EDITORIALS:

The Journal of Immunology is Dead! Long Live the Journal of Immunology!

FW Fitch,
J Immunol 1997 159: 1. [PDF]  

CUTTING EDGE:

Testosterone therapy ameliorates experimental autoimmune encephalomyelitis and induces a T helper 2 bias in the autoantigen- specific T lymphocyte response

M Dalal, S Kim, and RR Voskuhl
J Immunol 1997 159: 3-6. [Abstract] [PDF]  

IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis

IE Flesch, A Wandersee, and SH Kaufmann
J Immunol 1997 159: 7-10. [Abstract] [PDF]  

The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites

A Iwasaki, CA Torres, PS Ohashi, HL Robinson, and BH Barber
J Immunol 1997 159: 11-14. [Abstract] [PDF]  

ARTICLES:

Ca2+-dependent, Fas- and perforin-independent apoptotic death of allografted tumor cells by a type of activated macrophage

R Yoshida, A Sanchez-Bueno, N Yamamoto, and K Einaga-Naito
J Immunol 1997 159: 15-21. [Abstract] [PDF]  

The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms

RT Elder, X Xu, JW Williams, H Gong, A Finnegan, and AS Chong
J Immunol 1997 159: 22-27. [Abstract] [PDF]  

IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells

P Kalinski, CM Hilkens, A Snijders, FG Snijdewint, and ML Kapsenberg
J Immunol 1997 159: 28-35. [Abstract] [PDF]  

Differential expression of transcription directed by a discrete NF-AT binding element from the IL-4 promoter in naive and effector CD4 T cells

TM Aune and RA Flavell
J Immunol 1997 159: 36-43. [Abstract] [PDF]  

Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora

SL Brandwein, RP McCabe, Y Cong, KB Waites, BU Ridwan, PA Dean, T Ohkusa, EH Birkenmeier, JP Sundberg, and CO Elson
J Immunol 1997 159: 44-52. [Abstract] [PDF]  

Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities

A Faith, CA Akdis, M Akdis, HU Simon, and K Blaser
J Immunol 1997 159: 53-60. [Abstract] [PDF]  

Inactivation of lck and loss of TCR-mediated signaling upon persistent engagement with complexes of peptide:MHC molecules

JE Lee, MB Cossoy, LA Chau, B Singh, and J Madrenas
J Immunol 1997 159: 61-69. [Abstract] [PDF]  

Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells

LE Marengere, C Mirtsos, I Kozieradzki, A Veillette, TW Mak, and JM Penninger
J Immunol 1997 159: 70-76. [Abstract] [PDF]  

Immunodominant CD4+ T cell receptor Vbeta repertoires involved in graft- versus-host disease responses to minor histocompatibility antigens

MA Berger and R Korngold
J Immunol 1997 159: 77-85. [Abstract] [PDF]  

Selective expansion of Vgamma2-Vdelta7 TCR gammadelta cells in C57BL/6 mice is postnatal and extrathymic

AI Sperling, DC Decker, RJ DiPaolo, DA Stern, A Shum, and JA Bluestone
J Immunol 1997 159: 86-91. [Abstract] [PDF]  

Regulation of tumor antigen presentation by urocanic acid

S Beissert, T Mohammad, H Torri, A Lonati, Z Yan, H Morrison, and RD Granstein
J Immunol 1997 159: 92-96. [Abstract] [PDF]  

Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type I T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells

K Matsui, T Yoshimoto, H Tsutsui, Y Hyodo, N Hayashi, K Hiroishi, N Kawada, H Okamura, K Nakanishi, and K Higashino
J Immunol 1997 159: 97-106. [Abstract] [PDF]  

Inhibition of primary and recall allergen-specific T helper cell type 2- mediated responses by a T helper cell type 1 stimulus

DE Scott, I Agranovich, J Inman, M Gober, and B Golding
J Immunol 1997 159: 107-116. [Abstract] [PDF]  

