CUTTING EDGE:

CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system

SJ Khoury, E Akalin, A Chandraker, LA Turka, PS Linsley, MH Sayegh, and WW Hancock
J Immunol 1995 155: 4521-4524. [Abstract] [PDF]  

Functional glucocorticoid receptor expression is required for cAMP- mediated apoptosis in a human leukemic T cell line

J Kiefer, S Okret, M Jondal, and DJ McConkey
J Immunol 1995 155: 4525-4528. [Abstract] [PDF]  

Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases

VP Poltoratsky, X Shi, JD York, MR Lieber, and TH Carter
J Immunol 1995 155: 4529-4533. [Abstract] [PDF]  

ARTICLES:

Cyclic AMP signaling pathways are important in IL-1 beta transcriptional regulation

G Chandra, JP Cogswell, LR Miller, MM Godlevski, SW Stinnett, SL Noel, SH Kadwell, TA Kost, and JG Gray
J Immunol 1995 155: 4535-4543. [Abstract] [PDF]  

MHC class I-selected CD4-CD8-TCR-alpha beta+ T cells are a potential source of IL-4 during primary immune response

MC Leite-de-Moraes, A Herbelin, F Machavoine, A Vicari, JM Gombert, M Papiernik, and M Dy
J Immunol 1995 155: 4544-4550. [Abstract] [PDF]  

Role of environmental antigen in the development of IgG+ cells in the bursa of fabricius

S Ekino, B Riwar, FG Kroese, EH Schwander, G Koch, and P Nieuwenhuis
J Immunol 1995 155: 4551-4558. [Abstract] [PDF]  

Disturbed MHC regulation in the IFN-gamma knockout mouse. Evidence for three states of MHC expression with distinct roles for IFN-gamma

N Goes, T Sims, J Urmson, D Vincent, V Ramassar, and PF Halloran
J Immunol 1995 155: 4559-4566. [Abstract] [PDF]  

Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes

MJ Halvorson and JE Coligan
J Immunol 1995 155: 4567-4574. [Abstract] [PDF]  

Analysis of thymic subpopulations expressing the activation antigen GL7. Expression, genetics, and function

KS Hathcock, CE Pucillo, G Laszlo, L Lai, and RJ Hodes
J Immunol 1995 155: 4575-4581. [Abstract] [PDF]  

Activation of the signal transducer and transcription (STAT) signaling pathway in a primary T cell response. Critical role for IL-6

T Henttinen, DE Levy, O Silvennoinen, and M Hurme
J Immunol 1995 155: 4582-4587. [Abstract] [PDF]  

CD40 function in nonhematopoietic cells. Nuclear factor kappa B mobilization and induction of IL-6 production

S Hess, A Rensing-Ehl, R Schwabe, P Bufler, and H Engelmann
J Immunol 1995 155: 4588-4595. [Abstract] [PDF]  

Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases

SA Johnson, CM Pleiman, L Pao, J Schneringer, K Hippen, and JC Cambier
J Immunol 1995 155: 4596-4603. [Abstract] [PDF]  

Prostaglandin E2 at priming of naive CD4+ T cells inhibits acquisition of ability to produce IFN-gamma and IL-2, but not IL-4 and IL-5

K Katamura, N Shintaku, Y Yamauchi, T Fukui, Y Ohshima, M Mayumi, and K Furusho
J Immunol 1995 155: 4604-4612. [Abstract] [PDF]  

Alterations in cytokine and antibody production following chemical sympathectomy in two strains of mice

B Kruszewska, SY Felten, and JA Moynihan
J Immunol 1995 155: 4613-4620. [Abstract] [PDF]  

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

M Marinaro, HF Staats, T Hiroi, RJ Jackson, M Coste, PN Boyaka, N Okahashi, M Yamamoto, H Kiyono, and H Bluethmann
J Immunol 1995 155: 4621-4629. [Abstract] [PDF]  

Expression of ecto-adenosine deaminase and CD26 in human T cells triggered by the TCR-CD3 complex. Possible role of adenosine deaminase as costimulatory molecule

M Martin, J Huguet, JJ Centelles, and R Franco
J Immunol 1995 155: 4630-4643. [Abstract] [PDF]  

Bcl-2 blocks glucocorticoid- but not Fas- or activation-induced apoptosis in a T cell hybridoma

SA Memon, MB Moreno, D Petrak, and CM Zacharchuk
J Immunol 1995 155: 4644-4652. [Abstract] [PDF]  

