation in MRL-lpr/lpr Mice

Owen Chan and Mark J. Shlomchik
J Immunol 1998 160: 51-59. [Abstract] [Full Text] [PDF]  

IL-4 Induces Eotaxin: A Possible Mechanism of Selective Eosinophil Recruitment in Helminth Infection and Atopy

Mitsuru Mochizuki, Joachim Bartels, Antony I. Mallet, Enno Christophers, and Jens-M. Schröder
J Immunol 1998 160: 60-68. [Abstract] [Full Text] [PDF]  

In SCID-hu Mice, Passive Transfer of a Humanized Antibody Prevents Infection and Atrophic Change of Medulla in Human Thymic Implant due to Intravenous Inoculation of Primary HIV-1 Isolate

Yukari Okamoto, Yasuyuki Eda, Atsuo Ogura, Shinwa Shibata, Takashi Amagai, Yoshimoto Katsura, Toshihiko Asano, Kazuhiko Kimachi, Keiichi Makizumi, and Mitsuo Honda
J Immunol 1998 160: 69-76. [Abstract] [Full Text] [PDF]  

Naturally Occurring Low Affinity Peptide/MHC Class I Ligands Can Mediate Negative Selection and T Cell Activation

Bruce Motyka and Hung-Sia Teh
J Immunol 1998 160: 77-86. [Abstract] [Full Text] [PDF]  

Differential Effects of the Rejection of Bone Marrow Allografts by the Depletion of Activating Versus Inhibiting Ly-49 Natural Killer Cell Subsets

Arati Raziuddin, Dan L. Longo, Llewellyn Mason, John R. Ortaldo, Michael Bennett, and William J. Murphy
J Immunol 1998 160: 87-94. [Abstract] [Full Text] [PDF]  

Normal Responsiveness of CTLA-4-Deficient Anti-Viral Cytotoxic T Cells

Martin F. Bachmann, Paul Waterhouse, Daniel E. Speiser, Kim McKall-Faienza, Tak W. Mak, and Pamela S. Ohashi
J Immunol 1998 160: 95-100. [Abstract] [Full Text] [PDF]  

Spontaneous Inflammatory Disease in HLA-B27 Transgenic Mice Is Independent of MHC Class II Molecules: A Direct Role for B27 Heavy Chains and Not B27-Derived Peptides

Sanjay D. Khare, Michael J. Bull, Julie Hanson, Harvinder S. Luthra, and Chella S. David
J Immunol 1998 160: 101-106. [Abstract] [Full Text] [PDF]  

Long-Lived B Cells Are Distinguished by Elevated Expression of A1

Mary M. Tomayko and Michael P. Cancro
J Immunol 1998 160: 107-111. [Abstract] [Full Text] [PDF]  

Post-Thymic Maturation of Migrating Human Thymic Single-Positive T Cells: Thymic CD1a^- CD4⁺ T Cells Are More Susceptible to Anergy Induction by Toxic Shock Syndrome Toxin-1 than Cord Blood CD4⁺ T Cells

Ken’ichi Imanishi, Kazuhiro Seo, Hidehito Kato, Tohru Miyoshi-Akiyama, Rui-Hua Zhang, Yoshinori Takanashi, Yasuharu Imai, and Takehiko Uchiyama
J Immunol 1998 160: 112-119. [Abstract] [Full Text] [PDF]  

TNF Receptor-Deficient Mice Reveal Striking Differences Between Several Models of Thymocyte Negative Selection

Dawne M. Page, Edda M. Roberts, Jacques J. Peschon, and Stephen M. Hedrick
J Immunol 1998 160: 120-133. [Abstract] [Full Text] [PDF]  

The c-Jun N-Terminal Kinase Cascade Plays a Role in Stress-Induced Apoptosis in Jurkat Cells by Up-Regulating Fas Ligand Expression

Mary Faris, Niels Kokot, Kevin Latinis, Shailaja Kasibhatla, Douglas R. Green, Gary A. Koretzky, and Andre Nel
J Immunol 1998 160: 134-144. [Abstract] [Full Text] [PDF]  