TGF-beta down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors

J Tang, BL Nuccie, I Ritterman, JL Liesveld, CN Abboud, and DH Ryan
J Immunol 1997 159: 117-125. [Abstract] [PDF]  

Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis

C Renvoize, R Roger, N Moulian, J Bertoglio, and J Breard
J Immunol 1997 159: 126-134. [Abstract] [PDF]  

xid affects events leading to B cell cycle entry

K Brorson, M Brunswick, S Ezhevsky, DG Wei, R Berg, D Scott, and KE Stein
J Immunol 1997 159: 135-143. [Abstract] [PDF]  

Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression

E Chuang, ML Alegre, CS Duckett, PJ Noel, MG Vander Heiden, and CB Thompson
J Immunol 1997 159: 144-151. [Abstract] [PDF]  

Direct MHC class I complementary DNA transfer to thymus induces donor- specific unresponsiveness, which involves multiple immunologic mechanisms

SJ Knechtle, J Wang, C Graeb, Y Zhai, X Hong, JH Fechner, Jr, and EK Geissler
J Immunol 1997 159: 152-158. [Abstract] [PDF]  

Requirement of CD4 T cells for skin graft rejection against thymus leukemia (TL) antigen and multiple epitopes on the TL molecule recognized by CD4 T cells

K Tsuji, Y Obata, T Takahashi, J Arata, and E Nakayama
J Immunol 1997 159: 159-166. [Abstract] [PDF]  

In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice

X Xu, L Blinder, J Shen, H Gong, A Finnegan, JW Williams, and AS Chong
J Immunol 1997 159: 167-174. [Abstract] [PDF]  

TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes

JJ Bright, LD Kerr, and S Sriram
J Immunol 1997 159: 175-183. [Abstract] [PDF]  

CD38 ligation in human B cell progenitors triggers tyrosine phosphorylation of CD19 and association of CD19 with lyn and phosphatidylinositol 3-kinase

A Kitanaka, C Ito, E Coustan-Smith, and D Campana
J Immunol 1997 159: 184-192. [Abstract] [PDF]  

CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-zeta/zeta-associated protein-70 signaling pathways in Jurkat T lymphocytes

M Zubiaur, M Izquierdo, C Terhorst, F Malavasi, and J Sancho
J Immunol 1997 159: 193-205. [Abstract] [PDF]  

Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones

F Novelli, MM D'Elios, P Bernabei, L Ozmen, L Rigamonti, F Almerigogna, G Forni, and G Del Prete
J Immunol 1997 159: 206-213. [Abstract] [PDF]  

Antigen specificity of dual reactive T hybridomas determines the requirement for CD40 ligand-CD40 interactions

ME Ozaki, L Karlsson, PA Peterson, and SR Webb
J Immunol 1997 159: 214-221. [Abstract] [PDF]  

Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain

E Shores, V Flamand, T Tran, A Grinberg, JP Kinet, and PE Love
J Immunol 1997 159: 222-230. [Abstract] [PDF]  

B cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activation

BJ Vilen, SJ Famiglietti, AM Carbone, BK Kay, and JC Cambier
J Immunol 1997 159: 231-243. [Abstract] [PDF]  

Structural requirements for assembly of dimeric IgA probed by site- directed mutagenesis of J chain and a cysteine residue of the alpha- chain CH2 domain

S Krugmann, RJ Pleass, JD Atkin, and JM Woof
J Immunol 1997 159: 244-249. [Abstract] [PDF]  

Structure and genomic organization of a second class of immunoglobulin light chain genes in the channel catfish

SH Ghaffari and CJ Lobb
J Immunol 1997 159: 250-258. [Abstract] [PDF]  

Isolation and characterization of 2'-fluoro-, 2'-amino-, and 2'-fluoro- /amino-modified RNA ligands to human IFN-gamma that inhibit receptor binding

MF Kubik, C Bell, T Fitzwater, SR Watson, and DM Tasset
J Immunol 1997 159: 259-267. [Abstract] [PDF]  