Stimulation of thymocytes before and after positive selection results in the induction of different NF-kappa B/Rel protein complexes

NC Moore, J Girdlestone, G Anderson, JJ Owen, and EJ Jenkinson
J Immunol 1995 155: 4653-4660. [Abstract] [PDF]  

IL-12 as mediator and adjuvant for the induction of contact sensitivity in vivo

G Muller, J Saloga, T Germann, G Schuler, J Knop, and AH Enk
J Immunol 1995 155: 4661-4668. [Abstract] [PDF]  

Induction of tolerance in freshly isolated alloreactive T cells by activated T cell stimulators is not due to the absence of CD28-B7 interaction

E Satyaraj, S Rath, and V Bal
J Immunol 1995 155: 4669-4675. [Abstract] [PDF]  

Processing of exogenous heat-aggregated (denatured) and particulate (native) hepatitis B surface antigen for class I-restricted epitope presentation

R Schirmbeck, W Bohm, K Melber, and J Reimann
J Immunol 1995 155: 4676-4684. [Abstract] [PDF]  

Regulation of IkB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways

NM Steffan, GD Bren, B Frantz, MJ Tocci, EA O'Neill, and CV Paya
J Immunol 1995 155: 4685-4691. [Abstract] [PDF]  

Early activation signal transduction pathways of Th1 and Th2 cell clones stimulated with anti-CD3. Roles of protein tyrosine kinases in the signal for IL-2 and IL-4 production

T Tamura, H Nakano, H Nagase, T Morokata, O Igarashi, Y Oshimi, S Miyazaki, and H Nariuchi
J Immunol 1995 155: 4692-4701. [Abstract] [PDF]  

CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase

KE Truitt, J Shi, S Gibson, LG Segal, GB Mills, and JB Imboden
J Immunol 1995 155: 4702-4710. [Abstract] [PDF]  

Differentiation to T helper cells in the thymus. Gradual acquisition of T helper cell function by CD3+CD4+ cells

D Vanhecke, B Verhasselt, V Debacker, G Leclercq, J Plum, and B Vandekerckhove
J Immunol 1995 155: 4711-4718. [Abstract] [PDF]  

Mapping of receptor binding sites on IL-1 beta by reconstruction of IL- 1ra-like domains

D Boraschi, P Bossu, P Ruggiero, A Tagliabue, R Bertini, G Macchia, C Gasbarro, L Pellegrini, G Melillo, and E Ulisse
J Immunol 1995 155: 4719-4725. [Abstract] [PDF]  

TAP associates with a unique class I conformation, whereas calnexin associates with multiple class I forms in mouse and man

BM Carreno, JC Solheim, M Harris, I Stroynowski, JM Connolly, and TH Hansen
J Immunol 1995 155: 4726-4733. [Abstract] [PDF]  

Non-sense and missense mutations in the structural genes of complement component C1q A and C chains are linked with two different types of complete selective C1q deficiencies

F Petry, DT Le, M Kirschfink, and M Loos
J Immunol 1995 155: 4734-4738. [Abstract] [PDF]  

Identification of a mouse protein homologous to the human CD6 T cell surface protein and sequence of the corresponding cDNA

WH Robinson, SS Prohaska, JC Santoro, HL Robinson, and JR Parnes
J Immunol 1995 155: 4739-4748. [Abstract] [PDF]  

Differences in MHC class I self peptide repertoires among HLA-A2 subtypes

T Sudo, N Kamikawaji, A Kimura, Y Date, CJ Savoie, H Nakashima, E Furuichi, S Kuhara, and T Sasazuki
J Immunol 1995 155: 4749-4756. [Abstract] [PDF]  

Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR

AB Vogt, LJ Stern, C Amshoff, B Dobberstein, GJ Hammerling, and H Kropshofer
J Immunol 1995 155: 4757-4765. [Abstract] [PDF]  

Identification of an HLA-A11-restricted epitope from the tandem repeat domain of the epithelial tumor antigen mucin

N Domenech, RA Henderson, and OJ Finn
J Immunol 1995 155: 4766-4774. [Abstract] [PDF]  

Induction of cell-mediated immune responses to human immunodeficiency virus type 1 Gag protein by using Listeria monocytogenes as a live vaccine vector

FR Frankel, S Hegde, J Lieberman, and Y Paterson
J Immunol 1995 155: 4775-4782. [Abstract] [PDF]  

Expression of activated H-rasval12 in nontumorigenic and non-cross- reactive syngeneic cells induces tumor antigens cross-reactive with rat mammary adenocarcinoma 13762