Harnessing Syk Family Tyrosine Kinases as Signaling Domains for Chimeric Single Chain of the Variable Domain Receptors: Optimal Design for T Cell Activation

Cheryl J. Fitzer-Attas, Daniel G. Schindler, Tova Waks, and Zelig Eshhar
J Immunol 1998 160: 145-154. [Abstract] [Full Text] [PDF]  

Induction of Granulomatous Experimental Autoimmune Thyroiditis in IL-4 Gene-Disrupted Mice

Haiwen Tang, Gordon C. Sharp, Karin E. Peterson, and Helen Braley-Mullen
J Immunol 1998 160: 155-162. [Abstract] [Full Text] [PDF]  

Regulation of TCR Signal Transduction in Murine Thymocytes by Multiple TCR -Chain Signaling Motifs

Nicolai S. C. van Oers, Paul E. Love, Elizabeth W. Shores, and Arthur Weiss
J Immunol 1998 160: 163-170. [Abstract] [Full Text] [PDF]  

MOLECULAR AND STRUCTURAL IMMUNOLOGY:

Reduced Cell Surface Expression of HLA-C Molecules Correlates with Restricted Peptide Binding and Stable TAP Interaction

Anne Neisig, Cornelis J. M. Melief, and Jacques Neefjes
J Immunol 1998 160: 171-179. [Abstract] [Full Text] [PDF]  

Detection and Delineation of CXCR-4 (Fusin) as an Entry and Fusion Cofactor for T Cell-Tropic HIV-1 by Three Different Monoclonal Antibodies

Toshiyuki Hori, Hitoshi Sakaida, Akihiko Sato, Toshihiro Nakajima, Hisatoshi Shida, Osamu Yoshie, and Takashi Uchiyama
J Immunol 1998 160: 180-188. [Abstract] [Full Text] [PDF]  

The MHC-E Locus Is the Most Well Conserved of All Known Primate Class I Histocompatibility Genes

Leslie A. Knapp, Luis F. Cadavid, and David I. Watkins
J Immunol 1998 160: 189-196. [Abstract] [Full Text] [PDF]  

Characterization and Mapping to Human Chromosome 8q24.3 of Ly-6-Related Gene 9804 Encoding an Apparent Homologue of Mouse TSA-1

Xiaochuan Shan, Annie Bourdeau, Angela Rhoton, Dan E. Wells, Edward H. Cohen, Bryan E. Landgraf, and Roger G. E. Palfree
J Immunol 1998 160: 197-208. [Abstract] [Full Text] [PDF]  

Nuclear Factor of Activated T Cells (NFAT) as a Molecular Target for 1,25-Dihydroxyvitamin D₃-Mediated Effects

Atsuko Takeuchi, G. Satyanarayana Reddy, Tadashi Kobayashi, Toshio Okano, Jungchan Park, and Surendra Sharma
J Immunol 1998 160: 209-218. [Abstract] [Full Text] [PDF]  

Identification of an Inhibitory MHC Receptor on Alloreactive Rat Natural Killer Cells

Christian Naper, James C. Ryan, Mary C. Nakamura, Doris Lambracht, Bent Rolstad, and John T. Vaage
J Immunol 1998 160: 219-224. [Abstract] [Full Text] [PDF]  

Staphylococcal Enterotoxin D Is a Promiscuous Superantigen Offering Multiple Modes of Interactions With the MHC Class II Receptors

Reem Al-Daccak, Khalil Mehindate, Farida Damdoumi, Pierre Etongué-Mayer, Helen Nilsson, Per Antonsson, Michael Sundström, Mikael Dohlsten, Rafick-Pierre Sékaly, and Walid Mourad
J Immunol 1998 160: 225-232. [Abstract] [Full Text] [PDF]  

Identification of Distinct Regions of 5' Flanking DNA That Mediate Constitutive, IFN-, STAT1, and TGF-ß-Regulated Expression of the Class II Transactivator Gene

Janet F. Piskurich, Ying Wang, Michael W. Linhoff, Leigh C. White, and Jenny P.-Y. Ting
J Immunol 1998 160: 233-240. [Abstract] [Full Text] [PDF]  