The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1

CF Lu and TA Springer
J Immunol 1997 159: 268-278. [Abstract] [PDF]  

Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope

RR Garrity, G Rimmelzwaan, A Minassian, WP Tsai, G Lin, JJ de Jong, J Goudsmit, and PL Nara
J Immunol 1997 159: 279-289. [Abstract] [PDF]  

Human alveolar T lymphocyte responses to Mycobacterium tuberculosis antigens: role for CD4+ and CD8+ cytotoxic T cells and relative resistance of alveolar macrophages to lysis

JS Tan, DH Canaday, WH Boom, KN Balaji, SK Schwander, and EA Rich
J Immunol 1997 159: 290-297. [Abstract] [PDF]  

Production of IL-18 (IFN-gamma-inducing factor) messenger RNA and functional protein by murine keratinocytes

S Stoll, G Muller, M Kurimoto, J Saloga, T Tanimoto, H Yamauchi, H Okamura, J Knop, and AH Enk
J Immunol 1997 159: 298-302. [Abstract] [PDF]  

The intronic region of an incompletely spliced gp100 gene transcript encodes an epitope recognized by melanoma-reactive tumor-infiltrating lymphocytes

PF Robbins, M El-Gamil, YF Li, EB Fitzgerald, Y Kawakami, and SA Rosenberg
J Immunol 1997 159: 303-308. [Abstract] [PDF]  

NKR-P1A stimulation of arachidonate-generating enzymes in rat NK cells is associated with granule release and cytotoxic activity

M Grazia Cifone, P Roncaioli, L Cironi, C Festuccia, A Meccia, S D'Alo, D Botti, and A Santoni
J Immunol 1997 159: 309-317. [Abstract] [PDF]  

Macrophage inflammatory protein-1alpha (MIP-1alpha) is required for the efferent phase of pulmonary cell-mediated immunity to a Cryptococcus neoformans infection

GB Huffnagle, RM Strieter, LK McNeil, RA McDonald, MD Burdick, SL Kunkel, and GB Toews
J Immunol 1997 159: 318-327. [Abstract] [PDF]  

IL-12 treatment attenuates T helper cell type 2 and B cell responses but does not improve vaccine-enhanced lung illness

T Hussell, U Khan, and P Openshaw
J Immunol 1997 159: 328-334. [Abstract] [PDF]  

Determinants of T cell reactivity to the Mycobacterium leprae GroES homologue

J Kim, A Sette, S Rodda, S Southwood, PA Sieling, V Mehra, JD Ohmen, J Oliveros, E Appella, Y Higashimoto, TH Rea, BR Bloom, and RL Modlin
J Immunol 1997 159: 335-343. [Abstract] [PDF]  

Differential CD45 isoform expression accompanies reduced natural antibody binding in L5178Y-F9 tumor progression

ZY Zhang and DA Chow
J Immunol 1997 159: 344-350. [Abstract] [PDF]  

Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 subunit homodimer

L Chen, D Chen, E Block, M O'Donnell, DW Kufe, and SK Clinton
J Immunol 1997 159: 351-359. [Abstract] [PDF]  

A mechanism for selective recruitment of CD8 T cells into B7-1- transfected plasmacytoma: role of macrophage-inflammatory protein 1alpha

M Maric, L Chen, B Sherry, and Y Liu
J Immunol 1997 159: 360-368. [Abstract] [PDF]  

Expression of a biologically active recombinant mouse IL-1 receptor antagonist and its use in vivo to modulate aspects of the acute phase response

S Grehan, CM Uhlar, RB Sim, J Herbert, and AS Whitehead
J Immunol 1997 159: 369-378. [Abstract] [PDF]  

IL-13 inhibits TNF production but potentiates that of IL-6 in vivo and ex vivo in mice

E Di Santo, C Meazza, M Sironi, P Fruscella, A Mantovani, JD Sipe, and P Ghezzi
J Immunol 1997 159: 379-382. [Abstract] [PDF]  

Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin

VC Ridger, ER Pettipher, CE Bryant, and SD Brain
J Immunol 1997 159: 383-390. [Abstract] [PDF]  

Endotoxin induces expression of type II phospholipase A2 in macrophages during acute lung injury in guinea pigs: involvement of TNF-alpha in lipopolysaccharide-induced type II phospholipase A2 synthesis

L Arbibe, D Vial, I Rosinski-Chupin, N Havet, M Huerre, BB Vargaftig, and L Touqui
J Immunol 1997 159: 391-400. [Abstract] [PDF]  

Transgenic monocyte chemoattractant protein-1 (MCP-1) in pancreatic islets produces monocyte-rich insulitis without diabetes: abrogation by a second transgene expressing systemic MCP-1

IS Grewal, BJ Rutledge, JA Fiorillo, L Gu, RP Gladue, RA Flavell, and BJ Rollins
J Immunol 1997 159: 401-408. [Abstract] [PDF]  

Fc receptor-triggered insertion of secretory granules into the plasma membrane of human neutrophils: selective retrieval during phagocytosis

H Tapper and S Grinstein
J Immunol 1997 159: 409-418. [Abstract] [PDF]  

Differential regulation of indoleamine 2,3-dioxygenase expression by nitric oxide and inflammatory mediators in IFN-gamma-activated murine macrophages and microglial cells

D Alberati-Giani, P Malherbe, P Ricciardi-Castagnoli, C Kohler, S Denis- Donini, and AM Cesura
J Immunol 1997 159: 419-426. [Abstract] [PDF]  

Shared TCR Vbeta gene expression by the pancreas and salivary gland in immunodeficient alymphoplasic mice

M Yamamichi, N Matsuoka, T Tomioka, K Eguchi, S Nagataki, and T Kanematsu
J Immunol 1997 159: 427-432. [Abstract] [PDF]  

Outside-in signaling by lipopolysaccharide through a tailless integrin

RR Ingalls, MA Arnaout, and DT Golenbock
J Immunol 1997 159: 433-438. [Abstract] [PDF]  

Cyclooxygenase-2-dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells: its augmentation by extracellular type II secretory phospholipase A2

M Murakami, K Tada, K Nakajima, and I Kudo
J Immunol 1997 159: 439-446. [Abstract] [PDF]  

Recombinant histamine-releasing factor enhances IgE-dependent IL-4 and IL-13 secretion by human basophils

JT Schroeder, LM Lichtenstein, and SM MacDonald
J Immunol 1997 159: 447-452. [Abstract] [PDF]  

Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity

C Mohan, L Morel, P Yang, and EK Wakeland
J Immunol 1997 159: 454-465. [Abstract] [PDF]  

Role of macrophages and macrophage-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes in diabetes-resistant BioBreeding rats

YH Chung, HS Jun, Y Kang, K Hirasawa, BR Lee, N Van Rooijen, and JW Yoon
J Immunol 1997 159: 466-471. [Abstract] [PDF]  

Identification of rat prostatic steroid-binding protein as a target antigen of experimental autoimmune prostatitis: implications for prostate cancer therapy

KJ Liu, GS Chatta, DR Twardzik, TS Vedvick, LD True, AG Spies, and MA Cheever
J Immunol 1997 159: 472-480. [Abstract] [PDF]  

Clonal expansion of CD8+ T cells in Kawasaki disease

IH Choi, YJ Chwae, WS Shim, DS Kim, DH Kwon, JD Kim, and SJ Kim
J Immunol 1997 159: 481-486. [Abstract] [PDF]  

A role for insulin-like growth factor in the regulation of IL-6- responsive human myeloma cell line growth

DF Jelinek, TE Witzig, and BK Arendt
J Immunol 1997 159: 487-496. [Abstract] [PDF]  

Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis

T Brabb, AW Goldrath, P von Dassow, A Paez, HD Liggitt, and J Goverman
J Immunol 1997 159: 497-507. [Abstract] [PDF]  

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