AB Frey and S Cestari
J Immunol 1995 155: 4783-4789. [Abstract] [PDF]  

The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection

GB Huffnagle, RM Strieter, TJ Standiford, RA McDonald, MD Burdick, SL Kunkel, and GB Toews
J Immunol 1995 155: 4790-4797. [Abstract] [PDF]  

IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii

LH Kasper, T Matsuura, and IA Khan
J Immunol 1995 155: 4798-4804. [Abstract] [PDF]  

Constitutive production of IL-2 by human carcinoma cells, expression of IL-2 receptor, and tumor cell growth

WC Lin, S Yasumura, Y Suminami, MW Sung, S Nagashima, J Stanson, and TL Whiteside
J Immunol 1995 155: 4805-4816. [Abstract] [PDF]  

Nonviable bacterial antigens administered with IL-12 generate antigen- specific T cell responses and protective immunity against Listeria monocytogenes

MA Miller, MJ Skeen, and HK Ziegler
J Immunol 1995 155: 4817-4828. [Abstract] [PDF]  

Increased susceptibility of fas mutant MRL-lpr/lpr mice to staphylococcal enterotoxin B-induced septic shock

JD Mountz, TJ Baker, DR Borcherding, H Bluethmann, T Zhou, and CK Edwards, 3rd
J Immunol 1995 155: 4829-4837. [Abstract] [PDF]  

High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens

BJ Rutledge, H Rayburn, R Rosenberg, RJ North, RP Gladue, CL Corless, and BJ Rollins
J Immunol 1995 155: 4838-4843. [Abstract] [PDF]  

Early IL-4 production by non-CD4+ cells at the site of antigen deposition predicts the development of a T helper 2 cell response to Schistosoma mansoni eggs

EA Sabin and EJ Pearce
J Immunol 1995 155: 4844-4853. [Abstract] [PDF]  

Parasite strain specificity of bovine cytotoxic T cell responses to Theileria parva is determined primarily by immunodominance

EL Taracha, BM Goddeeris, AJ Teale, SJ Kemp, and WI Morrison
J Immunol 1995 155: 4854-4860. [Abstract] [PDF]  

Triggering of complement receptors CR1 (CD35) and CR3 (CD11b/CD18) induces nuclear translocation of NF-kappa B (p50/p65) in human monocytes and enhances viral replication in HIV-infected monocytic cells

N Thieblemont, N Haeffner-Cavaillon, A Haeffner, B Cholley, L Weiss, and MD Kazatchkine
J Immunol 1995 155: 4861-4867. [Abstract] [PDF]  

Soluble CD23 directly activates monocytes to contribute to the antigen- independent stimulation of resting T cells

M Armant, M Rubio, G Delespesse, and M Sarfati
J Immunol 1995 155: 4868-4875. [Abstract] [PDF]  

Neutrophil inhibitory factor prevents neutrophil-dependent lung injury

JW Barnard, MG Biro, SK Lo, S Ohno, MA Carozza, M Moyle, HR Soule, and AB Malik
J Immunol 1995 155: 4876-4881. [Abstract] [PDF]  

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes

P Gasque, P Chan, M Fontaine, A Ischenko, M Lamacz, O Gotze, and BP Morgan
J Immunol 1995 155: 4882-4889. [Abstract] [PDF]  

A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis

DA Geller, ME de Vera, DA Russell, RA Shapiro, AK Nussler, RL Simmons, and TR Billiar
J Immunol 1995 155: 4890-4898. [Abstract] [PDF]  

Lipopolysaccharide-induced change of phosphorylation of two cytosolic proteins in human monocytes is prevented by inhibitors of ADP- ribosylation

H Heine, AJ Ulmer, HD Flad, and S Hauschildt
J Immunol 1995 155: 4899-4908. [Abstract] [PDF]  

Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-alpha and IL-6 release by endotoxin-stimulated macrophages

T Kambayashi, CO Jacob, D Zhou, N Mazurek, M Fong, and G Strassmann
J Immunol 1995 155: 4909-4916. [Abstract] [PDF]  

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes

PA Kiener, P Moran-Davis, BM Rankin, AF Wahl, A Aruffo, and D Hollenbaugh
J Immunol 1995 155: 4917-4925. [Abstract] [PDF]  

TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor-bearing mice

H Maeda, H Kuwahara, Y Ichimura, M Ohtsuki, S Kurakata, and A Shiraishi
J Immunol 1995 155: 4926-4932. [Abstract] [PDF]  