A Two-Step Mechanism for Recruitment of Pip by PU.1

Jeffrey M. Perkel and Michael L. Atchison
J Immunol 1998 160: 241-252. [Abstract] [Full Text] [PDF]  

Monoclonal Anti-Cardiolipin Antibodies from New Zealand Black x New Zealand White F₁ Mice React to Thrombomodulin

Kazuhiko Haruta, Shigeto Kobayashi, Sachiko Hirose, Aiko Horiai, Mutsuko Ohyanagi, Mitsuhiko Tanaka, Terunaga Kawano, Toshikazu Shirai, Yoshinari Takasaki, and Hiroshi Hashimoto
J Immunol 1998 160: 253-258. [Abstract] [Full Text] [PDF]  

V_H Repertoire of a Marsupial (Monodelphis domestica)

Robert D. Miller, Hilary Grabe, and George H. Rosenberg
J Immunol 1998 160: 259-265. [Abstract] [Full Text] [PDF]  

Molecular Analysis of the Major MHC Recombinational Hot Spot Located Within the G7c Gene of the Murine Class III Region That Is Involved in Disease Susceptibility

Margriet Snoek, Cory Teuscher, and Huub van Vugt
J Immunol 1998 160: 266-272. [Abstract] [Full Text] [PDF]  

HOST DEFENSE:

Common and Distinct Signaling Pathways Mediate the Induction of TNF- and IL-5 in IgE Plus Antigen-Stimulated Mast Cells

R. Csonga, E. E. Prieschl, D. Jaksche, V. Novotny, and T. Baumruker
J Immunol 1998 160: 273-283. [Abstract] [Full Text] [PDF]  

The Role of Recombinant Murine IL-12 and IFN- in the Pathogenesis of a Murine Systemic Candida albicans Infection

Liz M. Lavigne, Lisa R. Schopf, Charles L. Chung, Rich Maylor, and Joseph P. Sypek
J Immunol 1998 160: 284-292. [Abstract] [Full Text] [PDF]  

Peptides That Mimic the Group B Streptococcal Type III Capsular Polysaccharide Antigen

Seth H. Pincus, Michael J. Smith, Harold J. Jennings, James B. Burritt, and Pati M. Glee
J Immunol 1998 160: 293-298. [Abstract] [Full Text] [PDF]  

IL-18 (IFN--Inducing Factor) Regulates Early Cytokine Production in, and Promotes Resolution of, Bacterial Infection in Mice

Erwin Bohn, Andreas Sing, Robert Zumbihl, Claudia Bielfeldt, Haruki Okamura, Masashi Kurimoto, Jürgen Heesemann, and Ingo B. Autenrieth
J Immunol 1998 160: 299-307. [Abstract] [Full Text] [PDF]  

Septic Arthritis Following Staphylococcus aureus Infection in Mice Lacking Inducible Nitric Oxide Synthase

Iain B. McInnes, Bernard Leung, Xiao-Qing Wei, Curtis C. Gemmell, and Foo Y. Liew
J Immunol 1998 160: 308-315. [Abstract] [Full Text] [PDF]  

Legionella pneumophila Infection in Intratracheally Inoculated T Cell-Depleted or -Nondepleted A/J Mice

Milorad Susa, Brigita Ticac, Tomislav Rukavina, Miljenko Doric, and Reinhard Marre
J Immunol 1998 160: 316-321. [Abstract] [Full Text] [PDF]  

Mechanism of Protective Immunity Against Influenza Virus Infection in Mice Without Antibodies

Suzanne L. Epstein, Chia-Yun Lo, Julia A. Misplon, and Jack R. Bennink
J Immunol 1998 160: 322-327. [Abstract] [Full Text] [PDF]  

Accumulation of the p53 Protein Allows Recognition by Human CTL of a Wild-Type p53 Epitope Presented by Breast Carcinomas and Melanomas

Sacha Gnjatic, Zhenzi Cai, Mireille Viguier, Salem Chouaib, Jean-Gérard Guillet, and Jeannine Choppin
J Immunol 1998 160: 328-333. [Abstract] [Full Text] [PDF]  

Successful Adoptive Cellular Immunotherapy Is Dependent on Induction of a Host Immune Response Triggered by Cytokine (IFN- and Granulocyte/Macrophage Colony-Stimulating Factor) Producing Donor Tumor-Infiltrating Lymphocytes

Makoto Nagoshi, Peter S. Goedegebuure, Ulrike L. Burger, Noriaki Sadanaga, Maximilian P. Chang, and Timothy J. Eberlein
J Immunol 1998 160: 334-344. [Abstract] [Full Text] [PDF]  

Neutrophils but Not Eosinophils Are Involved in Growth Suppression of IL-4-Secreting Tumors

Gabriele Noffz, Zhihai Qin, Manfred Kopf, and Thomas Blankenstein
J Immunol 1998 160: 345-350. [Abstract] [Full Text] [PDF]  

Helminth Antigens Selectively Differentiate Unsensitized CD45RA⁺CD4⁺ Human T Cells in Vitro

Cathy Steel and Thomas B. Nutman
J Immunol 1998 160: 351-360. [Abstract] [Full Text] [PDF]  

Macrophages Kill T9 Glioma Tumor Cells Bearing the Membrane Isoform of Macrophage Colony Stimulating Factor Through a Phagocytosis-Dependent Pathway

Martin R. Jadus, Christopher C. Williams, Maria D. Avina, Mann Ly, Suzanna Kim, Ying Liu, Ryan Narasaki, Clifford A. Lowell, and H. Terry Wepsic
J Immunol 1998 160: 361-368. [Abstract] [Full Text] [PDF]  

Accommodation and T-Independent B Cell Tolerance in Rats With Long Term Surviving Hamster Heart Xenografts

Yuan Lin, Michel Vandeputte, and Mark Waer
J Immunol 1998 160: 369-375. [Abstract] [Full Text] [PDF]  

Chronic Listeria Infection in SCID Mice: Requirements for the Carrier State and the Dual Role of T Cells in Transferring Protection or Suppression

Vatsala Bhardwaj, Osami Kanagawa, Paul E. Swanson, and Emil R. Unanue
J Immunol 1998 160: 376-384. [Abstract] [Full Text] [PDF]  

Lymphoid Hyperplasia, Autoimmunity, and Compromised Intestinal Intraepithelial Lymphocyte Development in Colitis-Free Gnotobiotic IL-2-Deficient Mice

Nikhat V. Contractor, Hamid Bassiri, Tannishtha Reya, Audrey Y. Park, Daniel C. Baumgart, Mariusz A. Wasik, Stephen G. Emerson, and Simon R. Carding
J Immunol 1998 160: 385-394. [Abstract] [Full Text] [PDF]  

INFLAMMATION:

Human CD38 (ADP-Ribosyl Cyclase) Is a Counter-Receptor of CD31, an Ig Superfamily Member

Silvia Deaglio, Massimo Morra, Roberto Mallone, Clara M. Ausiello, Elisabeth Prager, Giovanni Garbarino, Umberto Dianzani, Hannes Stockinger, and Fabio Malavasi
J Immunol 1998 160: 395-402. [Abstract] [Full Text] [PDF]  

IL-1 and TNF Antagonists Inhibit the Inflammatory Response and Bone Loss in Experimental Periodontitis

R. Assuma, T. Oates, D. Cochran, S. Amar, and D. T. Graves
J Immunol 1998 160: 403-409. [Abstract] [Full Text] [PDF]  

Inhibition of Proinflammatory Molecule Production by Adenovirus-Mediated Expression of a Nuclear Factor B Super-Repressor in Human Intestinal Epithelial Cells

Christian Jobin, Asit Panja, Claus Hellerbrand, Yuji Iimuro, Joseph Didonato, David A. Brenner, and R. Balfour Sartor
J Immunol 1998 160: 410-418. [Abstract] [Full Text] [PDF]  

Regulated Production of Type I Collagen and Inflammatory Cytokines by Peripheral Blood Fibrocytes

Jason Chesney, Christine Metz, Abram B. Stavitsky, Michael Bacher, and Richard Bucala
J Immunol 1998 160: 419-425. [Abstract] [Full Text]  