Differential utilization of IFN-gamma-responsive elements in two maturationally distinct macrophage cell lines

MA McDowell, DM Lucas, CM Nicolet, and DM Paulnock
J Immunol 1995 155: 4933-4938. [Abstract] [PDF]  

Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product

R Moqbel, S Ying, J Barkans, TM Newman, P Kimmitt, M Wakelin, L Taborda-Barata, Q Meng, CJ Corrigan, and SR Durham
J Immunol 1995 155: 4939-4947. [Abstract] [PDF]  

Differential effects of granulocyte-macrophage colony-stimulating factor on eosinophil and neutrophil superoxide anion generation

M Nagata, JB Sedgwick, and WW Busse
J Immunol 1995 155: 4948-4954. [Abstract] [PDF]  

Classical complement pathway activation on nucleated cells. Role of factor H in the control of deposited C3b

MW Ollert, K David, R Bredehorst, and CW Vogel
J Immunol 1995 155: 4955-4962. [Abstract] [PDF]  

p21ras links Fc epsilon RI to NF-AT family member in mast cells. The AP3-like factor in this cell type is an NF-AT family member

EE Prieschl, GG Pendl, NE Harrer, and T Baumruker
J Immunol 1995 155: 4963-4970. [Abstract] [PDF]  

Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis

W Schwaeble, MK Schafer, F Petry, T Fink, D Knebel, E Weihe, and M Loos
J Immunol 1995 155: 4971-4978. [Abstract] [PDF]  

Regulation of polymorphonuclear neutrophil CD16 and CD11b/CD18 expression by matrix proteins during hypoxia is VLA-5, VLA-6 dependent

H Simms and R D'Amico
J Immunol 1995 155: 4979-4990. [Abstract] [PDF]  

Whither clinical immunology?

RR Rich
J Immunol 1995 155: 4992-4995. [PDF]  

Construction and characterization of a humanized anti-gamma-Ig receptor type I (Fc gamma RI) monoclonal antibody

RF Graziano, PR Tempest, P White, T Keler, Y Deo, H Ghebremariam, K Coleman, LC Pfefferkorn, MW Fanger, and PM Guyre
J Immunol 1995 155: 4996-5002. [Abstract] [PDF]  

An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis

WJ Karpus, NW Lukacs, BL McRae, RM Strieter, SL Kunkel, and SD Miller
J Immunol 1995 155: 5003-5010. [Abstract] [PDF]  

Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells

A Khoruts, SD Miller, and MK Jenkins
J Immunol 1995 155: 5011-5017. [Abstract] [PDF]  

Evidence for superantigen involvement in cardiovascular injury due to Kawasaki syndrome

DY Leung, RC Giorno, LV Kazemi, PA Flynn, and JB Busse
J Immunol 1995 155: 5018-5021. [Abstract] [PDF]  

Delineation of additional genetic bases for C8 beta deficiency. Prevalence of null alleles and predominance of C-->T transition in their genesis

L Saucedo, L Ackermann, AE Platonov, A Gewurz, RM Rakita, and P Densen
J Immunol 1995 155: 5022-5028. [Abstract] [PDF]  

Elevated Th1- or Th0-like cytokine mRNA in peripheral circulation of patients with rheumatoid arthritis. Modulation by treatment with anti- ICAM-1 correlates with clinical benefit

H Schulze-Koops, PE Lipsky, AF Kavanaugh, and LS Davis
J Immunol 1995 155: 5029-5037. [Abstract] [PDF]  

Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration

AF Suffredini, D Reda, SM Banks, M Tropea, JM Agosti, and R Miller
J Immunol 1995 155: 5038-5045. [Abstract] [PDF]  

CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus

EC Wang, PA Moss, P Frodsham, PJ Lehner, JI Bell, and LK Borysiewicz
J Immunol 1995 155: 5046-5056. [Abstract] [PDF]  

Localization of an Fc-binding reactivity to the constant region of human IgG4. Implications for the pathogenesis of rheumatoid arthritis

DJ Zack, M Stempniak, AL Wong, and RH Weisbart
J Immunol 1995 155: 5057-5063. [Abstract] [PDF]  

T cell epitope mapping of ragweed pollen allergen Ambrosia artemisiifolia (Amb a 5) and Ambrosia trifida (Amb t 5) and the role of free sulfhydryl groups in T cell recognition

X Zhu, JL Greenstein, BL Rogers, and MC Kuo
J Immunol 1995 155: 5064-5073. [Abstract] [PDF]  

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