RANTES-Induced T Cell Activation Correlates with CD3 Expression

Daniel J. Dairaghi, Kenneth S. Soo, Elizabeth R. Oldham, Brett A. Premack, Toshio Kitamura, Kevin B. Bacon, and Thomas J. Schall
J Immunol 1998 160: 426-433. [Abstract] [Full Text] [PDF]  

Importance of MEK in Neutrophil Microbicidal Responsiveness

Gregory P. Downey, Jeffrey R. Butler, Hans Tapper, Lea Fialkow, Alan R. Saltiel, Barry B. Rubin, and Sergio Grinstein
J Immunol 1998 160: 434-443. [Abstract] [Full Text] [PDF]  

CD8⁺ Myelin Peptide-Specific T Cells Can Chemoattract CD4⁺ Myelin Peptide-Specific T Cells: Importance of IFN-Inducible Protein 10

William E. Biddison, William W. Cruikshank, David M. Center, Clara M. Pelfrey, Dennis D. Taub, and Richard V. Turner
J Immunol 1998 160: 444-448. [Abstract] [Full Text] [PDF]  

Regulation of Chemokine Gene Expression in Human Peripheral Blood Neutrophils Phagocytosing Microbial Pathogens

Mohamed Hachicha, Palaniswami Rathanaswami, Paul H. Naccache, and Shaun R. McColl
J Immunol 1998 160: 449-454. [Abstract] [Full Text] [PDF]  

Apical Secretion of a Pathogen-Elicited Epithelial Chemoattractant Activity in Response to Surface Colonization of Intestinal Epithelia by Salmonella typhimurium

Beth A. McCormick, Charles A. Parkos, Sean P. Colgan, Denice K. Carnes, and James L. Madara
J Immunol 1998 160: 455-466. [Abstract] [Full Text] [PDF]  

Adhesion Molecule Mechanisms Mediating Monocyte Migration Through Synovial Fibroblast and Endothelium Barriers: Role for CD11/CD18, Very Late Antigen-4 (CD49d/CD29), Very Late Antigen-5 (CD49e/CD29), and Vascular Cell Adhesion Molecule-1 (CD106)

Xiao-zhou Shang, Bianca J. Lang, and Andrew C. Issekutz
J Immunol 1998 160: 467-474. [Abstract] [Full Text] [PDF]  

Effect of C1 Inhibitor on Inflammatory and Physiologic Response Patterns in Primates Suffering from Lethal Septic Shock

Patty M. Jansen, Bernd Eisele, Irma W. de Jong, Alvin Chang, Ulrich Delvos, Fletcher B. Taylor, Jr., and C. Erik Hack
J Immunol 1998 160: 475-484. [Abstract] [Full Text] [PDF]  

Differential Activities of Secreted Lymphotoxin-₃ and Membrane Lymphotoxin-₁ß₂ in Lymphotoxin-Induced Inflammation: Critical Role of TNF Receptor 1 Signaling

Rosalba Sacca, Carolyn A. Cuff, Werner Lesslauer, and Nancy H. Ruddle
J Immunol 1998 160: 485-491. [Abstract] [Full Text] [PDF]  

CLINICAL IMMUNOLOGY:

Distinct Classes of Chaperoned IL-6 in Human Blood: Differential Immunological and Biological Availability

MacKevin I. Ndubuisi, Kirit Patel, Ravi J. Rayanade, Abraham Mittelman, Lester T. May, and Pravin B. Sehgal
J Immunol 1998 160: 494-501. [Abstract] [Full Text] [PDF]  

A Model of Peptide-Induced Lupus Autoimmune B Cell Epitope Spreading Is Strain Specific and Is Not H-2 Restricted in Mice

Judith A. James and John B. Harley
J Immunol 1998 160: 502-508. [Abstract] [Full Text] [PDF]  

CDR3 Size Spectratyping and Sequencing of Spectratype-Derived TCR of Spinal Cord T Cells in Autoimmune Encephalomyelitis

Giok Kim, Naoyuki Tanuma, Takashi Kojima, Kuniko Kohyama, Yoko Suzuki, Yoko Kawazoe, and Yoh Matsumoto
J Immunol 1998 160: 509-513. [Abstract] [Full Text] [PDF]  

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